Cascade of care for people with positive symptoms of common cancers in selected primary health centres of Puducherry: An explanatory mixed-method study DOI Open Access
Srijeeta Mitra, Swaroop Kumar Sahu, Subitha Lakshminarayanan

et al.

The Indian Journal of Medical Research, Journal Year: 2024, Volume and Issue: 160, P. 457 - 465

Published: Dec. 20, 2024

Background & objectives Cancer is a leading cause of death worldwide and constitutes public health priority. Delays in diagnosis treatment cancer can adversely impact survival, recovery, cost treatment. The objective this study was to estimate the proportion seeking timely care among those having early warning signals for oral, breast or cervical explore facilitators barriers detection. Methods conducted 241 participants, including selected cancers women who underwent opportunistic screening facilities. Information regarding symptom appearance, presentation any registered medical practitioner, confirmatory diagnosis, initiation were obtained from records. In-depth Interviews (IDIs) six participants Results Among 7300 people screened using Community Based Assessment Checklist (CBAC), 128 (1.7%) had one cancers. percentage sought symptoms 80 per cent, 82 cent 57 respectively. centres (113), screen positivity rate 11 adherence referral confirmation cent. median pre-diagnostic diagnostic delays three 79 [Interquartile range (IQR): 44-126] 27 (IQR: 13-73) days. One individual diagnosed with oral cancer, delay Facilitators identified encouragement by family low-cost at Major neglect their responsibilities towards family. Interpretation conclusions Although very few have CBAC, substantial them diagnosis. Screen treatment-seeking behaviour better undergoing centres. Measures need be taken improve literacy reduce

Language: Английский

The Impact of Oral Microbiome Dysbiosis on the Aetiology, Pathogenesis, and Development of Oral Cancer DOI Open Access
Jasminka Talapko,

Suzana Erić,

Tomislav Meštrović

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(17), P. 2997 - 2997

Published: Aug. 28, 2024

Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer. Although oral cavity an easily accessible area for visual examination, OSCC more often detected at advanced stage. The global prevalence of around 6%, with increasing trends posing a significant health problem due to increase in morbidity mortality. microbiome has been target numerous studies, findings highlighting role dysbiosis developing OSCC. Dysbiosis can significantly pathobionts (bacteria, viruses, fungi, parasites) that trigger inflammation through their virulence pathogenicity factors. In contrast, chronic bacterial contributes development Pathobionts also have other effects, such as impact on immune system, which alter responses contribute pro-inflammatory environment. Poor hygiene carbohydrate-rich foods risk factors mechanisms are not yet fully understood remain frequent research topic. For this reason, narrative review concentrates issue potential cause OSCC, well underlying involved.

Language: Английский

Citations

6
Beyond Genetics: Exploring Lifestyle, Microbiome, and Social Determinants in Oral Cancer Development DOI Open Access
Anil G. Menon, Vimi Sunil Mutalik, Yongqiang Chen

et al.

Cancers, Journal Year: 2025, Volume and Issue: 17(7), P. 1094 - 1094

Published: March 25, 2025

Oral cancer refers to cancers originating in the oral cavity and oropharyngeal regions. It is 16th most prevalent sixth leading cause of cancer-related deaths. However, mechanisms its progression are still being understood, interventions provide early diagnosis need be improved. More studies have recently been conducted on cancer, many reviews summarized findings this field, focusing individual factors. few review articles evaluated combinational impacts different factors cancer. This aimed an overview effects three extracellular factors, including lifestyle habits, microbiome, socioeconomic progression. differentially affected by habits; high-sugar diets, processed foods, alcohol, smoking, possibly sleep disorders benefit progression, whereas eating natural such as fruits, vegetables, fish, garlic, drinking tea or coffee, physical exercise can combat it. The microbiome could suppress promote Low status impact development. Furthermore, crosstalk among these affects has limitations not all cancer-affecting important publications. focus should placed multiple treatment. study update researchers landscape help formulate approaches prevention

Language: Английский

Citations

0
Artificial intelligence-driven clinical decision support systems for early detection and precision therapy in oral cancer: a mini review DOI Creative Commons

Manoj Kumar Karuppan Perumal,

Remya Rajan Renuka,

Suresh Kumar

et al.

Frontiers in Oral Health, Journal Year: 2025, Volume and Issue: 6

Published: April 28, 2025

Oral cancer (OC) is a significant global health burden, with life-saving improvements in survival and outcomes being dependent on early diagnosis precise treatment planning. However, planning are predicated the synthesis of complicated information derived from clinical assessment, imaging, histopathology patient histories. Artificial intelligence-based decision support systems (AI-CDSS) provides viable solution that can be implemented via advanced methodologies for data analysis, better diagnostic prognostic evaluation. This review presents AI-CDSS as promising through comprehensive analysis. In addition, it examines current implementations facilitate OC detection, staging, personalized by processing multimodal machine learning, computer vision, natural language processing. These effectively interpret results, identify critical disease patterns (including stage, site, tumor dimensions, histopathologic grading, molecular profiles), construct profiles. approach allows reduction delays improved intervention outcomes. Moreover, also optimizes plans basis unique parameters, stages risk factors, providing therapy.

Language: Английский

Citations

0
Characterization of Volatile Compounds and Evaluation of Antibacterial, Antifungal, and Cytotoxic Properties of Stachys palaestina from Palestine DOI
Nidal Jaradat, Mohammed Hawash, Nawaf Al‐Maharik

et al.

Arabian Journal for Science and Engineering, Journal Year: 2024, Volume and Issue: unknown

Published: July 19, 2024

Language: Английский

Citations

1
Agreement between patient-reported and clinician-rated speech and swallowing outcomes – Understanding the trend in post-operative oral cavity cancer patients DOI Creative Commons

Hasmithaa Balaji,

Venkataraja U. Aithal,

Janet Jaison Varghese

et al.

Oral Oncology, Journal Year: 2024, Volume and Issue: 159, P. 107068 - 107068

Published: Oct. 14, 2024

Language: Английский

Citations

1
Oral Cancer Management is not just Treatment! But also, how early Pre-cancerous Lesions are Diagnosed & Treated!! DOI Open Access

Suresh Kishanrao

Archives of Cancer Science and Therapy, Journal Year: 2024, Volume and Issue: 8(1), P. 007 - 012

Published: April 12, 2024

Oral Cancer (OC) or squamous cell carcinoma of the oral cavity accounts for approximately 3% all cancers worldwide, with increased incidence in developing countries. The use tobacco is directly associated 80% cancers, especially older men over 40 years age. As nearly one-third Indian population 15 consume smokeless one other forms, a recent increase has been observed OC among women and young adults. Lately, sexual behaviors & homosexuals have resulted emergence oropharyngeal due to infection HPV 16. About 60% cancer cases India five-year survival rate, this can be improved 70% 90% by mere early detection stages I II various treatment modalities. Despite well-known benefits screening whole countries remains controversial. It imperative address cultural barriers societal norms, which limit acceptability participation programs many This unique challenge increasing morbidity requires horizontal integration health systems new services focused on control, gives best chance long-term survival, outcomes, affordable care! article based author’s experience overseeing 1 case 2 delayed diagnosis, outcomes relevant literature review, current guidelines management OC.

Language: Английский

Citations

0
Antitumor effects of ophiopogonin D on oral squamous cell carcinoma DOI

Nguyen Thi Kieu Trang,

Vu Phuong Dong,

Hoon Yoo

et al.

International Journal of Oral Biology, Journal Year: 2024, Volume and Issue: 49(2), P. 42 - 47

Published: June 30, 2024

Language: Английский

Citations

0
Cutaneous Metastasis of Oral Carcinoma Tongue: A Rare Case DOI Open Access

U Padmavathy,

Ambedkar Yadala,

Bhawana Ashok Badhe

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: July 18, 2024

Cutaneous metastasis from head and neck cancers is rare, typically presenting as single or multiple nodules. This report presents a truly unique intriguing case of squamous carcinoma the tongue, in which patient developed numerous metastatic nodules face neck, phenomenon rarely seen clinical practice. The patient, known was treated radically with concurrent chemoradiation. He presented small cutaneous lesions his upper chest, were confirmed malignancies. Despite receiving one cycle palliative chemotherapy, management this posed significant complex challenges, requiring deep understanding nature spread pathway for choosing appropriate management.

Language: Английский

Citations

0
Impact of a Health Promotion Program on Knowledge, Physical Health, Mental Health, and Social Health Behaviors in Individuals at Risk for Colorectal Cancer DOI Creative Commons

Surachet Fakkiew,

Supat Teravecharoenchai,

Panit Khemtong

et al.

Societies, Journal Year: 2024, Volume and Issue: 14(9), P. 182 - 182

Published: Sept. 13, 2024

Colorectal cancer (CRC) is a significant public health issue, particularly in low- and middle-income countries like Thailand. While numerous studies advocate for regular screenings promotion programs to mitigate CRC risk, there notable lack of tailored models specifically designed high-risk groups This research aims develop model prevent through quasi-experimental design. The study involved 68 Thai participants aged 40–70 years, divided equally into experimental comparison groups. Independent-Samples t-test, Paired-Samples one-way variance test (F-test) were employed analyze the data. baseline average scores physical health, mental social knowledge on health-promoting behaviors between revealed no differences. However, following experiment, (t = −2.81, p 0.01) −10.30, < 0.001) significantly higher compared pre-experiment levels, with exception 0.07, 0.94). Furthermore, related promoting physical, mental, group also showed increase after experiment −4.53, 0.001). findings suggest that personnel should annual screening implementation programs, especially focusing aspects at-risk populations. underscores need long-term achieve continuous sustainable improvements these

Language: Английский

Citations

0
A Cross-Sectional Study on Oral Potentially Malignant Disorders: Diagnostic Challenges in Early Detection of Dysplasia and the Role of Velscope DOI Open Access
Mounika Yeladandi,

Umamaheswari Thirupambaram Nataraja Sundaram,

Dhanya Muthukumaran

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 16, 2024

The oral cancer burden has become a global challenge in the present scenario. Early diagnosis of potentially malignant disorders (OPMDs) with dysplasia is crucial to increasing overall survival rate patients. Efficient chairside techniques are much needed enhance diagnostic efficacy at early stages. This study evaluates effectiveness Velscope detecting dysplastic lesions and analyzes impact lifestyle factors on prevalence progression among 40 participants.

Language: Английский

Citations

0