The impact of the 2022 spring COVID-19 booster vaccination programme on hospital occupancy in England: An interrupted time series analysis DOI Creative Commons
Vageesh Jain, Gabriele Kerr, Thomas Beaney

et al.

PLOS Global Public Health, Journal Year: 2024, Volume and Issue: 4(3), P. e0002046 - e0002046

Published: March 6, 2024

Regular booster vaccination programmes help protect the most vulnerable from COVID-19 and limit pressure on health systems. Existing studies find doses to be effective in preventing hospital admissions deaths but focus individual effects, failing consider population impact of incomplete coverage seasonal patterns disease transmission. We estimated effectiveness 2022 spring programme, available for those aged 75 years older, residents care homes, adults with weakened immune systems, bed occupancy England. Booster vaccine eligible increased rapidly months after rollout (from 21 st March 2022), flattening out just below 80% by July 2022. used interrupted time series analysis estimate a 23.7% overall reduction rate following statistically significant benefit 6–12 weeks rollout. In absence we calculate that total 380,104 additional bed-days would have been occupied patients 4 th April 31 August (95% CI: –122,842 1,034,590). The programme delayed shortened duration peak while not reducing its magnitude. sensitivity analyses adjusting start post-intervention period or removing infection over 60s model, effect remained similar. Our findings suggest timing is critical consideration implementation policymakers cannot rely intermittent high-risk groups alone mitigate anticipated peaks due epidemics.

Language: Английский

Determinants of COVID-19 vaccination status and hesitancy among older adults in China DOI Open Access

Gewei Wang,

Yao Yao, Yafeng Wang

et al.

Nature Medicine, Journal Year: 2023, Volume and Issue: 29(3), P. 623 - 631

Published: Jan. 31, 2023

Language: Английский

Citations

85

Perceptions about respiratory syncytial virus (RSV) and attitudes toward the RSV vaccine among the general public in China: A cross-sectional survey DOI Creative Commons
Qiang Wang, Shixin Xiu, Liuqing Yang

et al.

Human Vaccines & Immunotherapeutics, Journal Year: 2024, Volume and Issue: 20(1)

Published: Feb. 18, 2024

Our study aims to assess the public's perceptions of respiratory syncytial virus (RSV) and attitudes toward RSV vaccine identify associated factors in China. A nationwide cross-sectional survey conducted using an online platform between August 16 September 14, 2023. Questions related socio-demographics, awareness, knowledge, susceptibility severity RSV, were included questionnaire. We used chi-square test logistic regression model explore factors. Overall, 2133 individuals this study. Nearly a quarter participants (24.3%) indicated that they had never heard RSV. The proportion aged over 50 years reporting having (36.5%) low knowledge level (55.3%) was significantly higher other younger age groups. More than half (55.7%) exhibited concerning infection. total 68.4% expressed willingness receive vaccine. Younger positively with be vaccinated. most frequent reason for declining "Concern about vaccine's safety or side effects." About 60% considered price below 200 CNY (28 USD) as acceptable. awareness perceived infection limited Chinese public. It is necessary take measures address acceptability among older adults.

Language: Английский

Citations

10

COVID-19 Vaccine Distribution Patterns for Prioritized Age Group: Analysis of European Nations DOI Open Access

Ogbonnaya Ezichi,

Victor Okpanachi,

Joy Jibunoh

et al.

Open Journal of Epidemiology, Journal Year: 2025, Volume and Issue: 15(01), P. 1 - 18

Published: Jan. 1, 2025

The emergence of the SARS-CoV-2 virus resulted in a health and economic crisis worldwide. Although everyone is susceptible to COVID-19, elderly have compromised immune systems often suffer from chronic underlying diseases, which makes them more vulnerable. This study aims assess variation COVID-19 vaccine distribution patterns across different age groups European countries understand extent prioritized vulnerable (age > 70) their vaccination programs. utilized open data Center for Disease Prevention Control (ECDC) employed an observational, retrospective design examine among various several September 2021 2023. Results reveal that rates increase with age, peaking at 25 - 49 group (1.34 × 10−4), after there was decline rate. Analysis variance (ANOVA) used investigate equality 29 Europe, p-value during period as no country achieved 70% coverage aimed by WHO. Continuous efforts must be made ensure larger this population order protect severe outcomes region.

Language: Английский

Citations

1

Uptake of COVID-19 and influenza vaccines in relation to preexisting chronic conditions in the European countries DOI Creative Commons
Shangfeng Tang,

Lü Ji,

Ghose Bishwajit

et al.

BMC Geriatrics, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 12, 2024

Abstract Background The suboptimal uptake of COVID-19 and influenza vaccines among those with non-communicable chronic diseases is a public health concern, because it poses higher risk severe illness for individuals underlying conditions, emphasizing the need to address barriers vaccination ensure adequate protection this vulnerable population. In present study, we aimed identify whether people illnesses are more likely get vaccinated against in European Union. Methods Cross-sectional data on 49,253 men (n = 20,569) women 28,684) were obtained from ninth round Survey Health, Ageing Retirement Europe (June – August, 2021). outcome variables self-reported vaccine status. association between six preexisting conditions including high blood pressure, cholesterol, lung disease, diabetes, bronchitis, asthma was estimated using binary logistic regression methods. Results coverage ranged close 100% Denmark (98.2%) Malta less than 50% Bulgaria (19.1%) Romania (32.7%). countries highest percentage participants included (66.7%), Spain (63.7%) Netherlands (62.5%), lowest (3.7%), Slovakia (5.8%) Poland (9.2%). Participants pressure 3% [Risk difference (RD) -0.03, 95% CI -0.04, -0.03] report taking [RD CI= -0.01] vaccine. Those disease 4% -0.06, 2% [RD= -0.02, Men have reported both vaccines. Conclusions Current findings indicate adult EU countries. take

Language: Английский

Citations

5

HAVI: A novel tool to explore vaccine hesitancy among adults in Greece DOI Creative Commons

Aikaterini S. Stravoravdi,

Aristea I. Ladas, Christos A. Frantzidιs

et al.

Vaccine, Journal Year: 2025, Volume and Issue: 55, P. 127042 - 127042

Published: March 29, 2025

Vaccine hesitancy remains a critical public health challenge, influenced by demographic and cultural factors. In Greece, age gender are significant determinants. This study aimed to develop validate culturally adapted survey instrument, the Hellenic Attitudes towards Vaccination Index (HAVI), assess beliefs attitudes vaccination among Greek adults. Additionally, sought investigate impact of on vaccine hesitancy. By adapting an existing questionnaire, we ensured linguistic relevance context. novel employed cross-sectional design, recruiting 184 adults (92 males, mean = 40.2 years; 92 females, 38.8 years). Participants completed 22-item HAVI questionnaire. Data analysis included Exploratory Factor Analysis (EFA), correlation analysis, internal consistency assessment, regression analysis. EFA revealed four-factor structure: (1) Perceived Safety, (2) Effects, (3) Towards Health Authorities, (4) Benefit Mandatory Vaccines. A heatmap provided intuitive visualization item-factor relationships. The instrument demonstrated excellent reliability (Cronbach's α 0.92). Although explaining small moderate amount variance, there were key findings identified differences, with females showing higher hesitancy, inverse between positive attitudes. represents reliable practical tool for assessing in adults, offering valuable insights guide targeted strategies.

Language: Английский

Citations

0

Effectiveness of chatbots on COVID vaccine confidence and acceptance in Thailand, Hong Kong, and Singapore DOI Creative Commons
Kristi Yoonsup Lee, Saudamini Vishwanath Dabak,

Vivian Hanxiao Kong

et al.

npj Digital Medicine, Journal Year: 2023, Volume and Issue: 6(1)

Published: May 25, 2023

Chatbots have become an increasingly popular tool in the field of health services and communications. Despite chatbots' significance amid COVID-19 pandemic, few studies performed a rigorous evaluation effectiveness chatbots improving vaccine confidence acceptance. In Thailand, Hong Kong, Singapore, from February 11th to June 30th, 2022, we conducted multisite randomised controlled trials (RCT) on 2,045 adult guardians children seniors who were unvaccinated or had delayed vaccinations. After week using chatbots, differences acceptance compared between intervention control groups. Compared non-users, fewer chatbot users reported decreased Thailand child group [Intervention: 4.3 % vs. Control: 17%, P = 0.023]. However, more [26% 12%, 0.028] Kong safety [29% 10%, 0.041] Singapore group. There was no statistically significant change senior Employing RE-AIM framework, process indicated strong implementation support for stakeholders, with high levels sustainability scalability. This multisite, parallel RCT study found mixed success among Asian subpopulations. Further that link usage real-world uptake are needed augment evidence employing advance

Language: Английский

Citations

12

Perceived benefits, information, vaccination history, and conspiracy beliefs as significant determinants of RSV vaccine acceptance among Arab seniors DOI Creative Commons
Malik Sallam,

Kholoud Al-Mahzoum,

Zainab Mansour Yousef

et al.

Therapeutic Advances in Vaccines and Immunotherapy, Journal Year: 2025, Volume and Issue: 13

Published: Jan. 1, 2025

Background: Respiratory syncytial virus (RSV) poses a significant respiratory health risk to senior citizens, contributing substantially hospitalizations and mortality. With the recent approval of three RSV vaccines for elderly, it is critical understand factors that can shape vaccination attitudes inform public strategies enhance uptake among this vulnerable population. Objectives: This study aimed investigate potential could influence toward citizens in Arab countries. Design: A multinational cross-sectional study, adhering STROBE guidelines, was conducted using survey instrument previously validated through exploratory factor analysis assess newly approved vaccine. Methods: self-administered online distributed conveniently mainly across five The collected data on demographics, history, key constructs related vaccine attitude, including “Fear,” “Information,” “Accessibility,” “Benefits,” “Conspiracy.” Results: total 483 participants were included with majority from countries: Jordan ( n = 239, 49.5%), Kuwait 74, 15.3%), Egypt 68, 14.1%), Saudi Arabia 51, 10.6%), UAE 23, 4.8%), alongside other nations 28, 5.8%). Among respondents, 51.1% 247) expressed acceptance vaccine, 22.4% 108) hesitant, 26.5% 128) exhibited refusal. Multivariate identified perceived benefits (β 0.484, p < 0.001), information needs 0.229, previous history 0.087, 0.016) as positive predictors acceptance. Conversely, stronger conspiracy beliefs −0.083, 0.035) associated resistance. Fear accessibility not attitudes. Conclusion: findings showed benefits, access reliable information, are essential promote seniors. These recommended improve

Language: Английский

Citations

0

Meaning in life: bidirectional relationship with depression, anxiety, and loneliness in a longitudinal cohort of older primary care patients with multimorbidity DOI Creative Commons
King Wa Tam, De‐Xing Zhang,

Yiqi Li

et al.

BMC Geriatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 24, 2025

Abstract Background Depression, anxiety and loneliness are common among older patients. As a potential psychological buffer against these challenges, meaning in life (MIL) remains underexplored longitudinal studies within this population. This study aims to examine the relationship of MIL with depression, anxiety, adults multimorbidity Hong Kong. Methods In prospective cohort 1077 primary care patients aged 60 or above Kong, was assessed using an item from Chinese Purpose Life test at baseline, 1st follow-up (median: 1.3 years), 2nd 3.1 years). were Patient Health Questionnaire, Generalized Anxiety Disorder, De Jong Gierveld Loneliness scales, respectively, each time point. Cross-lagged relationships between measures examined cross-lagged panel models. Results Participants had average age 70.0 years, 70.1% being female. Higher predicted lower depression (β = -0.15), -0.13), overall -0.18), emotional social -0.16) follow-up. Additionally, higher -0.12), -0.11), -0.10) At -0.21), but not follow-up, -0.23), -0.16), -0.10), loneliness, Conclusions The findings suggest bidirectional mental health outcomes Emotional demonstrated more consistent association than loneliness. Further research is needed understand underlying mechanisms develop targeted interventions addressing both problems.

Language: Английский

Citations

0

Relationship between vaccine hesitancy and vaccination behaviors: Systematic review and meta-analysis of observational studies DOI

Xuying Yang,

Naiyang Shi, Chang Liu

et al.

Vaccine, Journal Year: 2023, Volume and Issue: 42(2), P. 99 - 110

Published: Dec. 11, 2023

Language: Английский

Citations

9

The experience of traumatic events, psychological distress, and social support: links to COVID-19 vaccine hesitancy and trends with age in a group of older Australians DOI Creative Commons

Maria Christou-Ergos,

Kerrie Wiley, Julie Leask

et al.

BMC Geriatrics, Journal Year: 2024, Volume and Issue: 24(1)

Published: March 31, 2024

Abstract Background Vaccination is important to reduce disease-associated morbidity and mortality in an ageing global population. While older adults are more likely than younger accept vaccines, some remain hesitant. We sought understand how traumatic events, psychological distress social support contribute adults’ intention receive a COVID-19 vaccine whether these experiences change with age. Methods analysed survey data collected as part of the Sax Institute’s 45 Up Study population Australian aged 60 years over. Data were derived from COVID Insights study; series supplementary surveys about participants experienced pandemic. Results Higher was associated greater (adjusted odds ratio (aOR):1.08; 95%CI:1.06–1.11; p <.001) while lower personally experiencing serious illness, injury or assault last 12 months (aOR:0.79; 95% CI:0.64–0.98; =.03). Social experience events increased significantly age, decreased. Conclusions There may be factors beyond risks that play role acceptance Older Australians on end age spectrum have specific needs address their hesitancy overlooked.

Language: Английский

Citations

2