Neuroscience-Driven Solutions for Speech Impairment

Advances in medical education, research, and ethics (AMERE) book series, Journal Year: 2025, Volume and Issue: unknown, P. 119 - 146

Published: Jan. 10, 2025

Speech impairment presents a significant challenge for aged and chronically ill individuals. Emerging assistive technologies offer promising solutions to improve their communication abilities. This discussion explores established options like Augmentative Alternative Communication (AAC) devices cutting-edge approaches Brain-Computer Interfaces (BCIs). Neuroprosthetics, field merging neuroscience biomedical engineering, aims replace or modulate damaged parts of the nervous system. We delved into potential optogenetics, neuroengineering devices, biosensors, highlighting contributions future advancements in speech assistance. The dialogue emphasized importance comprehensive approach, combining with ongoing research on areas synthetic biology. multi-faceted approach holds key empowering speech-impaired individuals fostering improved communication.

Language: Английский

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Spatially Variable Genes

Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 28

Published: Dec. 17, 2024

The clinical translation of spatial transcriptomics represents cancer diagnosis and therapy based on the role heterogeneity cancer-associated fibroblasts (CAFs) within tumor microenvironment (TME). Recent developments in have enabled a detailed characterization organization cellular interactions tumors. data integration, multi-omics approaches, along with developing standardized protocols is essential for effective translation. experimental selection regimes factorial designs reveals novel insights into biomarkers prognostic value CAFs. incorporation optogenetics advancements bio-engineered gene circuits, therapeutics tissue engineering further underscores potential to refine patient stratification improve treatment responsiveness. By integrating workflows, this work aims advance personalized therapies biology.

Language: Английский

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Spatial Omics and Gene Circuits

Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2024, Volume and Issue: unknown, P. 383 - 408

Published: Dec. 17, 2024

Spatial transcriptomics is a powerful tool in biomedical research that enables the analysis of gene expression patterns within their spatial context. By providing insights into organisation expression, this technology can help address limitations design synthetic circuits controlled manner. In cancer biology, combining with other approaches allows researchers to gain deeper understanding spatiotemporal dynamics regulation. This method has significant potential for revealing tissue architecture and cellular heterogeneity, which complements circuits. study explores advantages circuit analysis, focusing on integrating these techniques understand better temporal regulation genes tissues.

Language: Английский

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Synthetic Biology and AI

Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2024, Volume and Issue: unknown, P. 265 - 290

Published: Dec. 17, 2024

Synthetic biology and artificial intelligence are ushering in a new era of healthcare. In the specific context bioengineering, organoids, brain-computer interfaces, ethical considerations particularly salient. Challenges such as data inadequacy, unintended bias can undermine reliability fairness decision making. Additionally, cultural barriers concerns related to nonmaleficence, autonomy, justice must be carefully considered. To fully realize benefits this technological synergy, multidisciplinary approach is necessary, involving scientists, engineers, ethicists, policymakers. Transparent accountable AI systems essential mitigate biases, protect privacy, avoid consequences. By proactively addressing developing robust regulatory frameworks, we harness power these technologies for betterment humanity.

Language: Английский

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