The dynamics of thrombolysis over time in acute immunologic reactions

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 2, 2025

Allergic reactions and angioedema are important immunologic conditions in acute care settings. Prior data indicate an association between symptom severity maximum lysis (ML) thromboelastometry. We aimed to evaluate the dynamics of ML two hours after admission emergency department. determined with thromboelastometry using extrinsic testing (EXTEM, ROTEM®, Werfen GmbH, Munich, Germany) at presentation patients approximately thereafter (after observation interval). The median test was used compare extent individuals who were still symptomatic interval those asymptomatic. prospectively enrolled 16 (10 (63%) female, mean age 50 ± 14 years). Of these, 6 (38%) interval. These that time had significantly higher than asymptomatic (14% (IQR 12–17) vs. 8% 4–10), p = 0.002). To conclude, department reactions, symptoms 2 h may be associated alterations ML.

Language: Английский

Impact of the COVID-19 Pandemic on the Use of Public Access Defibrillation Systems: A Systematic Review and Meta-analysis

Eurasian Journal of Emergency Medicine, Journal Year: 2024, Volume and Issue: 23(1), P. 61 - 69

Published: March 1, 2024

Aim: This meta-analysis presented the impact of pandemic Coronavirus disease-2019 on use public access defibrillation (PAD) system for adult patients with out-of-hospital cardiac arrest. Materials and Methods:This study was designed as a systematic review is reported in accordance Preferred Reporting Items Systematic Reviews Meta-Analysis guidelines.We systematically searched PubMed, Medline, Embase, Cochrane Central Register Controlled Trials databases until January 2024.Results: included 30 analyzed studies.Pooled analysis showed that activation PAD among those two periods varied amounted to 3.8% vs. 3.9%, respectively [odds ratio (OR)=0.77;95% confidence interval (CI): 0.66 0.89; p<0.001].There were no statistically significant differences using automated external defibrillators (AEDs) when comparing period prepandemic (5.0% 6.2%;OR=0.78; 95% CI: 0.57 1.07; p=0.12). Conclusion:The data indicate substantial decrease during pandemic.Furthermore, there variations usage shock AEDs, suggesting AEDs remained similar pre-pandemic they available.It essential promote bystanders perform societal initiatives achieve this objective.

Language: Английский

Reassessment of the underlying mechanisms that contribute to the neurological disorders linked to long-term COVID-19

Disaster and Emergency Medicine Journal, Journal Year: 2024, Volume and Issue: 9(2), P. 129 - 130

Published: June 14, 2024

We read with great interest the article by Graban and his colleagues [1] regarding neurological effects of long COVID-19.A possible explanation for difficulties was proposed authors as cell fusion.Furthermore, highlight that there is a considerable percentage people feeling weariness cognitive dysfunction, which includes lower attention span, short-term memory loss, overall impairment.Moreover, recent scientific findings suggest are increasingly severe problems follow these symptoms.There disparities in intelligence quotient (IQ) between those who have been infected SARS-CoV-2 not contracted illness.Even little illness can result decrease IQ around three points [2].Nevertheless, it important to note most investigations were carried

Language: Английский