Role of Helicobacter pylori infection and the risk of cholelithiasis DOI
Nicolò Fabbri, Salvatore Greco, Antonio Pesce

et al.

World Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: 31(8)

Published: Jan. 23, 2025

This article aims to deepen the understanding of role Helicobacter pylori (H. ) infection in development cholelithiasis, initiated by Yao et al , who investigated potential link between H. and cholelithiasis through a multicenter retrospective study on an Asian population over 70000 participants. They also performed comprehensive analysis previously published studies finding positive association therein [odds ratio (OR) = 1.103, P 0.049]. Patients for had lower levels total direct bilirubin, but higher cholesterol low-density lipoprotein compared uninfected patients (P < 0.05). Cohort have confirmed that is risk factor 0.0001), aggregate analyses case-control cross-sectional shown Asia (OR 1.599, 0.034), not Europe 1.277, 0.246). Moreover, appears be related choledocholithiasis/cholecystolithiasis 3.321, 0.033). The authors conclude positively correlated with particularly choledocholithiasis phenotype, especially Asia, it potentially bilirubin metabolism.

Language: Английский

Role of Helicobacter pylori infection and the risk of cholelithiasis DOI
Nicolò Fabbri, Salvatore Greco, Antonio Pesce

et al.

World Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: 31(8)

Published: Jan. 23, 2025

This article aims to deepen the understanding of role Helicobacter pylori (H. ) infection in development cholelithiasis, initiated by Yao et al , who investigated potential link between H. and cholelithiasis through a multicenter retrospective study on an Asian population over 70000 participants. They also performed comprehensive analysis previously published studies finding positive association therein [odds ratio (OR) = 1.103, P 0.049]. Patients for had lower levels total direct bilirubin, but higher cholesterol low-density lipoprotein compared uninfected patients (P < 0.05). Cohort have confirmed that is risk factor 0.0001), aggregate analyses case-control cross-sectional shown Asia (OR 1.599, 0.034), not Europe 1.277, 0.246). Moreover, appears be related choledocholithiasis/cholecystolithiasis 3.321, 0.033). The authors conclude positively correlated with particularly choledocholithiasis phenotype, especially Asia, it potentially bilirubin metabolism.

Language: Английский

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