Deleted Journal, Journal Year: 2024, Volume and Issue: 31(6), P. 1043 - 1056
Published: Dec. 1, 2024
The objective of this study was to identify functional materials with potential benefits for digestive enzyme activity, anti-inflammatory effects, and antioxidant activity. evaluated water extracts from Pyrus pyrifolia Nakai (PP), malt (MA), Ziziphus jujuba Mill. (ZJ), Leonurus japonicus Houtt. (LJ), Scutellaria baicalensis (SB), various mixtures these. These were concentrated, lyophilized, labeled as PPW, MAW, ZJW, LJW, SBW, Mix1, Mix2, Mix3, Mix4, Mix5. Among all the samples tested, composed PP, MA, ZJ, LJ, SB in a ratio 1:1:2:1:2 (w/w), showed most promising results. It exhibited highest DPPH radical scavenging activity at concentration 1,000 μg/mL. Mix3 total polyphenol content compared other mixtures. also assessed effects by measuring levels nitric oxide (NO) tumor necrosis factor-alpha (TNF-α) lipopolysaccharide (LPS)-stimulated Caco-2 cells. found suppress production both NO TNF-α significantly. Additionally, evaluated. demonstrated superior lipase α-amylase activities 100 μg/mL, well comparable or higher trypsin 500 μg/mL when extracts. findings suggest that enhances effect, making it material improving digestion.
Language: Английский