Animals,
Journal Year:
2023,
Volume and Issue:
13(16), P. 2665 - 2665
Published: Aug. 18, 2023
Estimation
of
age
represents
a
central
focus
in
the
veterinary
forensic
pathology
field.
Currently,
visual
examination
dentition
and
skeletal
are
main
methods
to
estimate
puppies.
Nevertheless,
these
affected
by
broad
range
variables.
In
contrast,
kidney
is
characterized
specific
postnatal
development.
human
glomerulogenesis,
fetal
mesangial
cells
change
their
immunohistochemical
phenotypes
with
maturation.
Therefore,
we
hypothesized
that
histological
examinations
can
be
used
together
as
an
indirect
parameter
for
determination
puppies'
cadavers.
Forty-five
cadavers
were
divided
into
five
groups
defined
(Group
A=
0-15
days,
Group
B
=
16-45
C
46-85
D
86-105
E=
105-365
days).
For
each
case,
samples
collected
processed
histopathological
(for
morphometrical
study
glomerulus)
immunolocalization
α-SMA
protein)
studies.
Morphometrical
allowed
us
observe
statistical
differences
mean
glomerulus
numbers
per
field
among
assessed
groups.
Similarly,
showed
SMA
expression
Our
findings
suggest
potential
use
assess
illegally
imported
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 3, 2024
Abstract
Behavioral
dysfunctions
in
dogs
represent
one
of
the
main
social
concerns,
since
they
can
endanger
both
humans
and
animals.
Among
them,
phobia
is
usually
characterised
by
a
strong
persistent
fear
towards
something
that
might
feel
threatening,
including
thunderstorms,
fireworks,
strangers,
or
sounds.
Alongside
with
genetic
susceptibility,
environmental
factors,
traumatic
experiences,
medical
conditions
cause
dog
to
develop
such
psychiatric
disorders.
The
available
treatments
rely
on
behavioral
therapy,
based
cognitive-relational
approach,
associated
administration
drugs
acting
GABA,
serotonin
catecholamines.
Unfortunately,
pharmacological
interventions
are
hardly
effective
discourage
owners,
who
often
decide
relinquish
animals
shelters.
Recent
growing
evidence
highlight
importance
gut-brain
axis
modulation
brain
physiology
behavior.
Therefore,
present
study
we
sought
investigate
potential
connection
between
gut
microbiota
companion
dogs.
To
this
aim,
first
analyzed
faecal
samples
(total
n
=
16)
collected
from
mixed
breed
adult
(n
8/group).
Differentially
abundance
analysis
allowed
us
identify
taxa
related
Proteobacteria
Firmicutes
Phyla,
significantly
altered
phobic
In
addition,
metabolome
blood
serum
same
showed
significant
alterations
molecules
GABA
glutamate
neurotransmission,
as
well
bile
acids
metabolism.
Collectively,
our
preliminary
data
may
shed
light
combining
high-throughput
approaches
improve
diagnosis
aimed
at
counteracting
Animals,
Journal Year:
2023,
Volume and Issue:
13(16), P. 2665 - 2665
Published: Aug. 18, 2023
Estimation
of
age
represents
a
central
focus
in
the
veterinary
forensic
pathology
field.
Currently,
visual
examination
dentition
and
skeletal
are
main
methods
to
estimate
puppies.
Nevertheless,
these
affected
by
broad
range
variables.
In
contrast,
kidney
is
characterized
specific
postnatal
development.
human
glomerulogenesis,
fetal
mesangial
cells
change
their
immunohistochemical
phenotypes
with
maturation.
Therefore,
we
hypothesized
that
histological
examinations
can
be
used
together
as
an
indirect
parameter
for
determination
puppies'
cadavers.
Forty-five
cadavers
were
divided
into
five
groups
defined
(Group
A=
0-15
days,
Group
B
=
16-45
C
46-85
D
86-105
E=
105-365
days).
For
each
case,
samples
collected
processed
histopathological
(for
morphometrical
study
glomerulus)
immunolocalization
α-SMA
protein)
studies.
Morphometrical
allowed
us
observe
statistical
differences
mean
glomerulus
numbers
per
field
among
assessed
groups.
Similarly,
showed
SMA
expression
Our
findings
suggest
potential
use
assess
illegally
imported
