Assessment of the Anti-Acne Properties of Some Medicinal Plants and Development of an Herbal Anti-Acne Formulation DOI Creative Commons
Fatma Sezer Şenol, Özlem Oyardı, Çagla Bozkurt-Güzel

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 317 - 317

Published: March 1, 2025

Background: Acne is a prevalent dermatological condition characterized by the blockage of hair follicles and sebaceous glands, leading to formation acne. The anaerobe pathogen Cutibacterium acnes (formerly known as Propionibacterium acnes) plays an essential role in pathogenesis acne, for which generally antimicrobial treatment required. substantial health concern, continuing research being conducted discover novel efficacious remedies. activity plants has been demonstrated numerous studies, they are still targeted organisms drug development. Studies showing that effective against acne pathogens have also reported. Methods: hydroethanolic extracts prepared from 30 plant species was determined C. standard strains (C. Scholz Kilian ATCC 11827 11828) clinical isolates our preliminary screening. Since inflammatory skin disease, anti-inflammatory effect six active through vitro inhibition collagenase, lipoxygenase (LOX), hyaluronidase xanthine oxidase (XO) enzymes. Results: Cotinus coggygria Scop. leaf extract displayed highest collagenase (79.75% 52.52%, respectively), while aerial parts Helichrysum arenarium (L.) Moench potent XO inhibitory (82.51%). Therefore, these two chosen further LC/MS-MS used determine phenolic profiles extracts. Conclusions: Subsequently, nanoemulgels were formulated with develop prototype herbal anti-acne product, characterization studies formulations conducted.

Language: Английский

Assessment of the Anti-Acne Properties of Some Medicinal Plants and Development of an Herbal Anti-Acne Formulation DOI Creative Commons
Fatma Sezer Şenol, Özlem Oyardı, Çagla Bozkurt-Güzel

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 317 - 317

Published: March 1, 2025

Background: Acne is a prevalent dermatological condition characterized by the blockage of hair follicles and sebaceous glands, leading to formation acne. The anaerobe pathogen Cutibacterium acnes (formerly known as Propionibacterium acnes) plays an essential role in pathogenesis acne, for which generally antimicrobial treatment required. substantial health concern, continuing research being conducted discover novel efficacious remedies. activity plants has been demonstrated numerous studies, they are still targeted organisms drug development. Studies showing that effective against acne pathogens have also reported. Methods: hydroethanolic extracts prepared from 30 plant species was determined C. standard strains (C. Scholz Kilian ATCC 11827 11828) clinical isolates our preliminary screening. Since inflammatory skin disease, anti-inflammatory effect six active through vitro inhibition collagenase, lipoxygenase (LOX), hyaluronidase xanthine oxidase (XO) enzymes. Results: Cotinus coggygria Scop. leaf extract displayed highest collagenase (79.75% 52.52%, respectively), while aerial parts Helichrysum arenarium (L.) Moench potent XO inhibitory (82.51%). Therefore, these two chosen further LC/MS-MS used determine phenolic profiles extracts. Conclusions: Subsequently, nanoemulgels were formulated with develop prototype herbal anti-acne product, characterization studies formulations conducted.

Language: Английский

Citations

0