Case Ascertainment of Measles during a Large Outbreak—Laboratory Compared to Epidemiological Confirmation DOI Creative Commons
Chen Stein‐Zamir,

Nitza Abramson,

Irina Sokolov

et al.

Diagnostics, Journal Year: 2024, Volume and Issue: 14(9), P. 943 - 943

Published: April 30, 2024

Measles is a highly contagious viral disease, and hence, sufficient herd immunity obligatory to prevent infection transmission. still cause of considerable disease burden globally, mainly in children. During national measles outbreak Israel 2018-2019, the peak incidence rates occurred Jerusalem district. Most cases district (75.5%, 1702) were observed children younger than 15 years age, 49.2% (1109) under 5 18.9% (425) infants 1 year age. The routine vaccination schedule includes two doses at 6 (1828, 81.1%) unvaccinated (zero vaccine doses). These comprised 425 affected who ineligible for vaccination, along with 1403 over otherwise unvaccinated. This study aimed describe epidemiologic laboratory features this outbreak, investigate case ascertainment (laboratory confirmed compared epidemiologically cases). population included 2254 notified during period spanning June 2018 May 2019 (incidence rate 176 per 10,000 population). Of cases, 716 (31.8%) confirmed, 1538 (68.2%) as linked. (420, 58.7%) underwent real-time PCR tests. Serological tests (measles IgM IgG) used 189 (26.4%) combination RT-PCR serology was 107 (14.9%) cases. In multivariate model analysis, variables significantly associated (after adjustment) higher odds confirmation month onset (late), additional household (single case), place medical treatment (hospital; either emergency department, or hospitalization) status (at least one prior dose). described demonstrates urgency addressing gaps appropriate prevention programs. road elimination needs be paved robust public health infrastructure, excellent field epidemiology surveillance, investigation, control, proficiency.

Language: Английский

Trends in Neonatal Vaccination: A Ten-year Retrospective Study in a Large Delivery Center DOI

Maria Laura Mourão,

A. Baca-Arzaga,

M. Castellanos

et al.

The Pediatric Infectious Disease Journal, Journal Year: 2025, Volume and Issue: 44(2S), P. S97 - S100

Published: Feb. 1, 2025

Background: Newborns are at increased risk of vaccine preventable morbidity and mortality. The American Academy Pediatrics recommends administering the birth dose hepatitis B (HBV) between 0 30 days life [based on weight (BW) < 2000 g vs. ≥ g], followed by several vaccines 2 months age (regardless BW) including first pneumococcal (PCV). However, adherence to these guidelines is often suboptimal, resulting in incomplete or delayed vaccination. Methods: This a 10-year retrospective, single-center observational study examining rates timeliness HBV PCV vaccination infants admitted mother-baby unit neonatal intensive care (NICU) from 2013 2023. Multinomial logistic regression was used examine factors associated with status. Results: (n = 4935) significantly more likely diverge recommendations versus 49,857). Factors higher relative included administration pre-COVID prepandemic era, prematurity, BW Black/African race, latter two also being discharge. For PCV, Hispanic patients were be discharged compared non-Hispanic patients. Conclusions: Postpandemic, there lower vaccinations, possibly reflecting awareness among parents providers. Preterm status key factor influencing timeliness. Perceptions attitudes toward early-life vaccination, potential racial biases, should examined as contributors differing practices.

Language: Английский

Citations

0
Impact of COVID-19 pandemic on routine childhood vaccinations DOI Open Access

Shi-Rong Lv,

Mingke Wang,

Xue-Lu Yu

et al.

World Journal of Virology, Journal Year: 2024, Volume and Issue: 13(2)

Published: June 24, 2024

Routine pediatric vaccination is one of the most effective public health inter-ventions for control a number fatal diseases. However, during coronavirus disease 2019 pandemic, routine rates were severely affected by disruptions services and vaccine confidence issues. Governments United Nations have taken measures to re-establish vaccination, while additional efforts are needed catch up develop plans ensure future pandemics.

Language: Английский

Citations

1
Vaccine hesitancy among parents of children in their first two years of life DOI Creative Commons

Ruth Magyar,

Peter Voitl, Julian J. M. Voitl

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Sept. 19, 2024

Vaccine hesitancy is considered a primary cause of outbreaks vaccine-preventable infectious diseases. The Austrian vaccination plan includes 24 vaccinations in the first 2 years life, 12 for free and subject to fee. Since preterm babies are more susceptible severe infections, immunization vital protection strategy. This study examines routine schedule recommended children Austria, number timely vaccinations, delayed rejected vaccinations. Possible reasons delays rejection potential influencing factors (preterm birth, COVID-19 pandemic, information sources) also analyzed.

Language: Английский

Citations

1
Case Ascertainment of Measles during a Large Outbreak—Laboratory Compared to Epidemiological Confirmation DOI Creative Commons
Chen Stein‐Zamir,

Nitza Abramson,

Irina Sokolov

et al.

Diagnostics, Journal Year: 2024, Volume and Issue: 14(9), P. 943 - 943

Published: April 30, 2024

Measles is a highly contagious viral disease, and hence, sufficient herd immunity obligatory to prevent infection transmission. still cause of considerable disease burden globally, mainly in children. During national measles outbreak Israel 2018-2019, the peak incidence rates occurred Jerusalem district. Most cases district (75.5%, 1702) were observed children younger than 15 years age, 49.2% (1109) under 5 18.9% (425) infants 1 year age. The routine vaccination schedule includes two doses at 6 (1828, 81.1%) unvaccinated (zero vaccine doses). These comprised 425 affected who ineligible for vaccination, along with 1403 over otherwise unvaccinated. This study aimed describe epidemiologic laboratory features this outbreak, investigate case ascertainment (laboratory confirmed compared epidemiologically cases). population included 2254 notified during period spanning June 2018 May 2019 (incidence rate 176 per 10,000 population). Of cases, 716 (31.8%) confirmed, 1538 (68.2%) as linked. (420, 58.7%) underwent real-time PCR tests. Serological tests (measles IgM IgG) used 189 (26.4%) combination RT-PCR serology was 107 (14.9%) cases. In multivariate model analysis, variables significantly associated (after adjustment) higher odds confirmation month onset (late), additional household (single case), place medical treatment (hospital; either emergency department, or hospitalization) status (at least one prior dose). described demonstrates urgency addressing gaps appropriate prevention programs. road elimination needs be paved robust public health infrastructure, excellent field epidemiology surveillance, investigation, control, proficiency.

Language: Английский

Citations

0