Cancers,
Journal Year:
2023,
Volume and Issue:
15(22), P. 5476 - 5476
Published: Nov. 20, 2023
Objectives:
We
aimed
to
develop
a
novel
non-linear
statistical
model
integrating
primary
tumor
features
on
baseline
[18F]-fluorodeoxyglucose
positron
emission
tomography/computed
tomography
(FDG-PET/CT),
molecular
subtype,
and
clinical
data
for
treatment
benefit
prediction
in
women
with
newly
diagnosed
breast
cancer
using
innovative
techniques,
as
opposed
conventional
methodological
approaches.
Methods:
In
this
single-center
retrospective
study,
we
conducted
comprehensive
assessment
of
who
had
undergone
FDG-PET/CT
scan
staging
prior
treatment.
Primary
(PT)
volume,
maximum
mean
standardized
uptake
value
(SUVmax
SUVmean),
metabolic
volume
(MTV),
total
lesion
glycolysis
(TLG)
were
measured
PET/CT.
Clinical
including
(TNM)
but
also
PT
anatomical
site,
histology,
receptor
status,
proliferation
index,
subtype
obtained
from
the
medical
records.
Overall
survival
(OS),
progression-free
(PFS),
(CB)
assessed
endpoints.
A
logistic
generalized
additive
was
chosen
approach
assess
impact
all
listed
variables
CB.
Results:
70
(mean
age
63.3
±
15.4
years)
included.
The
most
common
location
upper
outer
quadrant
(40.0%)
left
(52.9%).
An
invasive
ductal
adenocarcinoma
(88.6%)
high
index
ki-67
expression
35.1
24.5%)
B
(51.4%)
by
far
detected
tumor.
Most
PTs
displayed
hybrid
imaging
greater
(12.8
30.4
cm3)
hypermetabolism
SD
SUVmax,
SUVmean,
MTV,
TLG,
respectively:
8.1
7.2,
4.9
4.4,
12.7
30.4,
47.4
80.2).
Higher
(p
<
0.01),
SUVmax
=
0.04),
SUVmean
0.03),
MTV
(<0.01)
significantly
compromised
considerable
majority
patients
survived
throughout
period
(92.8%),
while
five
died
(7.2%).
fact,
OS
31.7
14.2
months
PFS
30.2
14.1
months.
multivariate
CB
excellent
accuracy
could
be
developed
age,
body
mass
(BMI),
T,
M,
predictive
parameters.
TLG
demonstrated
significant
influence
lower
ranges;
however,
beyond
specific
cutoff
(respectively,
29.52
cm3
161.95
TLG),
their
only
reached
negligible
levels.
Ultimately,
absence
distant
metastasis
M
strong
positive
ahead
size
T
(standardized
average
estimate
0.88
vs.
0.4).
Conclusions:
Our
results
emphasized
pivotal
role
played
forecasting
outcomes
cancer.
Nevertheless,
careful
consideration
is
required
when
selecting
approach,
our
techniques
unveiled
influences
biomarkers
benefit,
highlighting
importance
early
diagnosis.
Polish Journal of Radiology,
Journal Year:
2025,
Volume and Issue:
90, P. 1 - 8
Published: Jan. 21, 2025
Purpose
Early
detection
of
breast
cancer
is
crucial
for
improving
patient
outcomes.
With
advancements
in
artificial
intelligence
(AI),
there
growing
interest
its
potential
to
assist
radiologists
interpreting
mammograms
early
detection.
AI
algorithms
offer
the
promise
increased
accuracy
and
efficiency
identifying
subtle
signs
cancer,
potentially
complementing
expertise
enhancing
screening
process
early-stage
Material
Methods
A
systematic
literature
review
was
conducted
identify
select
original
research
reports
on
diagnosis
by
versus
conventional
using
accordance
with
PRISMA
guidelines.
Data
were
analysed
Review
Manager
version
5.4.
<i>P</i>-value
<i>I<sup>2</sup></i>
used
test
significance
differences.
Results
This
meta-analysis
included
8
studies
data
from
a
total
120,950
patients.
Regarding
sensitivity
AI,
pooled
analysis
6
sensitivities
ranging
0.70
0.89
yielded
0.85.
However,
ranged
0.63
0.85,
an
overall
0.77.
As
specificity,
both
groups
had
closer
results.
Conclusions
The
comparison
between
systems
detecting
highlights
as
valuable
tool
screening.
While
have
shown
promising
results
terms
efficiency,
they
should
be
viewed
complementary
rather
than
replacements.
npj Imaging,
Journal Year:
2025,
Volume and Issue:
3(1)
Published: April 9, 2025
Given
the
enormous
output
and
pace
of
development
artificial
intelligence
(AI)
methods
in
medical
imaging,
it
can
be
challenging
to
identify
true
success
stories
determine
state-of-the-art
field.
This
report
seeks
provide
magnetic
resonance
imaging
(MRI)
community
with
an
initial
guide
into
major
areas
which
AI
are
contributing
MRI
oncology.
After
a
general
introduction
intelligence,
we
proceed
discuss
successes
current
limitations
when
used
for
image
acquisition,
reconstruction,
registration,
segmentation,
as
well
its
utility
assisting
diagnostic
prognostic
settings.
Within
each
section,
attempt
present
balanced
summary
by
first
presenting
common
techniques,
state
readiness,
clinical
needs,
barriers
practical
deployment
setting.
We
conclude
new
advances
must
realized
address
questions
regarding
generalizability,
quality
assurance
control,
uncertainty
quantification
applying
cancer
maintain
patient
safety
utility.
BMC Cancer,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 15, 2025
Cancer
remains
a
significant
health
challenge
in
the
ASEAN
region,
highlighting
need
for
effective
screening
programs.
However,
approaches,
target
demographics,
and
intervals
vary
across
member
states,
necessitating
comprehensive
understanding
of
these
variations
to
assess
program
effectiveness.
Additionally,
while
artificial
intelligence
(AI)
holds
promise
as
tool
cancer
screening,
its
utilization
region
is
unexplored.
This
study
aims
identify
evaluate
different
programs
ASEAN,
with
focus
on
assessing
integration
impact
AI
A
scoping
review
was
conducted
using
PRISMA-ScR
guidelines
provide
overview
usage
ASEAN.
Data
were
collected
from
government
ministries,
official
guidelines,
literature
databases,
relevant
documents.
The
use
reviews
involved
searches
through
PubMed,
Scopus,
Google
Scholar
inclusion
criteria
only
included
studies
that
utilized
data
January
2019
May
2024.
findings
reveal
diverse
approaches
Countries
like
Myanmar,
Laos,
Cambodia,
Vietnam,
Brunei,
Philippines,
Indonesia
Timor-Leste
primarily
adopt
opportunistic
Singapore,
Malaysia,
Thailand
organized
Cervical
widespread,
both
methods.
Fourteen
review,
covering
breast
(5
studies),
cervical
(2
colon
(4
hepatic
(1
study),
lung
oral
study)
cancers.
Studies
revealed
stages
screening:
prospective
clinical
evaluation
(50%),
silent
trial
(36%)
exploratory
model
development
(14%),
promising
results
enhancing
accuracy
efficiency.
require
more
targeting
appropriate
age
groups
at
regular
meet
WHO's
2030
targets.
Efforts
integrate
Thailand,
show
optimizing
processes,
reducing
costs,
improving
early
detection.
technology
enhances
identification
during
detection
management
region.
Oxford University Press eBooks,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 20, 2025
Abstract
An
urgent
need
exists
to
define
comprehensive
ethical
and
operational
frameworks
designed
address
gender
bias
in
artificial
intelligence–driven
health
applications
within
unique
healthcare
environments
of
Africa.
These
would
the
critical
challenge
disparities
that
exist
AI
systems,
which
can
worsen
outcomes
for
women.
This
article
outlines
proactive
approaches
mitigate
deployed
African
settings.
It
expands
on
complexities
surrounding
consent
deployment
highlights
transparency
about
AI’s
role
patient
care
strict
data
governance
policies
are
sensitive
vulnerabilities
The
examines
key
challenges
related
technologies
how
existing
may
not
be
suited
context.
With
this
background,
it
advocates
gender-sensitive
gender-transformative
design
frameworks,
mandating
multidisciplinary
teams
with
studies,
Afro-feminist
expertise.
Additionally,
collected
from
FemTech
Africa
offer
complementary
solutions
by
integrating
into
systems
improve
accuracy
inclusivity.
also
draws
attention
gender-differentiated
datasets
ensure
algorithms
trained
context-specific
data.
further
proposes
establishment
oversight
committees
strong
representation
deep
expertise
ethics.
enforce
compliance
standards
promote
accountability.
If
efforts
made
biases
implementation
these
have
potential
contribute
improved
However,
impact
depends
responsible
development
AI,
robust
governance,
consideration
local
contexts.
Scholars Academic Journal of Pharmacy,
Journal Year:
2024,
Volume and Issue:
13(02), P. 67 - 81
Published: Feb. 28, 2024
Artificial
Intelligence
(AI)
is
revolutionizing
healthcare
by
transforming
disease
identification,
treatment,
and
management.
Healthcare
organizations
are
rapidly
adopting
AI
technologies
to
improve
patient
outcomes,
streamline
operations,
optimize
costs.
Utilizing
a
broad
toolkit
comprising
Robotics,
Computer
Vision,
Natural
Language
Processing,
Machine
Learning,
has
made
significant
advancements
across
various
domains.
AI-driven
diagnostic
systems
showcased
for
their
precision
in
analyzing
medical
images,
enabling
early
detection
of
diseases
such
as
cancer.
Personalized
treatment
plans
preventive
treatments
possible
predictive
analytics,
which
uses
large
amounts
data
predict
the
course
identify
those
who
at
risk.
This
leads
an
improvement
care.
Beyond
clinical
applications,
reshaping
delivery
through
solutions
like
telemedicine,
virtual
consultations,
remote
monitoring.
Virtual
Health
Assistants,
empowered
AI,
deliver
personalized
health
information,
medication
reminders,
lifestyle
guidance,
enhancing
engagement
adherence.
Telemedicine
employ
algorithms
enhance
resource
allocation,
expedite
appointment
scheduling,
supply
superior
services
isolated
populations.
Hence,
AI’s
potential
productivity,
encourage
creativity,
solve
difficult
problems
sophisticated
analysis
automation
what
it
so
important
many
sectors.
Current Medical Imaging Formerly Current Medical Imaging Reviews,
Journal Year:
2024,
Volume and Issue:
20
Published: March 1, 2024
Objective::
This
study
evaluates
the
effectiveness
of
artificial
intelligence
(AI)
in
mammography
a
diverse
population
from
middle-income
nation
and
compares
it
to
traditional
methods.
Methods::
A
retrospective
was
conducted
on
543
mammograms
467
Malays,
48
Chinese,
28
Indians
nation.
Three
breast
radiologists
interpreted
examinations
independently
two
reading
sessions
(with
without
AI
support).
Breast
density
BI-RADS
categories
were
assessed,
comparing
accuracy,
sensitivity,
specificity,
positive
predictive
value
(PPV),
negative
(NPV)
results.
Results::
Of
mammograms,
69.2%
had
lesions
detected.
Biopsies
performed
25%(n=136),
with
66(48.5%)
benign
70(51.5%)
malignant.
Substantial
agreement
assessment
between
radiologist
software
(κ
=0.606,
p
<
0.001)
category
=0.74,
0.001).
The
performance
comparable
PPV,
NPV
or
alone,
+
AI,
alone
81.9%,90.4%,56.0%,
97.1%;
81.0%,
93.1%,55.5%,
97.0%;
90.0%,76.5%,36.2%,
98.1%,
respectively.
enhances
accuracy
lesion
diagnosis
reduces
unnecessary
biopsies,
particularly
for
4
lesions.
results
synthetic
almost
similar
original
2D
mammography,
AUC
0.925
0.871,
Conclusion::
may
assist
accurate
lesions,
enhancing
efficiency
mixed
opportunistic
screening
diagnostic
patients.
Key
Messages::
•
use
population-based
cancer
has
been
validated
high-income
nations,
reported
improved
performance.
Our
evaluated
usage
an
tool
setting
multi-ethnic
application
potentially
leading
reduced
biopsies.
integration
into
workflow
did
not
disrupt
trained
radiologists,
as
there
is
substantial
inter-reader
density.
Magnetic Resonance Imaging,
Journal Year:
2024,
Volume and Issue:
113, P. 110214 - 110214
Published: July 22, 2024
The
research
aimed
to
determine
whether
and
which
radiomic
features
from
breast
dynamic
contrast
enhanced
(DCE)
MRI
could
predict
the
presence
of
BRCA1
mutation
in
patients
with
triple-negative
cancer
(TNBC).
This
retrospective
study
included
consecutive
histologically
diagnosed
TNBC
who
underwent
DCE-MRI
2010–2021.
Baseline
DCE-MRIs
were
retrospectively
reviewed;
percentage
maps
wash-in
wash-out
computed
lesions
manually
segmented,
drawing
a
5
mm-Region
Interest
(ROI)
inside
tumor
another
mm-ROI
contralateral
healthy
gland.
Features
for
each
map
ROI
extracted
Pyradiomics-3D
Slicer
considered
first
separately
(tumor
gland)
then
together.
In
analysis
more
important
status
classification
selected
Maximum
Relevance
Minimum
Redundancy
algorithm
used
fit
four
classifiers.
population
67
86
(21
BRCA1-mutated,
65
non
BRCA-carriers).
best
classifiers
BRCA
Support
Vector
Classifier
Logistic
Regression
models
fitted
both
gland
features,
reaching
an
Area
Under
ROC
Curve
(AUC)
0.80
(SD
0.21)
0.79
0.20),
respectively.
Three
higher
BRCA1-mutated
compared
BRCA-mutated:
Total
Energy
Correlation
gray
level
cooccurrence
matrix,
measured
maps,
Root
Mean
Squared,
tumor.
showed
feasibility
potential
radiomics
predicting
mutational
status.
Journal of radiology and nuclear medicine,
Journal Year:
2023,
Volume and Issue:
104(2), P. 151 - 162
Published: Aug. 7, 2023
The
relevance
of
implementing
artificial
intelligence
(AI)
technologies
in
the
diagnosis
breast
cancer
(BC)
is
associated
with
a
continuing
high
increase
BC
incidence
among
women
and
its
leading
position
structure
incidence.
Theoretically,
using
AI
possible
both
at
stage
screening
clarifying
diagnosis.
article
provides
brief
overview
systems
used
clinical
practice
discusses
their
prospects
Advances
machine
learning
can
be
effective
to
improve
accuracy
mammography
by
reducing
missed
cases
false
positives.
Critical Reviews™ in Oncogenesis,
Journal Year:
2023,
Volume and Issue:
29(2), P. 15 - 28
Published: Sept. 18, 2023
Breast
ultrasound
has
emerged
as
a
valuable
imaging
modality
in
the
detection
and
characterization
of
breast
lesions,
particularly
women
with
dense
tissue
or
contraindications
for
mammography.
Within
this
framework,
artificial
intelligence
(AI)
garnered
significant
attention
its
potential
to
improve
diagnostic
accuracy
revolutionize
workflow.
This
review
article
aims
comprehensively
explore
current
state
research
development
harnessing
AI's
capabilities
ultrasound.
We
delve
into
various
AI
techniques,
including
machine
learning,
deep
well
their
applications
automating
lesion
detection,
segmentation,
classification
tasks.
Furthermore,
addresses
challenges
hurdles
faced
implementing
systems
diagnostics,
such
data
privacy,
interpretability,
regulatory
approval.
Ethical
considerations
pertaining
integration
clinical
practice
are
also
discussed,
emphasizing
importance
maintaining
patient-centered
approach.
The
holds
great
promise
improving
accuracy,
enhancing
efficiency,
ultimately
advancing
patient's
care.
By
examining
identifying
future
opportunities,
contribute
understanding
utilization
encourage
further
interdisciplinary
collaboration
maximize
practice.