Nutrients, Journal Year: 2024, Volume and Issue: 17(1), P. 42 - 42
Published: Dec. 27, 2024
Biomarkers constitute a valuable tool to diagnose both the incidence and prevalence of chronic diseases may help inform design effectiveness precision nutrition interventions. Cardiovascular disease (CVD) continues be foremost cause death all over world. While reasons that lead increased risk for CVD are multifactorial, dyslipidemias, plasma concentrations specific lipoproteins, dynamic measures lipoprotein function strong biomarkers predict document coronary heart incidence. The aim this review is provide comprehensive evaluation emerging approaches can utilized characterize profiles as predictive tools assessing risk, including assessment traditional clinical lipid panels, efflux capacity inflammatory antioxidant activity, omics-based characterization composition regulators metabolism. In addition, we discuss demographic, genetic, metagenomic, lifestyle determinants profiles—such age, sex, gene variants single-nucleotide polymorphisms, gut microbiome profiles, dietary patterns, physical inactivity, obesity status, smoking alcohol intake, stress—which likely essential factors explain interindividual responses recommendations mitigate risk.
Language: Английский