Social isolation consequences: lessons from COVID-19 pandemic in a context of dynamic lock-down in Chile DOI Creative Commons
Alessandra Patrono, Stefano Renzetti,

Cristian Guerini

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 28, 2023

Abstract Background: Chile did not adopt general and unified lockdowns for the whole nation but organized itself with dynamic sometimes irregular lockdowns. These dynamics consequences of social isolation could be generalized to other contexts such as those affecting minorities immigrants, prisoners, refugees. Methods: In this study, we investigated physical mental health symptoms associated lifestyle changes due lockdown among university students in Chile. We examined psychopathological variations relation problems a healthy young population. Our goal was develop interventions address these new psychosocial potentially comparable post-pandemic contexts. From May 10th 2021 June 2th 2021, 420 University took part an anonymous survey asking information on habits that emerged during response COVID-19 pandemic. Three outcomes were assessed: digestive disorders; headache; fear COVID-19. Covariates including conditions pandemic, SARS-CoV-2 infections family, financial situation productivity considered analysis. Results: Participants experienced headache quite frequently period. More than half sample also isolation. Female gender, sleep quality, memory difficulties, change eating resulted increased risk headaches disorders. Conclusions: The results study fit within original pandemic context: can help identify needs promote solutions applicable different Future should focus promotion implementation focused hygiene, psychoeducation use mobile devices gender medicine support healthcare organizations University.

Language: Английский

Determinants of health-related quality of life in healthy children and adolescents during the COVID-19 pandemic: Results from a prospective longitudinal cohort study DOI Creative Commons
Sarah R. Haile, Gabriela P. Peralta, Alessia Raineri

et al.

European Journal of Pediatrics, Journal Year: 2024, Volume and Issue: 183(5), P. 2273 - 2283

Published: Feb. 27, 2024

Abstract Understanding health-related quality of life (HRQOL) in children and adolescents, during a pandemic afterwards, aids understanding how circumstances their lives impact well-being. We aimed to identify determinants HRQOL from broad range biological, psychological, social factors large longitudinal population-based sample. Data was taken sample ( n = 1843) adolescents enrolled the prospective school-based cohort study Ciao Corona Switzerland. The primary outcome HRQOL, assessed using KINDL total score its subscales (each 0, worst, 100, best). Potential determinants, including biological (physical activity, screen time, sleep, etc.), psychological (sadness, anxiousness, stress), (nationality, parents’ education, etc.) factors, were 2020 2021 2022. Determinants identified data-driven manner recursive partitioning define homogeneous subgroups, stratified by school level. Median empirically subgroups ranged 68 83 69 82 secondary school. sadness, stress as most important both children. Other such physical chronic health conditions, or nationality, only individual subscales. Conclusion : Recent mental health, more than physical, played key role determining times. Public strategies improve may therefore be effective improving this age group. What is Known: • Assessing complex construct, involving factors. Factors driving are not often studied samples. New: Mental (stress, sadness) coronavirus pandemic,

Language: Английский

Citations

4
Health-Related Quality of Life and Adherence to Physical Activity and Screen Time Recommendations in Schoolchildren: Longitudinal Cohort Ciao Corona DOI Creative Commons
Sarah R. Haile, Samuel Gunz, Gabriela P. Peralta

et al.

International Journal of Public Health, Journal Year: 2023, Volume and Issue: 68

Published: July 19, 2023

Objectives: We investigated changes in adherence to physical activity (PA) and screen time (ST) recommendations of children adolescents throughout the pandemic, their association with health-related quality life (HRQOL). Methods: 1,769 primary (PS, grades 1-6) secondary (SS, 7-9) school from Ciao Corona, a school-based cohort study Zurich, Switzerland, five questionnaires 2020-2022. HRQOL was assessed using KINDL questionnaire. PA (≥60 min/day moderate-to-vigorous PA) ST (≤2 h/day ST) followed WHO guidelines. Results: Adherence dropped 2020 (83%-59% PS, 77%-52% SS), but returned pre-pandemic levels by 2022 (79%, 66%). Fewer met (74% 29% SS) 2021 (82%, 37%) than (95%, 68%). decreased 3 points between 2022, 9.7 higher (95% CI 3.0-16.3) March who both versus no recommendations. Conclusion: guidelines on during pandemic had consistent despite longitudinal behavior.

Language: Английский

Citations

8
Persistent humoral immune response in youth throughout the COVID-19 pandemic: prospective school-based cohort study DOI Creative Commons
Alessia Raineri, Thomas Radtke,

Sonja Rueegg

et al.

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Nov. 27, 2023

Language: Английский

Citations

5
Health-related quality of life in children and adolescents born very preterm and its correlates: a cross-sectional study DOI Creative Commons
Sarah R. Haile, Gabriela P. Peralta, Mark Adams

et al.

BMJ Paediatrics Open, Journal Year: 2024, Volume and Issue: 8(1), P. e002885 - e002885

Published: Oct. 1, 2024

We aimed to assess health-related quality of life (HRQOL) in a cohort very preterm born children and adolescents (aged 5-16), compare it with their fullterm siblings the general population. also explored correlates HRQOL among born.

Language: Английский

Citations

1
SARS-CoV-2 seroprevalence and determinants for salivary seropositivity among pupils and school staff: a prospective cohort study DOI Creative Commons
Joanna Merckx, Milena Callies,

Ines Kabouche

et al.

Epidemiology and Infection, Journal Year: 2023, Volume and Issue: 151

Published: Jan. 1, 2023

Abstract Representative school data on SARS-CoV-2 past-infection are scarce, and differences between pupils staff remain ambiguous. We performed a nation-wide prospective seroprevalence study among over time in relation to determinants of infection using Poisson regression generalised estimating equations. A cluster random sample was selected with allocation by region sociodemographic (SES) background. Surveys saliva samples were collected December 2020, March, June 2021, also October 2021 for primary pupils. recruited 885 569 secondary 799 84 schools. Cumulative (95% CI) increased from 11.0% (7.6; 15.9) at baseline 60.4% (53.4; 68.3) 2021. Group estimates similar baseline; however, they significantly higher (38.9% (32.5; 46.4)) compared (24.2% (20.3; 28.8)). Infections asymptomatic 48–56% 28% staff. Seropositivity associated individual SES pupils, level, language network June. Associations behavioural characteristics inconsistent. Seroconversion rates two- four-fold after self-reported high-risk contacts, especially adults. Seroprevalence studies non-invasive sampling can inform public health management.

Language: Английский

Citations

2
Potential for bias in (sero)prevalence estimates when not accounting for test sensitivity and specificity DOI Creative Commons
Sarah R. Haile

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: July 4, 2023

Abstract Background: The COVID-19 has led to many studies of seroprevalence. A number methods exist in the statistical literature correctly estimate disease prevalence presence diagnostic testmisclassification, but these seem be less known and notroutinely used public health literature. We aimed show how widespread problem is recent publications, quantify magnitude bias introduced when correct are not used. Methods: examined a sample determine often researcher did account for test performance estimates Using straightforward calculations, we estimated amount reporting proportion positive results instead using sensitivity specificity prevalence. Results: Of seroprevalence sampled, 80% failed specificity. Expected more than desired practice, ranging from 1% 10%. Conclusions: Researchers conducting should their analysis.

Language: Английский

Citations

1
Health-related quality of life in children and adolescents born very preterm and its correlates: a cross-sectional study DOI Creative Commons
Sarah R. Haile, Gabriela P. Peralta, Mark Adams

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 29, 2024

Abstract Objective We aimed to assess health-related quality of life (HRQOL) in a cohort very preterm born children and adolescents (aged 5-16), compare it with their fullterm siblings the general population. also explored correlates HRQOL among born. Design Cross-sectional survey Patients Children <32 weeks gestation (N = 442) as well 145) Main outcome measures Primary was KINDL total score (0 worst - 100 best), validated multidimensional measure adolescents. Methods Linear mixed models accounted for family unit. Secondary analysis compared another healthy from same time period. A classification tree potential HRQOL. Results On average, children, both <28 28-31 gestational age, had similar sibling controls (-2.3, 95% CI -3.6 -0.6), population (+1.4, 0.2 2.5). Chronic non-respiratory health conditions (such attention deficit hyperactivity disorder (ADHD) or heart conditions, but not including cerebral palsy), respiratory symptoms affecting daily were key children. Conclusions Very birth associated relevant reduction peers. However, lower explained by other factors, such older presence chronic possibly modifiable current symptoms. The influence symptom amelioration its on needs be investigated further. What is already known this topic As infants become more likely survive, importance increases. Research often focuses non-modifiable risk factors without interventions. study adds that Age, symptoms, Better control could improve How might affect research, practice policy better understanding complex picture pulmonary disease following prematurity throughout interventions treat may leveraged grow.

Language: Английский

Citations

0
Potential for bias in (sero)prevalence estimates when not accounting for test sensitivity and specificity: a systematic review DOI
Sarah R. Haile,

David Kronthaler

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 19, 2024

Abstract Objectives The COVID-19 pandemic has led to many studies of seroprevalence. A number methods exist in the statistical literature correctly estimate disease prevalence or seroprevalence presence diagnostic test misclassification, but these seem be less known and not routinely used public health literature. We aimed examine how widespread problem is recent publications, quantify magnitude bias introduced when correct are used. Design: systematic review was performed often researchers accounted for performance estimates Using straightforward calculations, we estimated amount reporting proportion positive results instead using sensitivity specificity prevalence. Results Of sampled, 78% (95% CI 72–82%) failed account specificity. Expected more than desired practice, ranging from 1–12%. Conclusions Researchers conducting should their analysis.

Language: Английский

Citations

0
Potential for bias in (sero)prevalence estimates when not accounting for test sensitivity and specificity DOI Creative Commons
Sarah R. Haile,

David Kronthaler

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2022, Volume and Issue: unknown

Published: Nov. 29, 2022

Abstract Background The COVID-19 pandemic has led to many studies of seroprevalence. A number methods exist in the statistical literature correctly estimate disease prevalence or seroprevalence presence diagnostic test misclassification, but these seem be less known and not routinely used public health literature. We aimed examine how widespread problem is recent publications, quantify magnitude bias introduced when correct are used. Methods systematic review was performed often researchers accounted for performance estimates Using straightforward calculations, we estimated amount reporting proportion positive results instead using sensitivity specificity prevalence. Results Of sampled, 78% (95% CI 72% 82%) failed account specificity. Expected more than desired practice, ranging from 1% 12%. Conclusions Researchers conducting should their analysis.

Language: Английский

Citations

1
Health-related quality of life and adherence to physical activity and screen time recommendations in schoolchildren: longitudinal cohort Ciao Corona DOI Creative Commons
Sarah R. Haile, Samuel Gunz, Gabriela P. Peralta

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: March 29, 2023

Abstract Objectives We investigated changes in adherence to physical activity (PA) and screen time (ST) recommendations of children adolescents throughout the pandemic, their association with health-related quality life (HRQOL). Methods 1769 primary (PS, grades 1-6) secondary (SS, 7-9) school from Ciao Corona, a school-based cohort study Zurich, Switzerland, 5 questionnaires 2020-2022. HRQOL was assessed using KINDL questionnaire. PA (≥ 60 min/day moderate-to-vigorous PA) ST (≤ 2 hours/day ST) followed WHO guidelines. Results Adherence dropped 2020 (83% 59% PS, 77% 52% SS), but returned pre-pandemic levels by 2022 (79%, 66%). Fewer met (74% 29% SS) 2021 (82%, 37%) than (95%, 68%). decreased 3 points between 2022, 9.7 higher (95% CI 3.0-16.3) March who both versus no recommendations. Conclusions guidelines on during pandemic had consistent despite longitudinal behavior.

Language: Английский

Citations

0