Harm Reduction Journal,
Journal Year:
2024,
Volume and Issue:
21(1)
Published: Nov. 5, 2024
The
substitution
of
cannabis
for
alcohol
and
other
drugs
has
been
conceptualised
in
a
harm
reduction
framework
as
where
is
used
to
reduce
the
negative
side-effects,
addiction
potential,
social
stigma
drugs.
There
currently
mixed
evidence
with
recent
reviews
suggesting
co-use
patterns
may
vary
by
age
ethnicity.
Yet
few
studies
have
had
large
enough
samples
examine
this
demographic
variation
detail.
To
explore
within
subgroups
sample
people
who
use
cannabis.
Specifically:
(1)
whether
being
substituted
drugs,
(2),
leads
more,
less
or
same
level
drug
use.
Online
convenience
survey
promoted
via
Facebook™
completed
23,500
New
Zealand
respondents.
Those
any
eight
substances
six-month
period
were
asked
if
their
impact
on
each
substance
("a
lot
more",
"little
"no
impact/same",
less",
"a
less").
Frequency
quantity
was
compared
group.
Generalised
logistic
regression
models
developed
predict
categories.
Significant
proportions
reported
led
"less"
(60%),
synthetic
cannabinoid
morphine
(44%)
methamphetamine
(40%)
using
lower
frequency
amount
Approximately
seven-out-ten
impact"
LSD,
MDMA,
cocaine
One-in-five
"more"
tobacco
Young
adults
(21–35-years)
more
likely
report
drinking
Adolescent
co-users
(16–20
years)
impacts.
Māori
resulted
alcohol,
tobacco,
methamphetamine,
LSD
Students
those
living
cities
lowering
substances.
Cannabis
are
moderated
life
stages,
lifestyles,
cultural
perspectives,
urbanicity.
Harm
initiatives
policy
reforms
should
take
account
these
moderating
factors.
American Journal of Public Health,
Journal Year:
2024,
Volume and Issue:
114(S8), P. S654 - S663
Published: Oct. 23, 2024
Objectives.
To
examine
whether
local
cannabis
policies
and
retail
availability
are
associated
with
use
problematic
(PCU)
among
adolescents
in
Northern
California.
Methods.
The
sample
comprised
aged
13
to
17
years
screened
for
past-year
during
well-child
visits
2021.
Exposures
included
bans
on
storefront
retailers,
policy
protectiveness,
proximity
density.
Outcomes
self-reported
PCU
diagnoses.
Modified
Poisson
regression
models
adjusted
sociodemographics.
Results.
(n
=
103
134)
was
51.1%
male
a
median
age
of
15
(interquartile
range
[IQR]
14–16
years);
5.5%
use,
0.3%
had
diagnosed
PCU.
Adolescents
lower
prevalence
jurisdictions
that
banned
retailers
(adjusted
rate
[APR]
0.857;
95%
confidence
interval
[CI]
0.814,
0.903
vs
allowed),
delivery
(APR
0.751;
CI
0.710,
0.795
or
more
protections
0.705–0.800).
Lower
also
found
those
(vs
allowed)
0.786;
0.629,
0.983)
0.783;
0.616,
0.996).
Longer
drive
time
density
were
prevalence.
Conclusions.
More
protective
less
adolescent
(
Am
J
Public
Health.
2024;114(S8):S654–S663.
https://doi.org/10.2105/AJPH.2024.307787
)
Journal of Psychopharmacology,
Journal Year:
2023,
Volume and Issue:
37(5), P. 462 - 471
Published: April 11, 2023
Background:
This
study
examined
changes
in
population-level
co-use
of
cannabis
and
alcohol
before
12
months
after
nonmedical
legalization
Canada,
relative
to
the
United
States
that
had
previously
legalized
not
(US
legal
illegal
states,
respectively).
Methods:
Data
are
from
waves
1
2
International
Cannabis
Policy
Study,
collected
2018
(before)
2019
(12
Canada).
Respondents
aged
16–65
years
Canada
(
n
=
25,313)
US
25,189)
19,626)
states
completed
an
online
survey.
Changes
between
compared
those
were
assessed
using
multinomial
logistic
regression.
Results:
Descriptive
analyses
show
increases
use
monthly
or
more
frequent
(MMF)
all
jurisdictions.
Compared
no
MMF
alcohol,
there
was
evidence
suggesting
differences
Canada.
However,
respondents
33%
higher
odds
alcohol-only
(OR
1.33,
99%
CI:
1.12,
1.57)
Conclusions:
Increases
observed
jurisdictions
regardless
status
cannabis.
These
shifts
largely
due
across
population,
including
may
indicate
changing
societal
norms
toward
generally.
As
transition
matures,
evaluation
over
longer
term
will
improve
understanding
influence
liberalization
on
co-use.
Journal of Studies on Alcohol and Drugs,
Journal Year:
2023,
Volume and Issue:
84(5), P. 734 - 743
Published: May 18, 2023
This
study
examined
whether
recreational
marijuana
legalization
(RML)
and
local
retail
availability
were
associated
with
alcohol
use
co-use
among
adolescents.
Drug Testing and Analysis,
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 30, 2024
Combined
use
of
alcohol
and
illicit
drugs
is
a
serious
health
social
problem.
In
this
study,
it
was
examined,
whether
relationship
between
drug
abuse
can
be
ascertained
by
comparison
marker
concentrations
in
hair.
the
frame
support
system
for
families
with
parental
drugs,
hair
samples
were
analyzed
2011
2022
methadone,
heroin
(6-acetylmorphine),
cocaine,
amphetamine,
ecstasy
(MDMA),
cannabinoids
(THC),
markers
ethyl
glucuronide
(EtG)
palmitate
(EtPa).
For
1314
from
adolescent
adult
family
members,
results
show
prevalence
combined
occasional
or
regular
abusive
41%-60%
except
(35%).
The
statistically
compared
three
categories
abstinence
moderate
drinking,
abuse.
most
frequently
detected
cocaine
(n
=
703),
significant
increase
rising
consumption
found.
frequent
detection
cocaethylene
proved
preferred
simultaneous
intake
both
substances.
THC
489),
no
difference
consumer
groups
seen.
Concerning
less
methadone
89),
6-acetylmorphine
92),
amphetamine
123),
MDMA
105),
clear
trend
determined.
It
concluded
that
evaluation
an
appropriate
way
to
study
extent
drug-alcohol
complements
other
studies
based
on
acquisition
data
interview
questionnaire.
Behavioral Sciences,
Journal Year:
2024,
Volume and Issue:
14(5), P. 407 - 407
Published: May 14, 2024
Alcohol
and
cannabis
use
are
each
associated
with
impairments
in
emotion
recognition
accuracy,
which
may
promote
interpersonal
problems.
It
is
unclear
if
or
self-reported
processing
differs
between
young
adult
alcohol
co-users
(ACCs)
healthy
controls
(HCs).
This
study
examined
whether
ACCs
HCs
differed
their
across
two
different
behavioral
tasks
static
dynamic
faces
determined
there
were
differences
socio-emotional
alexithymia.
22
(mean
age
=
21.27
±
1.75)
25
21.48
2.68),
matched
on
age,
sex,
IQ,
completed
the
Metrisquare
Emotion
Recognition
Task
CANTAB
Task.
The
compared
task
accuracy
measures,
including
Social
Emotional
Questionnaire
(SEQ)
Perth
Alexithymia
(PAQ).
No
significant
main
effects
of
Group
variable
Emotion-Group
interaction
present
for
either
task.
had
lower
SEQ
(
Drug and Alcohol Review,
Journal Year:
2023,
Volume and Issue:
43(3), P. 616 - 624
Published: April 24, 2023
Abstract
Introduction
In
the
21st
century,
there
has
been
a
decline
in
alcohol
use
among
adolescents
most
Nordic
countries,
while
trends
of
cannabis
have
diverged.
We
explore
how
and
use,
respectively,
co‐use
two
substances,
changed
adolescents.
Three
hypotheses
are
used
to
frame
study:
(i)
substituted
use;
(ii)
parallel
both
substances;
and/or
(iii)
‘hardening’
users,
implying
that
users
increasingly
cannabis.
Methods
Data
from
European
School
Survey
Project
on
Alcohol
Other
Drugs,
conducted
15‐
16‐year‐olds
Denmark,
Finland,
Iceland,
Norway
Sweden
(
N
=
74,700,
49%
boys),
were
past‐year
period
2003–2019.
Results
The
proportion
reporting
decreased
significantly
all
countries
except
Denmark.
those
using
only
was
low
(0.0%–0.7%)
stable
countries.
total
number
substance
occasions
declined
but
Among
became
prevalent
Discussion
Conclusions
found
no
support
for
‘parallel
hypothesis'
Partially
line
with
‘substitution
hypothesis’,
accounted
an
increasing
occasions.
Our
results
suggests
become
more
common,
thus
also
providing
hypothesis.
Alcohol research,
Journal Year:
2022,
Volume and Issue:
42(1)
Published: Jan. 1, 2022
Alcohol
is
frequently
used
in
association
with
cannabis,
co-use
now
perceived
as
normative
expanding
cannabis
legalization.Cannabinoid
products
are
increasingly
for
a
number
of
medical
and
recreational
purposes,
including
to
enhance
alcohol-reinforcing
properties
or
some
cases
substitute
alcohol.Rates
alcohol
use
disorder
(AUD)
higher
among
users
relative
nonusers,
approximately
60%
individuals
current
also
meeting
criteria
AUD.
1,2Co-use
linked
heavy
problematic
consumption,
which
turn
increases
risk
alcoholrelated
diseases
such
alcohol-associated
liver
disease.Co-use
negative
consequences,
behavioral
risks,
3
driving
safety,
psychiatric
comorbidity,
adverse
health
effects,
poor
treatment
outcomes.
4However,
the
impact
cannabinoids
on
alcohol-related
morbidity
not
well
understood,
findings
behaviors
equivocal.Cannabis
serves
both
complement
drinking
(i.e.,
increasing
use),
leading
more
harmful
effects
decreasing
minimizing
related
risks).
5Beyond
simultaneous
same-session)
temporally
independent
(e.g.,
same-week)
patterns,
substantial
variability
cannabinoid
composition
tetrahydrocannabinol
[THC]-to-cannabidiol
ratio),
formulations
smoked,
edibles),
quantity
could
influence
direction
effect
outcomes.Further,
individual
differences
associated
age
neurodevelopment;
substance
disorders;
6
motives
alcohol,
use;
7
statelevel
regulatory
policies
8
contribute
mixed
risks
benefits
relation
behaviors.This
research
review
series
approaches
cannabinoid-alcohol
through
lens
complex
interactions
between
biological,
psychological,
environmental
factors.Basic
science
reviewed
this
topic
highlights
role
endogenous
endocannabinoid
(eCB)
system
behaviors.The
eCB
system,
regulates
reinforcement,
involved
modulating
motivation
consume
excessive
AUD,
9-11
diseases.Emerging
preclinical
literature
implicates
exogenous
receptor
agonists
THC)
increased
chronic
exposure
implicated
disruptions
signaling.
12,13THC
primary
psychoactive
constituent
that
interacts
producing
intoxicating,
rewarding,
reinforcing
dose-dependent
function.Although
THC
most
commonly
studied
defines
potency,
there
than
100
other
phytocannabinoids
500
constituents
plant
may
exert
different
outcomes.For
example,
cannabidiol
(CBD)
nonpsychoactive,
plant-based
has
been
medicinal
value