Heliyon,
Journal Year:
2024,
Volume and Issue:
11(1), P. e41588 - e41588
Published: Dec. 31, 2024
Detection
of
biomolecules,
Glutathione
(GSH)
in
particular,
is
important
because
it
helps
assess
antioxidant
capacity,
cellular
protection,
detoxification
processes,
and
potential
disease
associations.
Monitoring
glutathione
levels
can
provide
valuable
information
about
overall
health
well-being.
Many
medical
disorders
have
been
connected
to
levels.
Higher
seen
several
cancer
cell
types,
which
may
increase
their
resistance
radiation
chemotherapy.
be
measured
through
various
methods,
such
as
colorimetric
assays
fluorescent
probes.
However,
surface-enhanced
Raman
scattering
(SERS)
has
known
an
efficient
selective
technique
for
biomolecule
detection.
Here
this
perspective
review,
we
reported
two
distinctive
methods
based
on
SERS
detection
GSH;
heat-induced
method
reversed
reporting
agent
method.
Several
variables
that
impact
the
scheme
were
elaborated
"heat-induced
method,"
including
pretreatment,
nanoparticle
reduction
time,
process
temperature,
pH
colloidal
solution,
concentration
citrate
buffer,
participating
nanoparticles.
To
choose
best
a
reverse
using
approaches,
agents
examined
second
In
order
grasp
situation
at
hand,
detection-specifically,
GSH
schemes-was
briefly
discussed.
spectroscopy
its
associated
terminology
then
covered
followed
by
outlook
end.
meet
demands
real-time
applications
everyday
life
enhance
detection-in
detection-such
thorough
investigation
unavoidable.
Due
to
their
distinctive
physicochemical
characteristics,
nanoparticles
have
drawn
significant
attention
in
a
number
of
sectors
and
biomedical
applications.
However,
worries
about
potential
negative
impact
on
human
health
been
raised
due
growing
use.
This
in-depth
analysis
observes
the
complex
association
between
nanoparticles,
oxidative
stress,
inflammation,
illuminating
underlying
mechanisms
ramifications.
Additionally,
it
describes
sorts
origins
highlighting
rising
prevalence
commonplace
goods
settings.
The
methods
by
which
cause
stress
are
then
explored,
creation
reactive
oxygen
species
(ROS)
harmful
cellular
materials
such
as
lipids,
proteins,
nucleic
acids.
review
also
examines
how
contribute
inflammation
triggering
pro-inflammatory
signaling
pathways
inducing
cytokine
responses.
It
clarifies
functions
antioxidant
enzymes
preventing
formation
free
radicals
generated
nanoparticles.
Heliyon,
Journal Year:
2024,
Volume and Issue:
11(1), P. e41588 - e41588
Published: Dec. 31, 2024
Detection
of
biomolecules,
Glutathione
(GSH)
in
particular,
is
important
because
it
helps
assess
antioxidant
capacity,
cellular
protection,
detoxification
processes,
and
potential
disease
associations.
Monitoring
glutathione
levels
can
provide
valuable
information
about
overall
health
well-being.
Many
medical
disorders
have
been
connected
to
levels.
Higher
seen
several
cancer
cell
types,
which
may
increase
their
resistance
radiation
chemotherapy.
be
measured
through
various
methods,
such
as
colorimetric
assays
fluorescent
probes.
However,
surface-enhanced
Raman
scattering
(SERS)
has
known
an
efficient
selective
technique
for
biomolecule
detection.
Here
this
perspective
review,
we
reported
two
distinctive
methods
based
on
SERS
detection
GSH;
heat-induced
method
reversed
reporting
agent
method.
Several
variables
that
impact
the
scheme
were
elaborated
"heat-induced
method,"
including
pretreatment,
nanoparticle
reduction
time,
process
temperature,
pH
colloidal
solution,
concentration
citrate
buffer,
participating
nanoparticles.
To
choose
best
a
reverse
using
approaches,
agents
examined
second
In
order
grasp
situation
at
hand,
detection-specifically,
GSH
schemes-was
briefly
discussed.
spectroscopy
its
associated
terminology
then
covered
followed
by
outlook
end.
meet
demands
real-time
applications
everyday
life
enhance
detection-in
detection-such
thorough
investigation
unavoidable.
