Prevalence and Prognostic Impact of Diabetes Mellitus in Hospitalized COVID-19 Patients: A Monocentric Study From India DOI Open Access
Nidhi Tripathy,

Ashutosh Kumar Jain,

Jaya Jain

et al.

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 4, 2025

Background COVID-19 has been a fatal pandemic in modern history, with diabetes mellitus (DM) as common comorbidity. However, data on the effect of DM Indian patients are still scarce. We aimed to evaluate prevalence and prognostic impact hospitalized at Index Medical College Hospital Research Center (IMCHRC), Indore, Madhya Pradesh. Methods This is retrospective monocentric observational study including all consecutive adult admitted our center from July 2021 March 2022. Data demographics, clinical features, laboratory investigations, comorbidities, disease severity, intensive care unit (ICU) admission, invasive fungal infections, multi-organ dysfunction, death were retrieved medical records analyzed. Results A total 357 (236 males) mean age 52+9.7 years evaluated. The overall was 32% (115/357), comprising 23% (83/357) cases pre-existing 9% (32/357) new onset DM. Vascular comorbidities consisting hypertension (62% vs 27%; p=0.002), cardiovascular (39% 21%; p=0.016), kidney (42% p=0.019) significantly associated Diabetic versus non-diabetic had higher rate ICU admission (23% 10%; p=0.042), severe (43% [49/115] 5% [13/242]; acute respiratory distress syndrome (25% 7%), secondary infections (30% 11%; p=0.033), dysfunction (16% 9%; p=0.045), in-hospital mortality (21% [24/115] 6% [15/242]; p=0.011). Conclusions Our shows high an adverse prognosis increased severity mortality.

Language: Английский

Prevalence and Prognostic Impact of Diabetes Mellitus in Hospitalized COVID-19 Patients: A Monocentric Study From India DOI Open Access
Nidhi Tripathy,

Ashutosh Kumar Jain,

Jaya Jain

et al.

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 4, 2025

Background COVID-19 has been a fatal pandemic in modern history, with diabetes mellitus (DM) as common comorbidity. However, data on the effect of DM Indian patients are still scarce. We aimed to evaluate prevalence and prognostic impact hospitalized at Index Medical College Hospital Research Center (IMCHRC), Indore, Madhya Pradesh. Methods This is retrospective monocentric observational study including all consecutive adult admitted our center from July 2021 March 2022. Data demographics, clinical features, laboratory investigations, comorbidities, disease severity, intensive care unit (ICU) admission, invasive fungal infections, multi-organ dysfunction, death were retrieved medical records analyzed. Results A total 357 (236 males) mean age 52+9.7 years evaluated. The overall was 32% (115/357), comprising 23% (83/357) cases pre-existing 9% (32/357) new onset DM. Vascular comorbidities consisting hypertension (62% vs 27%; p=0.002), cardiovascular (39% 21%; p=0.016), kidney (42% p=0.019) significantly associated Diabetic versus non-diabetic had higher rate ICU admission (23% 10%; p=0.042), severe (43% [49/115] 5% [13/242]; acute respiratory distress syndrome (25% 7%), secondary infections (30% 11%; p=0.033), dysfunction (16% 9%; p=0.045), in-hospital mortality (21% [24/115] 6% [15/242]; p=0.011). Conclusions Our shows high an adverse prognosis increased severity mortality.

Language: Английский

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