Progestogênios como contaminantes de preocupação emergente: persistência fotoquímica ambiental e alternativas de tratamento de efluentes farmacêuticos contaminados. DOI Creative Commons
Juliana Mendonça Silva de Jesus

Published: Feb. 13, 2023

Nesta Tese, foram investigadas as vias de entrada no meio ambiente que colaboram para a persistência fotoquímica ambiental dos progestogênios levonorgestrel (LNG) e gestodeno (GES) apresentadas alternativas remediação da fonte primária.Para tanto, inicialmente buscou-se avaliar degradação do LNG o GES sob luz solar simulada forma direta promovida por espécies reativas fotoinduzidas, empregando-se modelos cinéticos estimativa tempo meia-vida hormônios na água Reservatório Guarapiranga.Dada comprovação caráter persistente

Photoproduction of reactive intermediates from dissolved organic matter in coastal seawater around an urban metropolis in South China: Characterization and predictive modeling DOI
Yitao Li, Kai Zhang, Jennifer N. Apell

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 921, P. 170998 - 170998

Published: Feb. 15, 2024

Language: Английский

Citations

3

Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment DOI Creative Commons
Diana Ilyaskina, Yumi Nakadera, M.H. Lamoree

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 4, 2025

Pharmaceuticals such as selective serotonin reuptake inhibitors (SSRIs), are increasingly detected in aquatic environments, posing potential risks to non-target organisms, because many of those substances widely shared neuromodulator. In this study, we investigated the effects SSRI antidepressant, namely, fluoxetine, exposure on freshwater snail L. stagnalis , focusing egg development, neurochemical pathways, and lipid metabolism. Snails were exposed a range 51–434 µg fluoxetine L⁻ 1 for 7 days, followed by analysis survival, feeding behaviour, reproduction, metabolomic changes central nervous system (CNS), albumen gland, eggs. Although no significant observed survival or fecundity, significantly impaired development dose-dependent manner, reducing hatching rates with an EC50 126 . Removal eggs from contaminated environment partially reversed these developmental effects, suggesting recovery if levels decrease. Molecular revealed several lipidomic alterations. CNS, elevated catecholamines, phosphatidylcholines (PC), ceramides linked disruptions neurotransmission, membrane integrity, embryo development. decrease key classes, including sphingomyelins fatty acids, which can be quality. Additionally, histamine both gland suggested further disruption potentially affecting metamorphosis success. Moreover, increase choline, along PC oxidized PC, indicated oxidative stress peroxidation CNS Lymnaea Our findings highlight benefits combining behavioral assessments profiling better understand mechanistic pathways underlying fluoxetine’s adverse effects.

Language: Английский

Citations

0

Presence and Environmental Risk Assessment of Fluoxetine and Serotonin Hormone in the Istanbul Strait, Türkiye DOI
Güldehan Deryal, Nagihan E. Korkmaz, Abdullah Aksu

et al.

International Journal of Environmental Research, Journal Year: 2025, Volume and Issue: 19(3)

Published: Feb. 25, 2025

Language: Английский

Citations

0

Environmental Concentrations of Fluoxetine Antidepressant Affect Early Development of Sea Urchin Paracentrotus lividus DOI Creative Commons
Roberta Miroglio,

Roberta Nugnes,

L. Zanetti

et al.

Marine Environmental Research, Journal Year: 2025, Volume and Issue: 207, P. 107080 - 107080

Published: March 10, 2025

Fluoxetine (FLX), one of the most widely prescribed selective serotonin reuptake inhibitors, is frequently detected in aquatic environment. In this study we assessed ecotoxicological effects FLX on early life-stages sea urchin Paracentrotus lividus, a key species Mediterranean Sea. Fertilization rate, developmental anomalies and behavioural alterations were evaluated up to 72 h by exposing gametes, zygotes, embryos (gastrula) environmental (0.001, 0.01 mg/L) high concentrations (0.1, 1, 10 mg/L). Further, different types frequency morphological at larval level classified estimate Index Contaminant Impact (ICI) relevant concentrations. The ICI was applied predict which may pose risk urchins. Although did not affect fertilization, significant skeletal found plutei from each exposed stage. Based EC50 values, sensitivity ranks as follows: zygote > gastrula sperm. values indicated moderate impacts only However, slight impact also exposure concentrations, highlighting potential for development. Considering increasing consumption, suggest include PC monitoring plans, exceed levels that impair severely stages echinoderms. addition, our findings promote use novel tool assessment.

Language: Английский

Citations

0

Investigating fluoxetine removal via an electro-Fenton-like approach: Experimental design, kinetic modeling and evaluation of operating conditions DOI
Larissa Pinheiro de Souza,

Isabela Matos Gaudio de Souza,

Natalia Klanovicz

et al.

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 117370 - 117370

Published: June 1, 2025

Language: Английский

Citations

0

Effects of long-term fluoxetine exposure on morphology, but not behaviour or metabolic rate, in male guppies (Poecilia reticulata) DOI Creative Commons
Kate N. Fergusson,

James L. Tanner,

Jack A. Brand

et al.

Aquatic Toxicology, Journal Year: 2024, Volume and Issue: unknown, P. 107082 - 107082

Published: Sept. 1, 2024

Language: Английский

Citations

2

Environmental fate of methomyl pesticide in river water: Kinetic study, mathematical simulations and risk assessment DOI

Ádila de Oliveira Sampaio Dantas,

Matheus Larrondo Portiolli,

Larissa Pinheiro de Souza

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(2), P. 112157 - 112157

Published: Feb. 6, 2024

Language: Английский

Citations

1

Research on Micropollutants in Urban Water DOI Open Access
Cátia A. L. Graça

Water, Journal Year: 2023, Volume and Issue: 15(4), P. 644 - 644

Published: Feb. 7, 2023

To live in a safe and clean environment is right of every human being [...]

Language: Английский

Citations

2

Progestogênios como contaminantes de preocupação emergente: persistência fotoquímica ambiental e alternativas de tratamento de efluentes farmacêuticos contaminados. DOI Creative Commons
Juliana Mendonça Silva de Jesus

Published: Feb. 13, 2023

Nesta Tese, foram investigadas as vias de entrada no meio ambiente que colaboram para a persistência fotoquímica ambiental dos progestogênios levonorgestrel (LNG) e gestodeno (GES) apresentadas alternativas remediação da fonte primária.Para tanto, inicialmente buscou-se avaliar degradação do LNG o GES sob luz solar simulada forma direta promovida por espécies reativas fotoinduzidas, empregando-se modelos cinéticos estimativa tempo meia-vida hormônios na água Reservatório Guarapiranga.Dada comprovação caráter persistente

Citations

0