
Fisheries & Aquatic Life, Journal Year: 2024, Volume and Issue: 32(3), P. 128 - 136
Published: Sept. 1, 2024
Abstract This review paper presents fish reproductive toxicology studies with a specific focus on endocrine-disrupting chemicals (EDCs) present in the aquatic environment. These substances, including bisphenols, heavy metals, pesticides, phthalates, and polychlorinated biphenyls (PCBs), act as hormone mimics, receptor blockers, or enzyme inhibitors that affect hormonal regulation hypothalamic-pituitary-gonadal (HPG) axis. In this review, we provide an overview of adverse effects these pollutants both female male reproduction (i.e., disruption HPG axis, gametogenesis disorders, disturbed embryogenesis, etc.). Even at low concentrations, EDCs can exhibit toxicity fishes. They functioning certain systems within hypothalamus (Kiss/GPR54, GnRH) also impact luteinizing (LH) secretion pituitary. compounds have negative impacts gonads, oocyte maturation, steroidogenesis, gametes. Early-life exposure to substances not only affects embryonic development, resulting increased mortality body malformations, but induces genetic changes newly hatched larvae. All observations underscore need for monitoring environment implementing protective measures preserve health welfare fishes safeguard water ecosystems.
Language: Английский