PLOS Global Public Health,
Journal Year:
2024,
Volume and Issue:
4(3), P. e0002046 - e0002046
Published: March 6, 2024
Regular
booster
vaccination
programmes
help
protect
the
most
vulnerable
from
COVID-19
and
limit
pressure
on
health
systems.
Existing
studies
find
doses
to
be
effective
in
preventing
hospital
admissions
deaths
but
focus
individual
effects,
failing
consider
population
impact
of
incomplete
coverage
seasonal
patterns
disease
transmission.
We
estimated
effectiveness
2022
spring
programme,
available
for
those
aged
75
years
older,
residents
care
homes,
adults
with
weakened
immune
systems,
bed
occupancy
England.
Booster
vaccine
eligible
increased
rapidly
months
after
rollout
(from
21
st
March
2022),
flattening
out
just
below
80%
by
July
2022.
used
interrupted
time
series
analysis
estimate
a
23.7%
overall
reduction
rate
following
statistically
significant
benefit
6–12
weeks
rollout.
In
absence
we
calculate
that
total
380,104
additional
bed-days
would
have
been
occupied
patients
4
th
April
31
August
(95%
CI:
–122,842
1,034,590).
The
programme
delayed
shortened
duration
peak
while
not
reducing
its
magnitude.
sensitivity
analyses
adjusting
start
post-intervention
period
or
removing
infection
over
60s
model,
effect
remained
similar.
Our
findings
suggest
timing
is
critical
consideration
implementation
policymakers
cannot
rely
intermittent
high-risk
groups
alone
mitigate
anticipated
peaks
due
epidemics.
Human Vaccines & Immunotherapeutics,
Journal Year:
2024,
Volume and Issue:
20(1)
Published: Feb. 18, 2024
Our
study
aims
to
assess
the
public's
perceptions
of
respiratory
syncytial
virus
(RSV)
and
attitudes
toward
RSV
vaccine
identify
associated
factors
in
China.
A
nationwide
cross-sectional
survey
conducted
using
an
online
platform
between
August
16
September
14,
2023.
Questions
related
socio-demographics,
awareness,
knowledge,
susceptibility
severity
RSV,
were
included
questionnaire.
We
used
chi-square
test
logistic
regression
model
explore
factors.
Overall,
2133
individuals
this
study.
Nearly
a
quarter
participants
(24.3%)
indicated
that
they
had
never
heard
RSV.
The
proportion
aged
over
50
years
reporting
having
(36.5%)
low
knowledge
level
(55.3%)
was
significantly
higher
other
younger
age
groups.
More
than
half
(55.7%)
exhibited
concerning
infection.
total
68.4%
expressed
willingness
receive
vaccine.
Younger
positively
with
be
vaccinated.
most
frequent
reason
for
declining
"Concern
about
vaccine's
safety
or
side
effects."
About
60%
considered
price
below
200
CNY
(28
USD)
as
acceptable.
awareness
perceived
infection
limited
Chinese
public.
It
is
necessary
take
measures
address
acceptability
among
older
adults.
Open Journal of Epidemiology,
Journal Year:
2025,
Volume and Issue:
15(01), P. 1 - 18
Published: Jan. 1, 2025
The
emergence
of
the
SARS-CoV-2
virus
resulted
in
a
health
and
economic
crisis
worldwide.
Although
everyone
is
susceptible
to
COVID-19,
elderly
have
compromised
immune
systems
often
suffer
from
chronic
underlying
diseases,
which
makes
them
more
vulnerable.
This
study
aims
assess
variation
COVID-19
vaccine
distribution
patterns
across
different
age
groups
European
countries
understand
extent
prioritized
vulnerable
(age
>
70)
their
vaccination
programs.
utilized
open
data
Center
for
Disease
Prevention
Control
(ECDC)
employed
an
observational,
retrospective
design
examine
among
various
several
September
2021
2023.
Results
reveal
that
rates
increase
with
age,
peaking
at
25
-
49
group
(1.34
×
10−4),
after
there
was
decline
rate.
Analysis
variance
(ANOVA)
used
investigate
equality
29
Europe,
p-value
during
period
as
no
country
achieved
70%
coverage
aimed
by
WHO.
Continuous
efforts
must
be
made
ensure
larger
this
population
order
protect
severe
outcomes
region.
BMC Geriatrics,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Jan. 12, 2024
Abstract
Background
The
suboptimal
uptake
of
COVID-19
and
influenza
vaccines
among
those
with
non-communicable
chronic
diseases
is
a
public
health
concern,
because
it
poses
higher
risk
severe
illness
for
individuals
underlying
conditions,
emphasizing
the
need
to
address
barriers
vaccination
ensure
adequate
protection
this
vulnerable
population.
In
present
study,
we
aimed
identify
whether
people
illnesses
are
more
likely
get
vaccinated
against
in
European
Union.
Methods
Cross-sectional
data
on
49,253
men
(n
=
20,569)
women
28,684)
were
obtained
from
ninth
round
Survey
Health,
Ageing
Retirement
Europe
(June
–
August,
2021).
outcome
variables
self-reported
vaccine
status.
association
between
six
preexisting
conditions
including
high
blood
pressure,
cholesterol,
lung
disease,
diabetes,
bronchitis,
asthma
was
estimated
using
binary
logistic
regression
methods.
Results
coverage
ranged
close
100%
Denmark
(98.2%)
Malta
less
than
50%
Bulgaria
(19.1%)
Romania
(32.7%).
countries
highest
percentage
participants
included
(66.7%),
Spain
(63.7%)
Netherlands
(62.5%),
lowest
(3.7%),
Slovakia
(5.8%)
Poland
(9.2%).
Participants
pressure
3%
[Risk
difference
(RD)
-0.03,
95%
CI
-0.04,
-0.03]
report
taking
[RD
CI=
-0.01]
vaccine.
Those
disease
4%
-0.06,
2%
[RD=
-0.02,
Men
have
reported
both
vaccines.
Conclusions
Current
findings
indicate
adult
EU
countries.
take
Vaccine,
Journal Year:
2025,
Volume and Issue:
55, P. 127042 - 127042
Published: March 29, 2025
Vaccine
hesitancy
remains
a
critical
public
health
challenge,
influenced
by
demographic
and
cultural
factors.
In
Greece,
age
gender
are
significant
determinants.
This
study
aimed
to
develop
validate
culturally
adapted
survey
instrument,
the
Hellenic
Attitudes
towards
Vaccination
Index
(HAVI),
assess
beliefs
attitudes
vaccination
among
Greek
adults.
Additionally,
sought
investigate
impact
of
on
vaccine
hesitancy.
By
adapting
an
existing
questionnaire,
we
ensured
linguistic
relevance
context.
novel
employed
cross-sectional
design,
recruiting
184
adults
(92
males,
mean
=
40.2
years;
92
females,
38.8
years).
Participants
completed
22-item
HAVI
questionnaire.
Data
analysis
included
Exploratory
Factor
Analysis
(EFA),
correlation
analysis,
internal
consistency
assessment,
regression
analysis.
EFA
revealed
four-factor
structure:
(1)
Perceived
Safety,
(2)
Effects,
(3)
Towards
Health
Authorities,
(4)
Benefit
Mandatory
Vaccines.
A
heatmap
provided
intuitive
visualization
item-factor
relationships.
The
instrument
demonstrated
excellent
reliability
(Cronbach's
α
0.92).
Although
explaining
small
moderate
amount
variance,
there
were
key
findings
identified
differences,
with
females
showing
higher
hesitancy,
inverse
between
positive
attitudes.
represents
reliable
practical
tool
for
assessing
in
adults,
offering
valuable
insights
guide
targeted
strategies.
npj Digital Medicine,
Journal Year:
2023,
Volume and Issue:
6(1)
Published: May 25, 2023
Chatbots
have
become
an
increasingly
popular
tool
in
the
field
of
health
services
and
communications.
Despite
chatbots'
significance
amid
COVID-19
pandemic,
few
studies
performed
a
rigorous
evaluation
effectiveness
chatbots
improving
vaccine
confidence
acceptance.
In
Thailand,
Hong
Kong,
Singapore,
from
February
11th
to
June
30th,
2022,
we
conducted
multisite
randomised
controlled
trials
(RCT)
on
2,045
adult
guardians
children
seniors
who
were
unvaccinated
or
had
delayed
vaccinations.
After
week
using
chatbots,
differences
acceptance
compared
between
intervention
control
groups.
Compared
non-users,
fewer
chatbot
users
reported
decreased
Thailand
child
group
[Intervention:
4.3
%
vs.
Control:
17%,
P
=
0.023].
However,
more
[26%
12%,
0.028]
Kong
safety
[29%
10%,
0.041]
Singapore
group.
There
was
no
statistically
significant
change
senior
Employing
RE-AIM
framework,
process
indicated
strong
implementation
support
for
stakeholders,
with
high
levels
sustainability
scalability.
This
multisite,
parallel
RCT
study
found
mixed
success
among
Asian
subpopulations.
Further
that
link
usage
real-world
uptake
are
needed
augment
evidence
employing
advance
Therapeutic Advances in Vaccines and Immunotherapy,
Journal Year:
2025,
Volume and Issue:
13
Published: Jan. 1, 2025
Background:
Respiratory
syncytial
virus
(RSV)
poses
a
significant
respiratory
health
risk
to
senior
citizens,
contributing
substantially
hospitalizations
and
mortality.
With
the
recent
approval
of
three
RSV
vaccines
for
elderly,
it
is
critical
understand
factors
that
can
shape
vaccination
attitudes
inform
public
strategies
enhance
uptake
among
this
vulnerable
population.
Objectives:
This
study
aimed
investigate
potential
could
influence
toward
citizens
in
Arab
countries.
Design:
A
multinational
cross-sectional
study,
adhering
STROBE
guidelines,
was
conducted
using
survey
instrument
previously
validated
through
exploratory
factor
analysis
assess
newly
approved
vaccine.
Methods:
self-administered
online
distributed
conveniently
mainly
across
five
The
collected
data
on
demographics,
history,
key
constructs
related
vaccine
attitude,
including
“Fear,”
“Information,”
“Accessibility,”
“Benefits,”
“Conspiracy.”
Results:
total
483
participants
were
included
with
majority
from
countries:
Jordan
(
n
=
239,
49.5%),
Kuwait
74,
15.3%),
Egypt
68,
14.1%),
Saudi
Arabia
51,
10.6%),
UAE
23,
4.8%),
alongside
other
nations
28,
5.8%).
Among
respondents,
51.1%
247)
expressed
acceptance
vaccine,
22.4%
108)
hesitant,
26.5%
128)
exhibited
refusal.
Multivariate
identified
perceived
benefits
(β
0.484,
p
<
0.001),
information
needs
0.229,
previous
history
0.087,
0.016)
as
positive
predictors
acceptance.
Conversely,
stronger
conspiracy
beliefs
−0.083,
0.035)
associated
resistance.
Fear
accessibility
not
attitudes.
Conclusion:
findings
showed
benefits,
access
reliable
information,
are
essential
promote
seniors.
These
recommended
improve
BMC Geriatrics,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: March 24, 2025
Abstract
Background
Depression,
anxiety
and
loneliness
are
common
among
older
patients.
As
a
potential
psychological
buffer
against
these
challenges,
meaning
in
life
(MIL)
remains
underexplored
longitudinal
studies
within
this
population.
This
study
aims
to
examine
the
relationship
of
MIL
with
depression,
anxiety,
adults
multimorbidity
Hong
Kong.
Methods
In
prospective
cohort
1077
primary
care
patients
aged
60
or
above
Kong,
was
assessed
using
an
item
from
Chinese
Purpose
Life
test
at
baseline,
1st
follow-up
(median:
1.3
years),
2nd
3.1
years).
were
Patient
Health
Questionnaire,
Generalized
Anxiety
Disorder,
De
Jong
Gierveld
Loneliness
scales,
respectively,
each
time
point.
Cross-lagged
relationships
between
measures
examined
cross-lagged
panel
models.
Results
Participants
had
average
age
70.0
years,
70.1%
being
female.
Higher
predicted
lower
depression
(β
=
-0.15),
-0.13),
overall
-0.18),
emotional
social
-0.16)
follow-up.
Additionally,
higher
-0.12),
-0.11),
-0.10)
At
-0.21),
but
not
follow-up,
-0.23),
-0.16),
-0.10),
loneliness,
Conclusions
The
findings
suggest
bidirectional
mental
health
outcomes
Emotional
demonstrated
more
consistent
association
than
loneliness.
Further
research
is
needed
understand
underlying
mechanisms
develop
targeted
interventions
addressing
both
problems.
BMC Geriatrics,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: March 31, 2024
Abstract
Background
Vaccination
is
important
to
reduce
disease-associated
morbidity
and
mortality
in
an
ageing
global
population.
While
older
adults
are
more
likely
than
younger
accept
vaccines,
some
remain
hesitant.
We
sought
understand
how
traumatic
events,
psychological
distress
social
support
contribute
adults’
intention
receive
a
COVID-19
vaccine
whether
these
experiences
change
with
age.
Methods
analysed
survey
data
collected
as
part
of
the
Sax
Institute’s
45
Up
Study
population
Australian
aged
60
years
over.
Data
were
derived
from
COVID
Insights
study;
series
supplementary
surveys
about
participants
experienced
pandemic.
Results
Higher
was
associated
greater
(adjusted
odds
ratio
(aOR):1.08;
95%CI:1.06–1.11;
p
<.001)
while
lower
personally
experiencing
serious
illness,
injury
or
assault
last
12
months
(aOR:0.79;
95%
CI:0.64–0.98;
=.03).
Social
experience
events
increased
significantly
age,
decreased.
Conclusions
There
may
be
factors
beyond
risks
that
play
role
acceptance
Older
Australians
on
end
age
spectrum
have
specific
needs
address
their
hesitancy
overlooked.