In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells DOI Creative Commons
Seokmuk Park,

Han Woong Park,

Dae Bang Seo

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Dec. 3, 2024

Scalp hair plays a crucial role in social communication by expressing personal appearance and self-identity. Consequently, loss often leads to perception of unattractiveness, negatively impacting an individual's life mental health. Currently, the use Food Drug Administration (FDA)-approved drugs for is associated with several side effects, highlighting need identifying new drug candidates, such as plant-derived phytochemicals, overcome these issues.

Language: Английский

Innovative Phytochemicals Based In-Silico Drug Design and Molecular Dynamics Simulation Targeting Norovirus Induced Gastroenteritis DOI

Siddiq Ur Rahman,

Roman Akbar,

Lianting Hu

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141733 - 141733

Published: Feb. 1, 2025

Language: Английский

Citations

1

Adenocarpine, Marmesin, and Lycocernuine from Ficus benjamina as Promising Inhibitors of Aldose Reductase in Diabetes: A Bioinformatics-Guided Approach DOI
M. Oliur Rahman, Sheikh Sunzid Ahmed,

Ali S. Alqahtani

et al.

Applied Biochemistry and Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Language: Английский

Citations

0

Bioactive compounds and cancer prevention: a nutritional approach DOI
Sarra Akermi, Moufida Chaari, Khaoula Elhadef

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 257 - 270

Published: Jan. 1, 2025

Language: Английский

Citations

0

Exploring the therapeutic potential of Rhododendron anthopogon D.Don essential oil constituents against lung cancer: A network pharmacology-based analysis with molecular docking and experimental studies DOI

Zahid Ahmed Mangral,

B Bhat,

Shagufta Sheikh

et al.

Computers in Biology and Medicine, Journal Year: 2025, Volume and Issue: 187, P. 109827 - 109827

Published: Feb. 11, 2025

Language: Английский

Citations

0

Future Trends and Conclusion on Bioactive Phytochemicals in By-products from Leaf, Stem, Root, and Tuber Vegetables DOI
Mohamed Fawzy Ramadan

Published: Jan. 1, 2025

Language: Английский

Citations

0

Antioxidant and antidiabetic activities of Gossypium barbadense L. leaves using in vitro, and in silico methods DOI
Adesoji Alani Olanrewaju, Akingbolabo Daniel Ogunlakin,

Deborah Olayinka Ogundele

et al.

Vegetos, Journal Year: 2025, Volume and Issue: unknown

Published: May 15, 2025

Language: Английский

Citations

0

ASSESSING THYROID FUNCTION: A REVIEW OF BIOCHEMICAL MARKERS AND TESTING STRATEGIES DOI Open Access
Narjes Maged Jasem,

S. Kadhim,

Mohammed M. Sharba

et al.

International Journal of Medical Science and Dental Health, Journal Year: 2024, Volume and Issue: 10(02), P. 130 - 150

Published: Feb. 29, 2024

The present work provides an in depth look at the biochemical markers and testing strategies employed appraising thyroid function. It involves primary hormones such as TSH, T3, T4 that are responsible for homeostasis diagnosis of dysfunction thyroid. assessment also covers evaluates different methods approaches to examine function which include immunoassays mass spectrometry. review offers summary advantages disadvantages increase knowledge facilitate decision making regarding function, improve quality care thyroid-related conditions.

Language: Английский

Citations

3

Antibacterial Potential of Bio-Synthesized Gold Nanoparticles Against MDR Bacteria DOI Open Access

Hadeer Hassan Ibrahim,

Lubna Abdulazeem,

Najwan Kadhim Imran

et al.

International Journal of Medical Science and Dental Health, Journal Year: 2024, Volume and Issue: 10(03), P. 24 - 33

Published: March 17, 2024

The treatment of bacterial and viral infections with antibiotics is a route which rapidly becoming more difficult to achieve. start the twentieth century was infectious disease as leading cause for mortality worldwide. These diseases were treatable, time, antibiotic development research coming fore in medical focus at this time. However, As usage expanded they incorporated into other areas human work, bacterium strains resistant started appear. genes that code resistance are not readily lost once have developed population, addition ongoing growth resistance. join genome become stable part it after integration. Treatment can successfully address multi-drug condition gets provide new mechanisms emerge. Antibiotic occur through many ways, such release large amounts environment during waste water treatment, pharmaceutical manufacturing, presence antibacterial agents soaps products. Exposure air exhaled from animal housing or discharged transportation; ingesting contaminated water; contact diseased farm workers meat processors. scenarios raise an important issue; there great need enhancement existing technology techniques field drug development, well pressing requirement innovative methods diseases. A long-term material these problems will be used foundation further fields has goal priorities. answer problem may lie relatively discovery antimicrobial nanomaterials, against pathogens cannot able develop mechanism. nanomaterials themselves would act precisely engineered plat forms drugs delivered target physiological sites.

Language: Английский

Citations

2

DIAGNOSTIC APPROACHES FOR SEXUALLY TRANSMITTED INFECTIONS IN CLINICAL MICROBIOLOGY: A COMPREHENSIVE REVIEW DOI Open Access
Zahraa Falah Azeez, Z. Al-Saadi, Qusay .K.M.AL Masood

et al.

International Journal of Medical Science and Dental Health, Journal Year: 2024, Volume and Issue: 10(02), P. 01 - 16

Published: Feb. 6, 2024

Accurate and timely diagnostic methods for the management of sexually transmitted infections (STIs) are very esssential because such diseases pose a big threat to public health. This systematic review gives detailed overview wide range approaches, technologies, challenges future possible ways in STI diagnosis. A traditional laboratory methods, nucleic acid amplification tests (NAATs), point-of-care testing (POCT) also new technologies discuss their significant contributions revolution diagnostics. Challenges including antimicrobial resistance, evolving pathogens poor access quality assurance have been identified which highlights need continued interventions aimed at addressing these challenges. Over horizon, integrated syndromic approaches further development as well precision medicine strategies based on novel biomarkers technology present many exciting possibilities improving accuracy, accessibility, diagnoses usefulness. seeks guide current practices clinical microbiology toward diagnosis, highlighting innovations that key patient welfare advancements health efforts against STIs.

Language: Английский

Citations

1

The Microbiological Landscape of Diabetic Foot Infections: Implications for Treatment and Prevention DOI Open Access
Reem A. Mansour,

Doaa A. Abdulwaha

International Journal of Medical Science and Dental Health, Journal Year: 2024, Volume and Issue: 10(02), P. 65 - 85

Published: Feb. 15, 2024

Diabetic foot infections (DFIs) represent one of the most serious and frequent complications resulting from diabetes mellitus, causing substantial morbidity as well enhanced risk for amputation. The microbiological world DIFs is typically multifaceted usually includes a polymicrobial community with both aerobic bacteria this anaerobe purpose review to decompose current knowledge about microbial diversity in DFIs, their resistance patterns biofilms contribution resilience towards infection persistence therapy. Development molecular techniques has allowed increased insight into DFI microbiome, not only uncovering prevalent pathogens such Staphylococcus aureus Pseudomonas aeruginosa but also lesser frequently isolated organisms. employment multidrug-resistant organisms intricate relationship between species within present management challenges. focuses on relevance early accurate diagnosis using culture-based methodologies methods that, turn, would enable more specific antimicrobial Moreover, opportunity new antibacterial agents will be available; other local delivery systems adjunctive therapies like negative pressure wound therapy addressed. Strategies prevention that involve patient education, regular checks proper glycemic control form part essential measures reducing incidences DFIs. An interdisciplinary approach care highlighted review, influencing diabetology specialists, infectious disease physicians microbiologists podiatrists able improve treatment outcomes. This aims provide recent synthesis aspects DFIs clinical implications, an intent informing development effective strategies thus improving patient’s quality life health systems.

Language: Английский

Citations

1