The Impact of Poor Sleep Quality on Cardiovascular Risk Factors and Quality of Life

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

This review article examines the impact of poor sleep quality on cardiovascular risk factors and life. Insufficient disturbances in have been linked to a variety negative health outcomes, including an increased disease, elevated blood pressure, obesity, reduced explores available evidence connecting with these conditions, analyzing underlying mechanisms pathways involved. Additionally, challenges posed by night work, which can contribute subsequent problems, are discussed. The also discusses evidence-based strategies for improving quality, encompassing hygiene practices, bright light therapy, cognitive behavioral therapy insomnia, pharmacological interventions, emerging digital solutions. aim is analyze current research emphasize crucial role prioritizing maintaining both

Language: Английский

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The mutual impacts of stem cells and sleep: opportunities for improved stem cell therapy

Stem Cell Research & Therapy, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 29, 2025

Abstract Sleep is an indispensable physiological function regulated by circadian rhythms, which influence the biological pathways and overall health of body. crucial for maintenance restoration bodily systems, disturbances can lead to various sleep disorders, impair both mental physical health. Treatment options these disorders encompass lifestyle modifications, psychotherapy, medications, therapies such as light therapy surgery. Not only deprivation has a significant impact on essential organs, but it also influences types stem cells in In this review, we explore connection between cells, highlighting how rhythms regulate cell activities that are vital tissue regeneration homeostasis. Disruptions hinder self-renewal, homing, proliferation, function, differentiation, thereby affecting We discuss transplantation their products may help improve quality affects behavior, implications therapies. Notably, while certain transplantations disrupt sleep, enhancing efficacy Finally, be utilized model offering valuable insights into underlying mechanisms.

Language: Английский

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Oral Cancer and Sleep Disturbances: A Narrative Review on Exploring the Bidirectional Relationship

Cancers, Journal Year: 2025, Volume and Issue: 17(8), P. 1262 - 1262

Published: April 8, 2025

Oral cancer is a common malignant tumor, and its incidence has steadily increased in recent years. Sleep disturbances, including insomnia obstructive sleep apnea, are prevalent among patients with oral significantly impact their quality of life. Emerging research suggests bidirectional relationship between disorders. This article reviews how induces or exacerbates disorders, particularly apnea (OSA), through factors such as pain, psychological stress, treatment-related side effects (e.g., upper airway damage caused by chemotherapy, radiotherapy, surgical interventions). Furthermore, it analyzes disorders may promote progression via chronic inflammation, intermittent hypoxia, oxidative disruption circadian rhythms. By elucidating these interactions, this review provides theoretical foundation for optimizing clinical treatment plans holistic understanding shared pathophysiological mechanisms.

Language: Английский

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Obesity and the Risk of Thyroid Cancer: A Literature Review

Quality in Sport, Journal Year: 2024, Volume and Issue: 19, P. 54187 - 54187

Published: Sept. 1, 2024

Introduction and aim of the study: Thyroid cancer is considered most common endocrine malignant worldwide in recent years. Also, obesity has become a true pandemic. The correlation between increase cases not only but also thyroid could be explained solely by earlier more meticulous diagnoses. This study aims to review literature on relationship risk cancer. Materials Methods: authors conducted comprehensive available PubMed Medline databases focusing terms "thyroid cancer" "obesity". Results: Obesity associated with state chronic inflammation nonspecific activation immune system, leading production cytokines adipokines. These elements, through complex mechanisms, directly indirectly promote carcinogenesis. Despite association excessive body weight tumor development, oncological treatment cannot rely lifestyle changes should precisely as it for individuals normal weight. Another popular research topic years been circadian rhythm disorders. disorders are confirmed pro-carcinogenic factor an element that accelerate diagnosis. Conclusions: Understanding cancer, primarily molecular mechanisms essential developing effective preventive therapeutic strategies reduce obese patients.

Language: Английский

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Impact of Circadian Clock PER2 Gene Overexpression on Rumen Epithelial Cell Dynamics and VFA Transport Protein Expression

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(22), P. 12428 - 12428

Published: Nov. 19, 2024

The circadian gene

Language: Английский

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