Rubia akane Nakai Fruit Extract Improves Obesity and Insulin Sensitivity in 3T3-L1 Adipocytes and High-Fat Diet-Induced Obese Mice
Juhye Park,
No information about this author
Eunbi Lee,
No information about this author
Ju‐Ock Nam
No information about this author
et al.
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(5), P. 1833 - 1833
Published: Feb. 20, 2025
A
rise
in
obesity
during
the
COVID-19
pandemic
has
spurred
development
of
safe
and
effective
natural
anti-obesity
agents.
In
this
study,
we
propose
Rubia
akane
Nakai
fruit
extract
(RFE)
as
a
potential
product-based
agent.
R.
is
plant
Rubiaceae
family
that
grows
throughout
Republic
Korea.
Its
roots
have
long
been
used
medicinally
are
known
for
various
bioactivities,
but
fruit’s
bioactivities
unexplored.
We
investigated
effects
RFE
using
3T3-L1
adipocytes
high-fat
diet-induced
obese
mice.
adipocytes,
inhibited
adipogenic
differentiation
lipogenesis
by
downregulating
PPARγ
(peroxisome
proliferator-activated
receptor
γ),
C/EBPα
(CCAAT
enhancer-binding
protein
α),
SREBP-1
(sterol
regulatory
element-binding
1)
through
AMPK
(AMP-activated
kinase)
activation
delaying
initiation
MCE
(mitotic
clonal
expansion),
which
essential
early
adipogenesis.
At
vivo
level,
improved
phenotypes
insulin
resistance.
white
adipose
tissue,
not
only
suppressed
also
sensitivity
upregulating
basal
GLUT4
(glucose
transporter
type
4)
expression.
Therefore,
study
advances
treatment
Language: Английский
Angelica gigas Nakai extract exerts anti-obesity effects by inducing lipolysis and thermogenesis in 3T3-L1 adipocytes
Juhye Park,
No information about this author
Eunbi Lee,
No information about this author
Ju‐Ock Nam
No information about this author
et al.
Journal of Applied Biological Chemistry,
Journal Year:
2025,
Volume and Issue:
68
Published: April 28, 2025
Language: Английский
Correlation Analysis among Searches of Anti-Obesity Medications, Herbal Medicine, and Supplements Using Big Data: from 2016 to 2024
Journal of Korean Medicine for Obesity Research,
Journal Year:
2024,
Volume and Issue:
24(2), P. 133 - 143
Published: Dec. 31, 2024
대한비만학회에서
발표한
2023년
obesity
fact
sheet에
의하면
서구화된
식습관
등에
의해
최근
10년간
성인의
비만
유병률은
지속적으로
A systematic review and keyword network analysis of Korea Citation Index Journals (2004–2023)
Eun-Sil Her,
No information about this author
Erk Her
No information about this author
Korean Journal of Community Nutrition,
Journal Year:
2024,
Volume and Issue:
29(6), P. 445 - 454
Published: Dec. 31, 2024
Objectives:
Obesity
rates
are
rapidly
rising
in
Korea.
Weight
control
is
highly
involved
obesity
treatment.
This
study
aimed
to
explore
research
trends
related
weight
through
keyword
network
analysis.
By
focusing
on
journals
indexed
the
Korea
Citation
Index
(KCI),
this
highlights
specific
Korea,
offering
insights
that
reflect
country’s
unique
cultural
and
policy
contexts
research.Methods:
collected
keywords
from
control-related
papers
published
KCI
journal
over
past
20
years.
Keywords
were
cleaned
Textom
(2024),
relationships
between
key
issue
frequency
analysis,
structural
characteristics,
identified
using
Textom,
UCINET6,
NetDraw.Results:
Over
years,
40
50
studies
have
been
conducted
each
year.
The
Korean
Journal
of
Community
Nutrition
had
largest
number
articles.
Keyword
analysis
showed
‘obesity’
highest
frequency.
And
degree
centrality
betweenness
centrality,
ranked
highest.
CONCOR
four
clusters:
preventive
health
care,
management,
physical
health,
personal
development.Conclusion:
results
reflecting
characteristics
times
has
steadily
progressing
relation
increasing
when
developing
policies
or
setting
directions
loss
future,
should
be
a
prospective
manner
by
subdividing
it
according
groups
interests.
Language: Английский