International Journal of Scientific Reports,
Journal Year:
2023,
Volume and Issue:
9(12), P. 406 - 408
Published: Nov. 9, 2023
In
diabetes
mellitus
(DM)
patients
with
peripheral
neuropathy,
the
diabetic
foot
infection
(DFI)
often
begins
a
small
wound
that
may
not
easily
detect
and
then
progresses
to
more
complex
wound.
Diabetic
ulcer
(DFU)
is
estimated
occur
in
approximately
25%
of
individuals
India.
The
bacterial
one
important
cause
for
chronicity
DFU
are
accountable
high
medical
costs
as
well
affecting
patients’
quality
life
significantly.
Preventing
secondary
infections
an
function
dressing.
There
many
dressings
available
DFU,
choosing
right
dressing
parameter
management
ultimately
preventing
limb
amputation.
this
case,
patient
presented
non-healing
infected
we
used
Theruptor
Novo
management.
was
efficient
exudate
which
helped
accelerated
healing.
Indian Journal of Physical Medicine and Rehabilitation,
Journal Year:
2024,
Volume and Issue:
34(3), P. 212 - 217
Published: Sept. 1, 2024
Abstract
Introduction:
Effective
wound
care
is
crucial
in
managing
diabetic
foot
ulcers
(DFU),
with
practices
such
as
cleaning
and
maintaining
moisture
being
essential.
The
total-contact
cast
(TCC)
a
recognized
effective
method
for
off-loading
plantar
ulcers.
This
study
compares
the
effectiveness
of
platelet-rich
plasma
(PRP)
normal
saline
(NS)
dressings,
both
combined
TCC,
treatment
DFUs.
Methods:
A
total
108
patients
were
randomly
divided
into
three
groups:
PRP,
NS,
36
each
group.
PRP
group
received
autologous
followed
by
TCC
application,
NS
wet
dressings
had
alone.
Patients
every
15
days
90
days,
measurements
taken
reapplied
at
visit.
Wound
healing
was
assessed
based
on
time
to
heal
PUSH
score.
Results:
Baseline
sizes
similar
across
groups,
but
day
90,
showed
greater
reduction
size
(0.61±1.20)
compared
(1.58±1.55)
groups
(1.22±1.34).
also
most
significant
improvement
scores,
indicating
superior
healing.
Conclusion:
are
all
DFU
treatment,
statistically
enhancing
reducing
frequency
hospital
Edelweiss Applied Science and Technology,
Journal Year:
2024,
Volume and Issue:
8(6)
Published: Dec. 17, 2024
Fibrinolytic
proteases
play
an
important
role
in
the
fibrin
degradation
process,
which
is
crucial
treatment
of
chronic
wounds
as
a
debridement
agent.
Fibrinolytics
work
by
breaking
down
tissue
that
forms
part
blood
clot
leading
to
cell
necrosis.
Metabacillus
sp.
CS-2
known
be
one
potential
sources
fibrinolytic
protease
production
with
high
activity.
This
study
aims
examine
activity
and
specificity
produced
before
after
ultrafiltration
process
zymography.
In
this
study,
crude
extraction
was
carried
out
from
followed
improve
purity
enzyme.
The
obtained
ultra-filtrate
then
characterized
for
its
4
protein
substrates,
i.e.
casein,
gelatine,
fibrin,
collagen.
results
showed
enzyme
improved
0.342
0.011
0.768
0.014
U/mL
min-1.
zymogram
confirmed
can
degrade
all
substrates
tested.
Interestingly,
most
specific
substrate
evidenced
intense
clear
zone
smeared
low
sizes.
conclusion,
proven
effective
increasing
proteases.
ability
collagen
likely
supports
strain
function
agent
wound
healing
treatment.
International Journal of Scientific Reports,
Journal Year:
2023,
Volume and Issue:
9(12), P. 406 - 408
Published: Nov. 9, 2023
In
diabetes
mellitus
(DM)
patients
with
peripheral
neuropathy,
the
diabetic
foot
infection
(DFI)
often
begins
a
small
wound
that
may
not
easily
detect
and
then
progresses
to
more
complex
wound.
Diabetic
ulcer
(DFU)
is
estimated
occur
in
approximately
25%
of
individuals
India.
The
bacterial
one
important
cause
for
chronicity
DFU
are
accountable
high
medical
costs
as
well
affecting
patients’
quality
life
significantly.
Preventing
secondary
infections
an
function
dressing.
There
many
dressings
available
DFU,
choosing
right
dressing
parameter
management
ultimately
preventing
limb
amputation.
this
case,
patient
presented
non-healing
infected
we
used
Theruptor
Novo
management.
was
efficient
exudate
which
helped
accelerated
healing.
