ASSISTÊNCIA FARMACÊUTICA NA ADESÃO AO TRATAMENTO ANTIRRETROVIRAL: UMA REVISÃO SISTEMÁTICA E META-ANÁLISE

Revista Foco, Journal Year: 2025, Volume and Issue: 18(3), P. e8122 - e8122

Published: March 31, 2025

A adesão ao tratamento antirretroviral (TARV) é crucial para o controle do HIV, e a assistência farmacêutica desempenha um papel essencial na melhoria dessa adesão, favorecendo eficácia qualidade de vida dos pacientes. O objetivo deste estudo analisar como influencia TARV em pacientes com por meio uma revisão sistemática da literatura. foi conduzida nas bases dados LILACS, Medline (PubMed), Center for Reviews and Dissemination (CRD), The Cochrane Library Trip Medical Database. Foram considerados estudos publicados nos últimos 10 anos. análise realizada através software Review Manager 5.4, gerando gráficos Forest Plot avaliação risco viés. Sete estudos, 1.131 participantes, foram incluídos revisão. teve impacto positivo TARV, melhorias no viral, redução eventos adversos. maioria das intervenções colaboração outros profissionais saúde, potencializando os resultados. Esta proporciona evidências que podem orientar aprimoramento práticas cuidado gestão direto tratamentos.

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Estudio cualitativo sobre la adopción y puesta en valor del modelo capacidad-motivación-oportunidad de atención farmacéutica en las consultas externas de farmacia en España

Farmacia Hospitalaria, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

To analyse and address the barriers that Pharmacy Services encounter when adopting capacity-motivation-opportunity (CMO) pharmaceutical care model in outpatient consultations, identifying relevant actors ecosystem, as well motivations. Finally, to make a first approach solutions will help us select those could be developed through future initiatives. A structured methodology was several phases. Two teams were formed: "Core Team," consisting of hospital pharmacists with experience patient-centered care, "Guiding made up professionals from various disciplines. The phase included an online prospecting workshop explore phases adoption. Subsequently, semi-structured interviews conducted key actors, such physicians, managers, patient associations, identify needs barriers. face-to-face organized facilitate ideation validation solutions. Three categories CMO ecosystem identified: interested agents (beneficiaries), interesting (influencers), executive (implementers). Significant found, including variability infrastructure, lack commitment workload pharmacists. However, there also growing motivation among organizations adopt model. During workshop, ten initiatives prioritized, use digital technologies ongoing training programs. study highlights high potential improve settings Spain, despite identified proposed strategies, focused on digitalization multidisciplinary collaboration, are essential for effective implementation. Future research is suggested evaluate long-term impact these strengthen involvement associations other adoption process.

Language: Английский

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[Translated article] Prioritisation of 2024–2027 initiatives of the strategic Map for outpatient pharmaceutical care of the Spanish Society of Hospital Pharmacy

Farmacia Hospitalaria, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

To prioritise the initiatives to be developed for development of Strategic Map Outpatient Care (MAPEX) project improve quality care and pharmaceutical patients seen in hospital pharmacy outpatient clinics period 2024-2027 Spain.

Language: Английский

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Priorización de iniciativas 2024–2027 del mapa estratégico de atención farmacéutica al paciente externo de la Sociedad Española de Farmacia Hospitalaria

Farmacia Hospitalaria, Journal Year: 2024, Volume and Issue: unknown

Published: April 1, 2024

To prioritize the initiatives to be developed for development of Strategic Map Outpatient Care (MAPEX) project improve quality care and Pharmaceutical patients seen in Hospital Pharmacy outpatient clinics period 2024-2027 Spain.

Language: Английский

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Influence of the type of antiretroviral treatment on the time to reach high pharmacotherapy complexity in people living with HIV

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: June 4, 2024

Background: The primary objective was to assess the impact of antiretroviral treatment (ARV) on duration required achieve a high medication regimen complexity index (MRCI) in people living with HIV (PLWH). Methods: A single-centre observational analytical research study conducted, including adult PLWH ARV from January 2010 December 2022, who were treated hospital pharmacy. An analysis time reach MRCI value ≥11.25 performed, followed by Cox regression model determine influence pharmacotherapeutic complexity. Results: total 789 included, medium age 52 years (interquartile range: 45-58 years). Overall, 195 patients had an mean it 181.86 months (95%CI: 176.24 - 187.49 months). Significant differences observed sex, advanced age, AIDS stage, presence comorbidities, polypharmacy, and ARV-related variables. multivariate proportional hazards showed that INSTI-containing regimens (HR: 1.83; 95CI: 1.08-3.10) NNRTI-based 0.72; 0.52-0.98) influenced until reached. Conclusions: In summary, composed 2 NRTI + NNRTI protective effect development compared INSTI, which is identified as risk factor. These conclusions derived patient profile included prevalence both comorbidities polypharmacy. Therefore, identifying allows us implement optimization strategies improve your health outcomes.

Language: Английский

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Un cuarto de siglo del grupo VIH-SEFH: transformando la atención, afrontando retos y reafirmando el compromiso

Farmacia Hospitalaria, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

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Influence of the Type of Antiretroviral Treatment on the Time to Reach High Pharmacotherapy Complexity in People Living With HIV

Annals of Pharmacotherapy, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 23, 2024

Background: The introduction of antiretroviral therapy (ARV) has significantly improved the survival people living with HIV (PLWH), increasing proportion individuals over 50 years old. This aging trend poses challenges, such as development age-related comorbidities and a higher prevalence polypharmacy. pharmacotherapeutic complexity, assessed using Medication Regimen Complexity Index (MRCI), is crucial for identifying optimizing treatment, especially in elderly polymedicated patients. Objective: main objective was to assess association between different ARV regimens time required reach high level complexity PLWH. Methods: A single-center observational analytical research study conducted, including adult PLWH on active from January 2010 December 2021 follow-up until 2023. An analysis MRCI ≥11.25 performed, followed by Cox regression model determine influence MRCI. Results: total 789 were included, median age 52 (interquartile range: 45-58). Overall, 195 patients had an value mean it 181.86 months (95% confidence interval [CI]: 176.24 187.49). Significant differences observed sex, advanced age, AIDS stage, presence comorbidities, polypharmacy, ARV-related variables. multivariate proportional hazards showed integrase inhibitor (INSTI)-containing (hazard ratio [HR]: 1.83; 95% CI: 1.08 3.10) non-nucleoside reverse transcriptase (NNRTI)-based (HR: 0.72; 0.52 0.98) Conclusions Relevance: In summary, NNRTI-based associated lower likelihood developing compared INSTI-based regimens, which likelihood. These conclusions are based profile that included Identifying may help us implement optimization strategies improve health outcomes.

Language: Английский

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[Translated article] A quarter of a century of the VIH-SEFH group: Transforming care, facing challenges and reaffirming commitment

Farmacia Hospitalaria, Journal Year: 2024, Volume and Issue: 48(6), P. T263 - T264

Published: Nov. 1, 2024

Language: Английский

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