The Role of Neutrophil-to-Lymphocyte Ratio and Right Ventricular Dysfunction in Indonesian Patients with COVID-19: A Retrospective Cohort Study DOI Open Access
Raksheeth Agarwal, Stanislaus Ivanovich Krishnanda, Oliver Emmanuel Yausep

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(6), P. 2051 - 2051

Published: March 18, 2025

Background/Objectives: The clinical impact of neutrophil-to-lymphocyte ratio (NLR) and right ventricular (RV) dysfunction on outcomes in COVID-19 remains understudied the Indonesian population. This study aims to investigate their prognostic value hospitalized adults with COVID-19. Methods: A retrospective cohort was conducted at a referral hospital Indonesia. We included all consecutive between April 2020 2021 who underwent transthoracic echocardiography (TTE) during admission. Clinical information extracted from electronic medical records. TTE variables were defined according American Society Echocardiography criteria. Statistical analyses performed using SPSS. Ethical approval obtained Institutional Review Board Universitas Indonesia (#2022-01-135). Results: total 488 patients this study—29 459 without RV dysfunction. mean age population 54.8, 42% being female. An NLR >4.793 considered elevated. Elevated independently associated (OR: 3.38, p = 0.02). Older (HR: 1.02, 0.01), obesity 1.85, < chronic kidney disease 1.69, high 2.75, 0.001), 2.07, 0.02) increased risk 30-day mortality by multivariate Cox regression analysis. Conclusions: In adult COVID-19, an elevated dysfunction, both these parameters mortality. highlights importance patients, providing physicians tools identify high-risk patients.

Language: Английский

The Role of Neutrophil-to-Lymphocyte Ratio and Right Ventricular Dysfunction in Indonesian Patients with COVID-19: A Retrospective Cohort Study DOI Open Access
Raksheeth Agarwal, Stanislaus Ivanovich Krishnanda, Oliver Emmanuel Yausep

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(6), P. 2051 - 2051

Published: March 18, 2025

Background/Objectives: The clinical impact of neutrophil-to-lymphocyte ratio (NLR) and right ventricular (RV) dysfunction on outcomes in COVID-19 remains understudied the Indonesian population. This study aims to investigate their prognostic value hospitalized adults with COVID-19. Methods: A retrospective cohort was conducted at a referral hospital Indonesia. We included all consecutive between April 2020 2021 who underwent transthoracic echocardiography (TTE) during admission. Clinical information extracted from electronic medical records. TTE variables were defined according American Society Echocardiography criteria. Statistical analyses performed using SPSS. Ethical approval obtained Institutional Review Board Universitas Indonesia (#2022-01-135). Results: total 488 patients this study—29 459 without RV dysfunction. mean age population 54.8, 42% being female. An NLR >4.793 considered elevated. Elevated independently associated (OR: 3.38, p = 0.02). Older (HR: 1.02, 0.01), obesity 1.85, < chronic kidney disease 1.69, high 2.75, 0.001), 2.07, 0.02) increased risk 30-day mortality by multivariate Cox regression analysis. Conclusions: In adult COVID-19, an elevated dysfunction, both these parameters mortality. highlights importance patients, providing physicians tools identify high-risk patients.

Language: Английский

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