Chronic endometritis and infertility — in vitro fertilization outcomes: systematic review and meta-analysis DOI Creative Commons
Vyacheslav Lokshin, И. И. Куценко, И. О. Боровиков

et al.

Kuban Scientific Medical Bulletin, Journal Year: 2023, Volume and Issue: 30(5), P. 15 - 40

Published: Oct. 26, 2023

Background. The relevance of the problem is related to high prevalence chronic endometritis (CE); its role in female infertility, implantation failures during assisted reproductive technology procedures, and recurrent miscarriage; as well lack a unified strategy diagnosis treatment this pathology. present systematic review with meta-analysis focuses on evaluating impact CE therapy outcome vitro fertilization. In addition, effect various severity outcomes technologies analyzed. Objective . To analyze varying Methods Using PubMed, Medline, Scopus, Embase, ELibrary, Cochrane Central Register Controlled Trials (CENTRAL), WHO International Clinical Registry, Russian Science Citation Index, search was conducted for articles published over past 12 years that met following criteria: randomized controlled trial examining fertility ways treat it. indicators were calculated: ongoing pregnancy/live birth, clinical pregnancy, miscarriage rates. A total 4145 patients (from ten studies) included. performed using Stata 11.0 software (The Collaboration, Oxford, UK). heterogeneity considered low at I 2 <30%, moderate 30–50%, >50%. Results Women exhibited lower birth (OR 1.97; p = 0.02) pregnancy rates 2.28; 0.002) compared women without increased 5.33; < 0.0001) 3.64; 0.0001). fertilization comparable treated (ongoing rate, rate: ns). severe 0.43; 0.003) 0.40; 0.0007). Mild showed no significant pregnancy/ live Conclusion significantly reduces infertile undergoing Noteworthy antimicrobial such improves results technologies, which are those CE. negative pathology capacity endometrium most often observed form, while mild form has virtually outcome.

Language: Английский

Correlation of hysteroscopic findings of chronic endometritis with CD138 immunohistochemistry and their correlation with pregnancy outcomes DOI

J. Dang,

Xifeng Xiao,

Mao Li

et al.

Journal of Assisted Reproduction and Genetics, Journal Year: 2024, Volume and Issue: 41(9), P. 2477 - 2483

Published: Sept. 1, 2024

Language: Английский

Citations

0
Chronic endometritis and fertility: still a debatable issue DOI Creative Commons
Mete Işıkoğlu,

Akif Çiftçioğlu,

Ayşenur Avcı

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 2, 2024

Abstract Purpose: We conducted this study to help elucidate the clinical relevance of CE with fertility. Methods: Prospective cohort including 60 patients undergoing hysteroscopy for various indications were triaged into three arms: a history implantation failure in IVF treatment constructed first arm (#25), second included recurrent pregnancy loss (#20) and third group confined H/S other (#15). Endometrial sampling was performed all cases prior starting procedure. Results: Baseline characteristics, demographic variables percentage healthy deliveries similar groups. Twenty six (43%) diagnosed based on histopathologic assessment, endometrial culture results positive only two (3.3%) cases. We found no difference incidence among Conclusion: CE may be probable reasons reproductive disorders but strenous investigations should reserved limited whereas more have been excluded.

Language: Английский

Citations

0
Revolutionizing chronic endometritis diagnosis: real-time polymerase chain reaction unveils microbial pathogens in Indian women with abnormal bleeding and reproductive challenges DOI Creative Commons
Murugan Nandagopal,

Rajesh Rajan N,

Chirayu Padhiar

et al.

AJOG Global Reports, Journal Year: 2024, Volume and Issue: 4(3), P. 100377 - 100377

Published: July 6, 2024

This study aimed to assess the utility of real-time-polymerase chain reaction (PCR) for diagnosing chronic endometritis (CE) by targeting 11 prevalent pathogens and compare outcomes with conventional culture-based diagnosis.

Language: Английский

Citations

0
Chronic endometritis and infertility — in vitro fertilization outcomes: systematic review and meta-analysis DOI Creative Commons
Vyacheslav Lokshin, И. И. Куценко, И. О. Боровиков

et al.

Kuban Scientific Medical Bulletin, Journal Year: 2023, Volume and Issue: 30(5), P. 15 - 40

Published: Oct. 26, 2023

Background. The relevance of the problem is related to high prevalence chronic endometritis (CE); its role in female infertility, implantation failures during assisted reproductive technology procedures, and recurrent miscarriage; as well lack a unified strategy diagnosis treatment this pathology. present systematic review with meta-analysis focuses on evaluating impact CE therapy outcome vitro fertilization. In addition, effect various severity outcomes technologies analyzed. Objective . To analyze varying Methods Using PubMed, Medline, Scopus, Embase, ELibrary, Cochrane Central Register Controlled Trials (CENTRAL), WHO International Clinical Registry, Russian Science Citation Index, search was conducted for articles published over past 12 years that met following criteria: randomized controlled trial examining fertility ways treat it. indicators were calculated: ongoing pregnancy/live birth, clinical pregnancy, miscarriage rates. A total 4145 patients (from ten studies) included. performed using Stata 11.0 software (The Collaboration, Oxford, UK). heterogeneity considered low at I 2 <30%, moderate 30–50%, >50%. Results Women exhibited lower birth (OR 1.97; p = 0.02) pregnancy rates 2.28; 0.002) compared women without increased 5.33; < 0.0001) 3.64; 0.0001). fertilization comparable treated (ongoing rate, rate: ns). severe 0.43; 0.003) 0.40; 0.0007). Mild showed no significant pregnancy/ live Conclusion significantly reduces infertile undergoing Noteworthy antimicrobial such improves results technologies, which are those CE. negative pathology capacity endometrium most often observed form, while mild form has virtually outcome.

Language: Английский

Citations

0