ACS Applied Polymer Materials, Journal Year: 2025, Volume and Issue: unknown
Published: May 1, 2025
Language: Английский
Aggregate, Journal Year: 2024, Volume and Issue: 5(3)
Published: Jan. 4, 2024
Abstract Acute and infected wounds resulting from accidents, battlefield trauma, or surgical interventions have become a global healthcare burden due to the complex bacterial infection environment. However, conventional gauze dressings present insufficient contact with irregular lack antibacterial activity against multi‐drug‐resistant bacteria. In this study, we develop in situ nanofibrous tailored fit of various shapes sizes while providing nanoscale comfort excellent properties. Our approach involves fabrication these using handheld electrospinning device that allows for direct deposition nanofiber onto specific wound sites, perfect conformal closure without any mismatch 2 min. The are loaded multi‐armed antibiotics exhibit outstanding Staphylococcus aureus ( S. ) methicillin‐resistant . Compared vancomycin, dressing shows great performance up 98% vitro vivo experiments demonstrate ability prevent infection, greatly alleviate inflammation, promote healing. findings highlight potential personalized clinical applications, including emergency, accident, treatment.
Language: Английский
Citations
19
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 256, P. 128496 - 128496
Published: Nov. 29, 2023
Language: Английский
Citations
24
Soft Science, Journal Year: 2024, Volume and Issue: 4(1)
Published: Jan. 4, 2024
In the face of pandemic infectious diseases and increasing aging trends, traditional public health systems lack capacity for real-time monitoring, immediate clinical detection, continuous vital sign implementation long-cycle treatment protocols, among other deficiencies. On basis rapid development wearable electronic devices, Internet Things, artificial intelligence, future healthcare model will transform from a therapeutic, centralized, passive, even one-size-fits-all to new paradigm proactive, preventive, personalized, customized, intelligent way. The electronics has facilitated evolution biological enabling monitoring critical biomarkers diagnostic treatment, physiological assessment. Electronic textiles (e-textiles) are rapidly developing in recent years. They have revolutionized functionality by incorporating smart attributes, unique multifunctional applications. Significantly, e-textiles made notable advancements field personalized healthcare. article introduces several common their applications medicines, which also gives forward-looking outlook on growth diseases, preventive auxiliary therapy, rehabilitation training.
Language: Английский
Citations
15
Research, Journal Year: 2024, Volume and Issue: 7
Published: Jan. 1, 2024
Silica glass, known for its brittleness, weight, and non-biodegradable nature, faces challenges in finding suitable alternatives. Transparent wood, made by infusing polymers into shows promise but is hindered limited availability of wood China fire risks associated with use. This study explores the potential utilizing bamboo, which has a shorter growth cycle, as valuable resource developing flame-retardant, smoke-suppressing, superhydrophobic transparent bamboo. A 3-layered flame-retardant barrier, composed top silane layer, an intermediate layer SiO2 formed through hydrolysis-condensation Na2SiO3 on surface, inner Na2SiO3, been confirmed to be effective reducing heat release, slowing flame spread, inhibiting release combustible volatiles, toxic smoke, CO. Compared natural bamboo other congeneric products, displays remarkable superiority, majority parameters being notably lower entire order magnitude. It achieves long ignition time 116 s, low total (0.7 MJ/m2), smoke production (0.063 m2), peak CO concentration (0.008 kg/kg). Moreover, when used substrate perovskite solar cells, act light management leading marked efficiency enhancement 15.29%. The excellent features make it enticing choice future advancements glasses optical devices.
Language: Английский
Citations
15
International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 6(3), P. 032005 - 032005
Published: Feb. 22, 2024
Abstract Microfluidic devices are composed of microchannels with a diameter ranging from ten to few hundred micrometers. Thus, quite small (10 −9 –10 −18 l) amount liquid can be manipulated by such precise system. In the past three decades, significant progress in materials science, microfabrication, and various applications has boosted development promising functional microfluidic devices. this review, recent on novel functions is presented. First, theory numerical methods for studying performance briefly introduced. Then, fabrication summarized. Next, advances highlighted, including heat sinks, clean water production, chemical reactions, sensors, biomedicine, capillaric circuits, wearable electronic devices, microrobotics. Finally, perspectives challenges future developments This review aims inspire researchers fields—engineering, materials, chemistry, mathematics, physics, more—to collaborate drive forward specifically achieving carbon neutrality.
Language: Английский
Citations
15
Nano Materials Science, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Inspired by the skin structure, an asymmetric wettability tri-layer nanofiber membrane (TNM) consisting of hydrophilic inner layer loaded with lidocaine hydrochloride (LID), hydrophobic middle ciprofloxacin (CIP) and outer has been created. The endows TNM waterproof function anti-adhesion from contaminants. CIP preserves long-term inhibition bacteria growth LID possesses optimal water-absorbing capacity air permeability. dramatically elevates water contact angles 10° (inner layer) to 120° (outer layer), indicating wettability, which could directionally transport wound exudate within materials meanwhile maintain a comfortable moist environment promote healing. Furthermore, sequential release relieve pain rapidly achieve antibacterial effect in long run, respectively. In addition, shows superior biocompatibility towards L929 cells. vivo results show prevent infection, accelerate epithelial regeneration significantly This study indicates developed asymmetrical synergetic drug great potential as dressing clinical application.
Language: Английский
Citations
14
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 272, P. 132668 - 132668
Published: May 29, 2024
Language: Английский
Citations
12
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(27)
Published: July 7, 2024
Abstract The limited and unstable absorption of excess exudate is a major challenge during the healing infected wounds. In this study, highly stable, multifunctional Janus dressing with unidirectional transfer capacity fabricated based on single poly(lactide caprolactone) (PLCL). success method relies an acid hydrolysis reaction that transforms PLCL fibers from hydrophobic to hydrophilic in situ. resulting interfacial affinity between hydrophilic/phobic endows structure excellent liquid high structural stability against repeated stretching, bending, twisting. Various other functions, including wound status detection, antibacterial, antioxidant, anti‐inflammatory properties, are also integrated into by incorporating phenol red epigallocatechin gallate. An vivo methicillin‐resistant Staphylococcus aureus ‐infected model confirms dressing, capability remove site, not only facilitates epithelialization collagen deposition, but ensures low inflammation angiogenesis, thus reaching ideal closure rate up 98.4% day 14. simple structure, multiple easy fabrication may offer promising strategy for treating chronic wounds, rooted challenges bacterial infection, excessive exudate, persistent inflammation.
Language: Английский
Citations
10
Small, Journal Year: 2025, Volume and Issue: unknown
Published: March 5, 2025
To alleviate the discomfort caused by excessive sweating, there is a growing emphasis on developing wearable textiles that can evacuate sweat autonomously. These advanced fabrics, unlike their absorbent and retention-prone predecessors, harness Janus structure-distinguished its asymmetric wettability-to facilitate one-way transport of liquid. This unique characteristic has significant potential in addressing issues related to bodily moisture propelling realm smart wearables. review offers comprehensive overview advancements Janus-structured within field, delving into mechanisms behind unidirectional liquid transport, which rely chemical gradient curvature strategies, alongside methodologies for achieving wettability. It further spotlights multifaceted applications Janus-based wearables, including thermal management, wound care, analysis. In addition examining existing hurdles, also explores avenues future innovation, envisioning new era tailored personalized comfort health monitoring capabilities.
Language: Английский
Citations
1
Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(9)
Published: Nov. 27, 2023
Abstract A wearable sensor capable of directly detecting cytokines in external secretions to the human body is pivotal for gauging intensity immune response and circumventing inflammatory storms, a significant clinical concern. The detection low‐concentration often hampered due interference from impurities secretions. Addressing this challenge, system developed by integrating Janus membrane with water auto‐collection/filtering capabilities, aptamer‐modified graphene field‐effect transistor sensors, enabling undiluted sweat samples. can automatically filter transport them surface, effectively eliminating impurity enhancing sensor's capabilities. device sensitively detect (such as TNF‐α, marker inflammation cancer) sweat, range spanning 0.5 500 pM, limit reaching 0.31 pM. ultra‐flexibility also verified, maintaining stable electrical properties even after enduring up 50 extreme deformations. These findings indicate that has potential realize monitoring patients, assist healthcare controlling body's status.
Language: Английский
Citations
18