Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2636 - 2636
Published: Dec. 19, 2024
Antibiotic
susceptibilities,
hemolytic
activities,
and
technological
properties
of
46
Leuconostoc
citreum
isolates
from
kimchi
were
evaluated
to
select
starter
candidates.
All
strains
susceptible
clindamycin
erythromycin,
while
some
exhibited
resistance
ampicillin,
chloramphenicol,
gentamicin,
streptomycin,
tetracycline;
all
resistant
kanamycin
based
on
the
EFSA
breakpoint
values
for
species.
PCR
analysis
did
not
detect
genes
these
six
antibiotics
in
any
strain.
None
demonstrated
clear
α-
or
β-hemolytic
activity.
thrived
a
medium
supplemented
with
6%
NaCl,
displaying
protease
activity
acid
media
containing
3%
respectively.
Consequently,
five
strains,
AK5T17,
AK5T19,
AK10M04,
DMLC16,
YK10T20,
identified
as
candidates,
L.
strain
DMLC16
emerging
top
choice
due
its
elevated
production
capacities.
These
findings
support
safe
application
candidate
fermented
food
production.
Annals of Microbiology,
Journal Year:
2024,
Volume and Issue:
74(1)
Published: Aug. 9, 2024
Abstract
Background
Antimicrobial
resistance
is
considered
one
of
the
greatest
threats
to
human
health,
according
World
Health
Organization
(WHO).
Gram-negative
bacteria,
especially
carbapenem-resistant
Enterobacteriaceae
(CRE),
have
become
a
significant
concern
in
antimicrobial-resistant
bacteria’s
global
emergence
and
spread.
Among
CRE
pathogens,
Klebsiella
pneumoniae
(CRKP)
has
recently
been
reported
as
highly
infectious
strain
associated
with
high
mortality
morbidity
adults
immunocompromised
patients.
Additionally,
CRKP-related
infections
are
challenging
treat,
carbapenems
last
resort
antibiotics.
Therefore,
developing
novel
drugs
different
mechanisms
action
from
existing
urgently
required
defeat
this
lethal
menace.
Under
such
circumstances,
probiotics
can
be
therapeutic
candidates
for
inhibiting
pathogens.
Thus,
our
research
team
focusing
on
long
time
develop
potential
anti-CRKP
drug
agents.
Methods
After
extensive
efforts,
we
finally
found
probiotic
strain,
Lactobacillus
sakei
PMC104,
suitable
treating
CRKP
infection.
It
was
isolated
kimchi.
As
part
expansion
into
development,
evaluated
L.
effect
against
pathogens
both
vitro
vivo
experiments.
Moreover,
conducted
media
optimization
at
food
grade
then
established
scale-up
process
pilot
scale.
Subsequently,
lyophilizate
obtained
used
mouse
model
infected
CRKP.
Results
Data
demonstrated
that
an
inhibitory
infection
experiments
also
increases
level
short-chain
fatty
acids
feces
mice
after
receiving
treatment
10
days.
Furthermore,
powder
remarkably
diminished
body
weight
loss,
mortality,
illness
severity
CRKP-infected
mice,
showing
preventive
PMC
104
Discussion
Our
results
demonstrate
candidate
CRKP,
suggesting
could
antimicrobial
infections.
However,
studies,
including
additional
toxicity
tests
clinical
trials,
still
essential
it
new
agent.
Nutrition Reviews,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 14, 2024
Abstract
Context
Increasing
global
kimchi
consumption
has
prompted
interest
in
its
health
impact.
However,
comprehensive
reviews
of
the
influence
on
cardiometabolic
risk
factors,
especially
meta-analyses,
remain
limited.
Objective
This
review
assessed
impact
fermented
factors
by
systematically
reviewing
human
intervention
and
prospective
cohort
studies,
conducting
a
meta-analysis
studies.
Data
Sources
A
literature
search
PubMed,
EMBASE,
Scopus,
Web
Science,
RISS,
KISS,
ScienceON
databases
was
conducted
through
April
30,
2024.
The
inclusion
criteria
encompassed
studies
that
examined
effects
kimchi,
without
any
added
ingredients
or
lactic
acid
bacteria,
outcomes,
including
anthropometric
measures,
blood
pressure,
glycemic
indicators,
inflammatory
cytokines,
incidence
related
chronic
diseases.
Extraction
extraction
quality
evaluation
were
independently
3
researchers.
Analysis
Pooled
effect
sizes
calculated
as
weighted
mean
differences
(WMDs)
with
95%
CIs
employing
random-effects
models.
Results
Five
(205
participants)
4
(42
455
selected.
revealed
significant
reduction
fasting
glucose
(WMD:
−1.93
mg/dL;
CI:
−3.82,
−0.03;
I2
=
17.4%)
following
kimchi.
After
excluding
contributed
to
increased
heterogeneity,
inverse
associations
observed
between
triglycerides
−28.9
−53.2,
−4.5;
0.0%),
systolic
pressure
−3.48
mmHg;
−5.95,
−1.01,
diastolic
−2.68
−4.75,
−0.62;
0.0%).
Prospective
linked
higher
intake
lower
cancer
metabolic
syndrome
an
likelihood
achieving
normal
body
weight.
Conclusion
supports
beneficial
health.
due
limited
number
these
findings
should
be
interpreted
cautiously,
highlighting
need
for
further
research
diverse
populations.
Systematic
Review
Registration
PROSPERO
registration
No.
CRD42024532020.
Foods,
Journal Year:
2024,
Volume and Issue:
13(18), P. 2872 - 2872
Published: Sept. 10, 2024
In
this
study,
we
investigated
the
effects
of
different
nitrite
sources
(sodium
or
white
kimchi
powder)
and
pink-generating
ligands
(cysteine,
histidine,
nicotinamide)
on
development
stability
cured
meat
color
in
pork
sausage
model
systems
over
30
d
refrigerated
storage.
The
samples
were
prepared
a
2
×
3
factorial
design
with
two
three
ligands,
their
physicochemical
properties
evaluated
days
0,
15,
30.
Although
powder
induced
similar
to
that
synthetic
sodium
nitrite,
it
resulted
higher
cooking
loss
lower
residual
content
sausages
(
Journal of Ethnic Foods,
Journal Year:
2024,
Volume and Issue:
11(1)
Published: Oct. 22, 2024
Abstract
Kimchi,
a
renowned
and
culturally
significant
Korean
dish,
has
gained
global
recognition
as
superfood
due
to
its
abundant
nutritional
content
positive
impact
on
human
health.
The
process
of
producing
kimchi
involves
the
fermentation
various
vegetables
using
lactic
acid
bacteria
(LAB).
primary
genera
LAB
encompass
Lactobacillus
,
Lactococcus
Leuconostoc
Pediococcus
Weissella
.
Impressively,
comes
in
over
200
varieties
with
cruciferous
main
ingredients,
complemented
by
range
secondary
ingredients
that
contribute
holistic
health
benefits.
These
include
salted
fish,
ginger,
garlic,
red
pepper
powder.
Due
functional
properties,
attracted
considerable
interest.
Kimchi
been
extensively
studied,
recognized
benefits,
including
anti-oxidant,
anti-tumor,
anti-inflammatory,
anti-microbial,
anti-obesity,
hepatoprotective,
neuroprotection,
anti-allergic,
regulation
immunological
responses,
many
more,
have
covered
review
papers.
A
current
literature
regarding
anti-obesity
properties
is
currently
lacking.
Therefore,
present
directed
attention
towards
concerning
derived
from
last
five
years.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2636 - 2636
Published: Dec. 19, 2024
Antibiotic
susceptibilities,
hemolytic
activities,
and
technological
properties
of
46
Leuconostoc
citreum
isolates
from
kimchi
were
evaluated
to
select
starter
candidates.
All
strains
susceptible
clindamycin
erythromycin,
while
some
exhibited
resistance
ampicillin,
chloramphenicol,
gentamicin,
streptomycin,
tetracycline;
all
resistant
kanamycin
based
on
the
EFSA
breakpoint
values
for
species.
PCR
analysis
did
not
detect
genes
these
six
antibiotics
in
any
strain.
None
demonstrated
clear
α-
or
β-hemolytic
activity.
thrived
a
medium
supplemented
with
6%
NaCl,
displaying
protease
activity
acid
media
containing
3%
respectively.
Consequently,
five
strains,
AK5T17,
AK5T19,
AK10M04,
DMLC16,
YK10T20,
identified
as
candidates,
L.
strain
DMLC16
emerging
top
choice
due
its
elevated
production
capacities.
These
findings
support
safe
application
candidate
fermented
food
production.
