Role of Acyl-CoA Thioesterase 7 in Regulating Fatty Acid Metabolism and Its Contribution to the Onset and Progression of Bovine Clinical Mastitis DOI Open Access
Bin Zhou, Bohao Zhang, Jin‐Hee Han

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(23), P. 13046 - 13046

Published: Dec. 4, 2024

Clinical mastitis (CM) is a prevalent and severe inflammatory disease in dairy cows affecting the mammary glands. Fatty acid (FA) metabolism associated enzymes are crucial for many physiological pathological processes cows. However, relationships among FA metabolism, FA-associated enzymes, CM, as well mechanisms underlying their interactions, not fully understood. The aim of this study was to characterize biological process (BP) terms, pathways, differentially expressed proteins (DEPs) related from our previous data-independent acquisition proteomic study. Six BPs involving 14 downregulated 20 upregulated DEPs, four pathways 10 11 DEPs synthesis were systematically identified. Associated analysis suggested that 12 candidate obtained especially acyl-CoA thioesterase 7 (ACOT7), regulate long-chain (LCFA) elongation biosynthesis unsaturated FAs. Immunohistochemical immunofluorescence staining results showed ACOT7 present mainly cytoplasm epithelial cells. qRT-PCR Western blotting

Language: Английский

High ω6/ω3 polyunsaturated fatty acid (PUFA) ratio impairs intestinal mucosal barrier function via ROS/TLR4/NF-κB-mediated aberrant expression of tight junction proteins DOI

Shumeng Du,

Rui Li, Yuanfa Liu

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106225 - 106225

Published: Feb. 1, 2025

Language: Английский

Citations

1
Exploring the potential of the agar-based emulsion gel as a pork fat substitute in sausage with a focus on the digestive behaviors of lipids and proteins in vitro DOI
Seonmin Lee, Kyung Jo, Soeun Kim

et al.

Food Hydrocolloids, Journal Year: 2025, Volume and Issue: unknown, P. 111335 - 111335

Published: March 1, 2025

Language: Английский

Citations

1
Enzymatic synthesis of structured phospholipids with ideal ω-6/3 fatty acid ratios via supplementation with α-linolenic acid from silkworm pupae oil DOI
Naoyuki Kamatani,

Jin‐Zheng Wang,

Xinying Wang

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 105952 - 105952

Published: Jan. 1, 2025

Language: Английский

Citations

0
Modulating the nutritional value of Acheta domesticus (house cricket) through the eco-sustainable Ascophyllum nodosum dietary supplementation DOI Creative Commons
Behixhe Ajdini, Irene Biancarosa, Gloriana Cardinaletti

et al.

Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: 140, P. 107263 - 107263

Published: Jan. 27, 2025

Language: Английский

Citations

0
The relationship between serum Omega-6 fatty acids and cardiovascular disease mortality: a competing risks and multivariate Mendelian randomization analysis DOI
Huimin Zhao,

Mingkang Guo,

Changlin Yang

et al.

Clinical Nutrition ESPEN, Journal Year: 2025, Volume and Issue: 66, P. 372 - 380

Published: Jan. 31, 2025

Language: Английский

Citations

0
Dietary Fatty Acids and Antinuclear Antibodies Among Adults with Arthritis in the United States: NHANES 1999–2004 DOI Open Access
Jie Guo, Yifei Yu, Jiaqi Su

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(6), P. 934 - 934

Published: March 7, 2025

Background: This study investigated the link between daily fatty acid intake and antinuclear antibody (ANA) levels, a marker of immune dysregulation autoimmune diseases, in individuals with self-reported arthritis. Methods: From US National Health Nutrition Examination Survey (NHANES) 1999–2004, 829 participants who arthritis had autoantibody measurements were selected. Dietary acids collected via two 24 h dietary recall interviews conducted by trained interviewers. ANA levels measuring IgG autoantibodies targeting cellular antigens. Results: In multi-adjusted logistic model, odds ratio (OR) highest tertile omega-3 (with > 1.60 g/day) for probability positivity was 0.43 (95% CI: 0.19–0.96) compared to those lowest (≤0.92 g/day). However, we did not observe statistically significant results other acids. Conclusions: Our findings highlight potential PUFAs modulate function lower risk

Language: Английский

Citations

0
TOPLU BESLENME HİZMETİNDE DİYETİSYEN FAKTÖRÜ: MENÜ KALİTESİ ÜZERİNE PİLOT BİR ÇALIŞMA DOI Open Access
Murat Gürbüz, Emine Karademir

Published: March 14, 2025

Amaç: Toplu beslenme hizmeti sunan kurumların menülerinin bireylerin günlük enerji ve besin ögesi ihtiyaçlarının önemli bir kısmını karşılaması beklenmektedir. Hizmet kurumlarda meslek profesyonellerinin etkin şekilde rol alması, başarılı sürdürülebilir uygulamaların gerçekleştirilmesinde kilit öneme sahiptir. Bu çalışma, toplu hizmetinde diyetisyen istihdam edenlerle diğer profesyonellerini eden kurumlar arasında, menü planlarının içeriği, besleyicilik değeri sağlığı geliştirici özelliklerinin karşılaştırılmasını amaçlamaktadır. Gereç Yöntemler: Araştırmaya Niğde ilinde (n=3) farklı profesyoneli orta büyük ölçekli toplam altı adet veren kurum dahil edilmiştir. Çalışmada 2024 yılı Ekim ayına ait iki haftalık 60 planı incelenmiştir. Bulgular: Çalışma sonucunda makro ögeleri arasında istatistiksel olarak anlamlı farklılık bulunmamıştır. Ancak planlarında C vitamini, A K B12 iyot demir içeriğinin belirgin düzeyde daha yüksek olduğu saptanmıştır. mikro vitamini düzeylerinin belirlenmiştir (p0.05), ORAC değerlerinin saptanmıştır (p

Citations

0
Transition of clinical biomarker status from childhood into adolescence–A prospective study in children from eight European countries DOI Creative Commons
Anna Floegel, Paola Russo,

Toomas Veidebaum

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0311180 - e0311180

Published: Feb. 3, 2025

Purpose Understanding factors influencing clinical biomarkers is important for the prevention of chronic disease. This study aimed to estimate transitions biomarker status from childhood adolescence and identify determinants in early life a prospective children cohort. Subjects methods Our sample comprised 1295 participating baseline (2007/08) second follow-up examination (2013/14) multi-center IDEFICS ( I dentification D ietary- lifestyle-induced health EF fects n C hildren infant S )/I.Family study. Clinical blood including glycated hemoglobin A1c (HbA1c), high-density lipoprotein cholesterol (HDL-cholesterol), triglycerides, C-reactive protein (CRP), interleukin 6, ferritin, leptin insulin-like growth factor 1 (IGF-1) were repeatedly measured 2007/2008 (age range: 3.0 <10.0 years) 2013/2014. Latent transition analysis was used statuses probabilities; estimated using mixed-effects models. Results Four distinct identified: (1) “normal” (all low/medium; except HDL-cholesterol; reference), (2) “low leptin/IGF-1/HbA1c”, (3) “dyslipidemia/high leptin” (4) “inflammation”. Children classified as leptin/IGF-1/HbA1c” at most likely stay this (89.8%) or change (10%) during follow-up. Compared children, less have family history diabetes (0.26 [0.08;0.86]; odds ratio (OR) 95% confidence interval) hypertension (0.53 [0.29;0.99]) (0.32 [0.27;0.38]) well their mothers (0.93 [0.88;0.98]) had lower BMI. families with low/medium education 55% [9%-119%] higher risk being 49% [1%-121%] “inflammation” compared status. Membership sports club reduced latter risks by 28% [2%-47%] 40% [17%-56%], respectively. Conclusions European showed phenotypes investigated biomarkers. Especially parental characteristics like hypertension, high maternal BMI, associated unfavorable children.

Language: Английский

Citations

0
Camellia Japonica Radix modulates gut microbiota and 9(S)-HpODE-mediated ferroptosis to alleviate oxidative stress against MASLD DOI
Simin Gu, Chong Chen, Junmin Wang

et al.

Phytomedicine, Journal Year: 2025, Volume and Issue: 143, P. 156806 - 156806

Published: May 6, 2025

Language: Английский

Citations

0
Association between omega-6 fatty acid intake and asthma in US children and adolescents DOI Creative Commons
Xiaolan Zhang, Yangyang Qu,

Linjun Du

et al.

BMC Pediatrics, Journal Year: 2024, Volume and Issue: 24(1)

Published: Oct. 30, 2024

Language: Английский

Citations

0