Endocrine Disruptors and Their Impact on Quality of Life: A Literature Review

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: May 11, 2025

Endocrine-disrupting chemicals (EDCs) are widespread environmental contaminants that interfere with hormonal regulation, affecting metabolism, reproduction, neurodevelopment, and overall health. This review presents an overview of recent evidence on the health effects biological mechanisms EDCs, a focus their impact balance quality life. An integrative literature was conducted using 28 peer-reviewed articles published between 2020 2025, retrieved from databases such as PubMed, Scopus, ScienceDirect. The selected studies explored physiological pathological EDCs in humans. Compounds, bisphenol A, phthalates, polychlorinated biphenyls (PCBs), can mimic or block hormones, disrupt endocrine signaling pathways, bioaccumulate tissues. Exposure, especially during critical developmental windows, is linked to metabolic disorders, infertility, neurodevelopmental delays, hormone-sensitive cancers. Common exposure sources include food, air, household dust, water, personal care products. Key action involve receptor binding interference, oxidative stress, epigenetic alterations. pose significant growing threat public health, warranting urgent regulatory measures, increased awareness, continued research mitigate long-term consequences.

Language: Английский

Disruptores endocrinos: Sustancias ocultas en la vida diaria que afectan el equilibrio hormonal

Investigación y Ciencia de la Universidad Autónoma de Aguascalientes, Journal Year: 2024, Volume and Issue: 93

Published: Sept. 30, 2024

El sistema endocrino (SE) es responsable del buen funcionamiento organismo controlando el metabolismo, reproducción, crecimiento, y estado de ánimo. Éste está formado por órganos como la hipófisis, tiroides, paratiroides, glándula pineal adrenales, que, junto con otras células en otros órganos, regulan funciones fisiológicas mediante secreción hormonas. Sin embargo, SE puede verse alterado factores edad, medio ambiente, estrés, genética algunas sustancias a las que estamos expuestos (llamadas disruptores endocrinos, DE). Los DE están presentes una amplia gama productos cosméticos, alimentos, uso personal, textiles, etc. La exposición estas generar un grave daño tener efectos adversos salud largo plazo.