European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 30, 2024
Abstract The X−H insertion reaction (X=heteroatom) of diazo compounds has emerged as an eminent and reliant approach for the construction C−X bonds. By merging with sequential ring‐closing transformations, diverse heterocyclic systems can be obtained in a step‐economical manner. In recent years, insertion/cyclization cascades one‐pot transformations attract more research attention, especially area asymmetric synthesis. Concentrating on assembly N,O,S‐heterocycles, this Concept elucidates various combinations reactions cyclization via addition to multiple ring‐forming strategies reviewed comprise Michael‐type Conia‐ene reactions, aldol condensation, Mannich reaction.
Language: Английский