Dimming the corona: studying SARS-coronavirus-2 at reduced biocontainment level using replicons and virus-like particles DOI Creative Commons
Grace Neilsen,

Asha Maria Mathew,

J.M. Castro

et al.

mBio, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

The coronavirus-induced disease 19 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections, has had a devastating impact on millions of lives globally, with mortality rates and catastrophic social implications. Developing tools for effective vaccine strategies platforms is essential controlling preventing the recurrence such pandemics. Moreover, molecular virology that facilitate study viral pathogens, mutations, interactions various host proteins are essential. Viral replicon- virus-like particle (VLP)-based systems excellent examples tools. This review outlines importance, advantages, disadvantages both VLP-based have been developed SARS-CoV-2 helped scientific community in dimming intensity COVID-19 pandemic.

Language: Английский

Dimming the corona: studying SARS-coronavirus-2 at reduced biocontainment level using replicons and virus-like particles DOI Creative Commons
Grace Neilsen,

Asha Maria Mathew,

J.M. Castro

et al.

mBio, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

The coronavirus-induced disease 19 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections, has had a devastating impact on millions of lives globally, with mortality rates and catastrophic social implications. Developing tools for effective vaccine strategies platforms is essential controlling preventing the recurrence such pandemics. Moreover, molecular virology that facilitate study viral pathogens, mutations, interactions various host proteins are essential. Viral replicon- virus-like particle (VLP)-based systems excellent examples tools. This review outlines importance, advantages, disadvantages both VLP-based have been developed SARS-CoV-2 helped scientific community in dimming intensity COVID-19 pandemic.

Language: Английский

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