A pathway study of factors influencing anxiety in patients with gestational diabetes mellitus

BMC Pregnancy and Childbirth, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 24, 2025

This study aims to assess anxiety severity among patients with and elucidate the predominant psychological factors, informing development of targeted management strategies. The cross-sectional recruited 421 GDM via convenience sampling from Guangdong Province, China. Self-administered questionnaires, including Pregnancy-related Anxiety Scale, Simplified Coping Style Questionnaire, Type D Personality Perceived Social Support General Self-Efficacy were utilized gather data. Data analysis was performed using Structural Equation Modeling (SEM) in AMOS 25.0 SPSS 25.0. Among GDM, significantly positively associated negative coping styles (β = 0.190, P < 0.01) personality 0.167, 0.01), indicating their roles exacerbating anxiety. In contrast, positive (β=-0.136, perceived social support (β=-0.206, general self efficacy (β=-0.49, had direct impacts on anxiety, suggesting protective influence. Mediation revealed that exerted significant mediating effects pathway through explaining 16% indirect effect 2.302, 95% CI: 1.411 ~ 3.350) 32% 4.528, 3.231 5.913). identifies key modifiers could mitigate improve pregnancy outcomes.

Language: Английский

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Impact of maternal COVID-19 infection on offspring immunity and maternal-fetal outcomes at different pregnancy stages: a cohort study

BMC Pregnancy and Childbirth, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 28, 2025

To investigate the impact of COVID-19 infection on maternal and neonatal outcomes immunity in pregnant women China. 283 with were included prospective observational cohort study divided into five groups based stage. Antibody levels measured plasma, umbilical cord blood, breast milk, combined clinical data 6-month follow-up results. We SARS-CoV-2 antibody using a chemiluminescence immunoassay analyzed Kruskal-Wallis test, χ2 or Fisher's exact test. No significant differences found age, BMI, weight change during pregnancy, incidence gestational hypertension, diabetes, hypothyroidism, intrahepatic cholestasis, transaminitis, preterm birth, small for NICU transfers, developmental delays, hearing damage among groups. The infants from mothers infected at different stages pregnancy was significantly lower than uninfected group (P < 0.05). Maternal blood showed higher IgG compared to median transplacental transfer ratio across all 1.15 (0.98–1.30), no between them. reinfection had IgA other adverse observed any stage infection. Antibodies milk may offer passive newborns 1–3 months. Reinfection extend this without raising risk outcomes.

Language: Английский

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Increasing Preterm Delivery and Small for Gestational Age Trends in South Carolina during the COVID-19 Pandemic

International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 21(4), P. 465 - 465

Published: April 10, 2024

Preterm delivery (PTD) complications are a major cause of childhood morbidity and mortality. We aimed to assess trends in PTD small for gestational age (SGA) whether varied between race–ethnic groups South Carolina (SC). utilized 2015–2021 SC vital records linked hospitalization emergency department records. was defined as clinically estimated gestation less than (<) 37 weeks (wks.) with subgroup analyses < 34 wks. 28 SGA infants weighing below the 10th percentile age. This retrospective study included 338,532 (243,010 before COVID-19 pandemic 95,522 during pandemic) live singleton births ≥ 20 born 260,276 mothers SC. Generalized estimating equations change-point first quarter 2020 helped trends. In unadjusted analyses, pre-pandemic showed an increasing trend that continued (relative risk (RR) = 1.04, 95% CI: 1.02–1.06). rose (RR 1.07, 1.02–1.12) significant change slope. Trends by race ethnicity, only Hispanics 1.02, 1.00–1.04) pandemic. Our reveals prevalence rise pandemic, well period.

Language: Английский

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Potential Protective Effect of Anti-zinc Transporter 8 Autoantibodies on Gestational Diabetes Mellitus in Iraqi Population

Biomedical and Biotechnology Research Journal (BBRJ), Journal Year: 2024, Volume and Issue: 8(1), P. 100 - 107

Published: Jan. 1, 2024

Background: The human zinc transporter 8 (ZNT8), also known as the solute carrier family 30A, member (SLC30A8), is a β-cell specific integral membrane protein, mainly restricted to of insulin secretory granules. ZnT8 plays crucial role in both synthesis and secretion well viability β-cells. recently identified autoantibodies targeting surface epitopes have been proposed new risk factor for gestational diabetes mellitus (GDM). Due lack prior research studies on against immunologic etiology GDM Iraqi population, this study has designed explore association between rs13266634 C>T polymorphism SLC30A8 gene serum levels Zinc Transporter-8 Autoantibody (ZnT8A) women diagnosed with GDM. Methods: A total 50 participants controls from Baghdad Teaching Hospital/Pregnancy Care unit at Medical City, Baghdad, Iraq, were recruited case–control study. Serum ZnT8A assayed enzyme-linked immunosorbent assay, Taqman real time polymerase chain reaction (RT-PCR) was used single nucleotide (SNP) genotyping. Results: significantly lower than non-GDM ( P ≤ 0.01). level 20.0 pg/mL associated threefold higher 0.001. subjects 0.05). T allele SNP conferred = 0.002). In view that, TT genotype, compared CC showed significant increased concentrations low among who had CT genotype 0.003). Conclusion: variant appears play key determining autoimmunity by inducing an autoantibody response due its hyperactivity transportation.

Language: Английский

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Impact of COVID-19 on pregnancy and fetal outcomes in women with multiple sclerosis

Multiple Sclerosis Journal, Journal Year: 2024, Volume and Issue: 30(6), P. 707 - 713

Published: March 8, 2024

In the general population, maternal COVID-19 is associated with worse and fetal outcomes. Two previous studies have assessed clinical outcomes in pregnant women multiple sclerosis (MS), but there are no data about

Language: Английский

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The Impact of Telemedicine during the COVID-19 Pandemic on Diabetes Management and Pregnancy Outcomes in Women with Gestational Diabetes Mellitus (GDM)

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(19), P. 5797 - 5797

Published: Sept. 28, 2024

Background/Objectives: Gestational diabetes mellitus (GDM) can lead to various complications for both the mother and child. Many factors influence onset of disease including GDM in a previous pregnancy, overweight obesity, as well increasing age women who become pregnant. The aim this study was assess impact telemedicine during COVID-19 pandemic on management pregnancy outcomes with gestational (GDM). Methods: A retrospective analysis conducted. We compared two groups from pre-pandemic periods terms course obstetric outcomes. Results: It observed that group were significantly more often less obese before than group. diagnosed earlier but later pregnancies similar percentage delivery neonates > 4000 g did not differ significantly. number caesarean sections spontaneous deliveries also periods. No differences found anthropometric parameters newborns neonatal maternal complications. Conclusions: occurrence necessity employing tools medical care achieved.

Language: Английский

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The COVID-19 pandemic and its impact on the development of gestational diabetes mellitus (GDM) in West Virginia

Diabetes Research and Clinical Practice, Journal Year: 2024, Volume and Issue: 208, P. 111126 - 111126

Published: Feb. 1, 2024

Language: Английский

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Association between chronic health conditions and severe acute respiratory syndrome in pregnant women: an exploratory study

Revista da Escola de Enfermagem da USP, Journal Year: 2024, Volume and Issue: 58

Published: Jan. 1, 2024

ABSTRACT Objective: To analyze the association between chronic health conditions and severe acute respiratory syndrome in pregnant women. Method: Retrospective, exploratory study conducted with 1,152 women from all 27 states of Brazil who sought hospital treatment were diagnosed 2020 2022. Public data Influenza Epidemiological Surveillance Information System (SIVEP-Gripe) Brazilian Ministry Health used. Nonparametric tests performed interpretation. Results: The mortality rate due to was 7%. Severe statistically associated previous presence diabetes (p = 0.023), neurological disease 0.001), drug use 0.001). epidemiological investigation cases took longer Black 0.012), unvaccinated < 0.001) living north south country 0.011). Conclusion: more common diabetes, users. However, these did not lead an increase number deaths.

Language: Английский

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Associação entre condições crônicas de saúde e a síndrome respiratória aguda grave em gestantes: estudo exploratório

Revista da Escola de Enfermagem da USP, Journal Year: 2024, Volume and Issue: 58

Published: Jan. 1, 2024

RESUMO Objetivo: Analisar a associação entre condições crônicas de saúde e síndrome respiratória aguda grave em gestantes. Método: Estudo retrospectivo, exploratório realizado com 1.152 gestantes todos os 27 estados do Brasil que procuraram tratamento hospitalar foram diagnosticadas 2020 2022. Foram utilizados dados públicos Sistema Informação Vigilância Epidemiológica da Gripe (SIVEP-Gripe) Ministério Saúde Brasil. Realizamos testes não paramétricos para interpretação dos dados. Resultados: A taxa mortalidade por no foi 7%. estava estatisticamente associada à presença prévia diabetes (p = 0,023), doença neurológica 0,001) uso drogas 0,001). investigação epidemiológica casos demorou mais tempo negras 0,012), vacinadas < residentes na região norte sul país 0,011). Conclusão: comum diabetes, faziam drogas. Todavia, essas levaram ao aumento número mortes.

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