Beilstein Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 20, P. 2704 - 2707
Published: Oct. 28, 2024
Language: Английский
Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(40)
Published: May 14, 2024
The regiodivergent synthesis of 4- and 5-sulfenyl oxazoles from 1,4,2-dioxazoles alkynyl thioethers has been achieved. Gold-catalysed conditions are used to favour the formation via β-selective attack nitrenoid relative sulfenyl group. In contrast, 4-sulfenyl formed by α-selective reaction under Brønsted acid same substrates. nature stabilising gold-sulfur interactions have investigated natural bond orbital analysis, showing that S→Au significantly stronger in intermediate favours oxazoles. A kinetic survey identifies catalyst inhibition processes. This study into methods includes development telescoped annulation-oxidation protocols for regioselective access oxazole sulfoxides sulfones.
Language: Английский
Citations
3
Beilstein Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 20, P. 2704 - 2707
Published: Oct. 28, 2024
Language: Английский
Citations
0