Examination of iatrogenic FDG accumulation after COVID-19 vaccination

Annals of Nuclear Medicine, Journal Year: 2024, Volume and Issue: 38(6), P. 409 - 417

Published: April 2, 2024

Language: Английский

Hypermetabolic Axillary Lymph Nodes Associated with COVID-19 Vaccination in Breast Cancer Management

Molecular Imaging and Radionuclide Therapy, Journal Year: 2023, Volume and Issue: 32(2), P. 181 - 185

Published: June 1, 2023

A 42-year-old female patient diagnosed with invasive ductal breast ca underwent 18F-fluorodeoxyglucose (FDG) positron emission tomography/ computed tomography (PET/CT) scan for staging, 1.5 cm diameter hypermetabolic lesion was observed in the lower inner quadrant of right that compatible primary tumor [maximum standardized uptake value (SUVmax): 10.5]. No pathological 18F-FDG lymph nodes whose fatty hilum seen axilla. However, left axilla and deep axilla, a maksimum 19 mm were (SUVmax: 8.0). In detailed CT evaluation, these have thicker walls than ones The questioned again coronavirus disease-2019 (COVID-19) vaccination history (with BNT162b2, COVID-19 mRNA vaccine) determined administrated to arm 5 days ago. Tru-cut biopsy performed from aksillary proved be reactive lymphoid tissue there no or metastatic axillary node tissues. given neoadjuvant chemotherapy 4.5 months after first PET/CT, second treatment response evaluation. Significant regression findings. total mastechtomy. She being followed up adjuvant radiotherapy. conclusion, axillas should interrogated patients cancer. Hypermetabolic on same side vaccinated PET/CT may related vaccine-induced enlargement. Lymph metastasis excluded, especially if are preserved contralateral as arm. Active vaccine become inactive while.Kırk iki yaşında, invaziv duktal meme kanseri tanısı alan, evreleme için 18F-florodeoksiglukoz pozitron emisyon tomografi/bilgisayarlı tomografi (PET/BT) taraması yapılan kadın hastada, sağ alt iç kadranda primer tümörle uyumlu 1,5 çaplı hipermetabolik lezyon izlendi [maksimum standartlaştırılmış alım değeri (SUVmaks): 10,5]. Sağ aksillada yağlı hilusu görülen lenf nodlarında patolojik tutulumu izlenmedi. Ancak sol aksilla ve derin gözlenen nodları mevcuttu (SUVmaks: 8,0). Ayrıntılı BT değerlendirmesinde, bu bezlerinin duvarları aksilladakilerden daha kalındı. Hasta tekrar sorgulandı gün önce koluna uygulanan koronavirüs hastalığı-2019 aşısı öyküsü (BNT162b2, ile) belirlendi. Sol aksiller nodlarından tru-cut biyopsi sonucu reaktif lenfoid doku olarak geldi veya metastatik tümör izlenmediği rapor edildi. Hastaya neoadjuvan kemoterapi verildi. İlk PET/BT’den 4,5 ay sonra, tedaviye yanıt değerlendirmesi ikincisi yapıldı. Bulgularda belirgin regresyon gözlendi. mastektomi radyoterapi ile takip ediliyor. Sonuç olarak, pandemi günlerinde kanserli hastalarda açısından sorgulanmalıdır. PET/BT taramasında aşılı kolun aynı tarafında nodları, aşıya bağlı lenfadenomegali ilişkili olabilir. Özellikle memedeki kitleye göre kontralateral ancak aşı kol taraftaki korunmuş değerlendirilerek nodu metastazı dışlanabilir. Olguda (aktif) nodlarının zamanla inaktif hale dönüşmesi gözlenmektedir.

Examination of iatrogenic FDG accumulation after COVID-19 vaccination

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 29, 2023

Abstract Purpose This study aimed to investigate the frequency of COVID-19 vaccine-induced reactive change and potential factors correlated with increased FDG uptake on positron emission tomography (PET)/computed (CT). Materials methods We evaluated 285 patients who underwent PET/CT between June September 2021 had a known history vaccination. Information injection site, vaccine type, adverse reactions was obtained. visually assessed presence or absence accumulation in axillary supraclavicular lymph nodes deltoid muscles. measured maximum standardized value (SUVmax) using semi-quantitative analysis. Results Our included 158 males 127 females aged 16 94 years. The median time vaccination nine 42 days for received their first second doses, respectively. observed node accumulation, muscle 99 (SUVmax 1.07–25.1), 2.28–14.5), 33 cases 0.93–7.42), In (P = 0.0066) 0.047) shorter since vaccination, higher accumulation. Patients were significantly younger < 0.0001) such as fever myalgia 0.001). Logistic regression analysis also showed that age, sex, important Conclusion found within after young patients, females, those myalgia. Confirming status, before PET may reduce false positives.

Language: Английский