Current Prospective of Hypertension Disease and their Future Aspects in Different Stage of Female Health DOI Creative Commons

Vishal Dixit,

Anamika Anamika,

Shivanand M. Patil

et al.

Journal for Research in Applied Sciences and Biotechnology, Journal Year: 2024, Volume and Issue: 3(6), P. 60 - 67

Published: Dec. 27, 2024

Cardiovascular disease is the primary cause of mortality in women. Due to age and worsening risk factors over menopausal transition, coronary heart events increases postmenopausal women with diabetes. Randomized studies have conflicted regarding beneficial impact estrogen therapy upon intermediate cardiovascular markers events. Therefore, not currently recommended for indications other than symptom management. However, at low adverse events, can be used minimize symptoms. The estimated using engines calculation breast cancer conjunction screening tools such as mammography. Use therapy, statins, anti-platelet agents guided by calculators particularly younger Risk management remains focused lifestyle behaviors achieving optimal levels factors, including lipids, glucose, blood pressure. pharmacologic therapies address these specific hypoglycemic agents, may provide some additional benefit prevention. minimal limited life expectancy complications intensive should also considered.

Language: Английский

Review on Allopurinol in the Treatment of Gout DOI Creative Commons

Aryan Aryan,

Vandana Sahani,

Shivanand M. Patil

et al.

Journal for Research in Applied Sciences and Biotechnology, Journal Year: 2024, Volume and Issue: 3(6), P. 68 - 74

Published: Dec. 27, 2024

Gout and pain are synonymous, a study in this issue of the BJP reports novel anti-nociceptive effect allopurinol, drug most commonly used to treat gout. Allopurinol works by inhibiting xanthine oxidase (XO), enzyme responsible for converting hypoxanthine uric acid which is deposited as crystals joints gout sufferers. Hypoxanthine metabolite of, possible precursor to, adenosine. find that acute inhibition XO with allopurinol produces modest adenosine A1 receptor-mediated common tests chemical thermal nociception mice. A concomitant increase cerebrospinal fluid levels supports their hypothesis increases via salvage from hypoxanthine. Elevating endogenous metabolism well-established strategy producing anti-nociception many preclinical models, but likely be particularly beneficial some chronic states because pro-nociceptive reactive oxygen species produced activity. Thus, may have unexpected benefits associated inflammation, diabetes vascular dysfunction.

Language: Английский

Citations

0
Current Prospective of Hypertension Disease and their Future Aspects in Different Stage of Female Health DOI Creative Commons

Vishal Dixit,

Anamika Anamika,

Shivanand M. Patil

et al.

Journal for Research in Applied Sciences and Biotechnology, Journal Year: 2024, Volume and Issue: 3(6), P. 60 - 67

Published: Dec. 27, 2024

Cardiovascular disease is the primary cause of mortality in women. Due to age and worsening risk factors over menopausal transition, coronary heart events increases postmenopausal women with diabetes. Randomized studies have conflicted regarding beneficial impact estrogen therapy upon intermediate cardiovascular markers events. Therefore, not currently recommended for indications other than symptom management. However, at low adverse events, can be used minimize symptoms. The estimated using engines calculation breast cancer conjunction screening tools such as mammography. Use therapy, statins, anti-platelet agents guided by calculators particularly younger Risk management remains focused lifestyle behaviors achieving optimal levels factors, including lipids, glucose, blood pressure. pharmacologic therapies address these specific hypoglycemic agents, may provide some additional benefit prevention. minimal limited life expectancy complications intensive should also considered.

Language: Английский

Citations

0