Increased monocytes and their derived indicators are associated with clinical severity of acute heart failure following acute myocardial infarction DOI Creative Commons
Xinlin Xiong, Min An, Yuan Li

et al.

Frontiers in Cardiovascular Medicine, Journal Year: 2025, Volume and Issue: 12

Published: April 10, 2025

Monocytes play a significant role in the pathophysiology of acute myocardial infarction (AMI). The relationship between monocytes, their derived indicators, and severity heart failure following AMI remains unclear. Therefore, this study aims to investigate association monocytes indicators with clinical patients AMI. In total 173 were enrolled retrospective study. demographic data relevant medical histories obtained. lipid levels measured. All divided into two groups based on killip classification. Killip class III-IV was defined as severe failure, while I-II non-severe failure. Monocyte count, monocyte-to-white blood cell ratio, monocyte-to-lymphocyte ratio significantly higher compared those (P < 0.05). Multivariate logistic regression analysis showed that monocyte independently associated Moreover, linked NT-proBNP concentrations Receiver-operating characteristic curve could identify some extent elevation correlated AMI, offered potential discriminating value for cardiogenic pulmonary edema shock

Language: Английский

Increased monocytes and their derived indicators are associated with clinical severity of acute heart failure following acute myocardial infarction DOI Creative Commons
Xinlin Xiong, Min An, Yuan Li

et al.

Frontiers in Cardiovascular Medicine, Journal Year: 2025, Volume and Issue: 12

Published: April 10, 2025

Monocytes play a significant role in the pathophysiology of acute myocardial infarction (AMI). The relationship between monocytes, their derived indicators, and severity heart failure following AMI remains unclear. Therefore, this study aims to investigate association monocytes indicators with clinical patients AMI. In total 173 were enrolled retrospective study. demographic data relevant medical histories obtained. lipid levels measured. All divided into two groups based on killip classification. Killip class III-IV was defined as severe failure, while I-II non-severe failure. Monocyte count, monocyte-to-white blood cell ratio, monocyte-to-lymphocyte ratio significantly higher compared those (P < 0.05). Multivariate logistic regression analysis showed that monocyte independently associated Moreover, linked NT-proBNP concentrations Receiver-operating characteristic curve could identify some extent elevation correlated AMI, offered potential discriminating value for cardiogenic pulmonary edema shock

Language: Английский

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