Advances in the Synthesis of Sulfur-Containing Cyclic Architectures via Insertion of SO2

Synlett, Journal Year: 2024, Volume and Issue: unknown

Published: April 6, 2024

Abstract Sulfur-containing heterocycles, where the S(R) moiety is located within cyclic structure, have found tremendous applications in fields of chemical, pharmaceutical, and materials sciences due to their unique biological pharmaceutical activities. Recent years witnessed increasing interest sulfur-containing new methods for synthesis been reported by adopting modern methodologies technologies through insertion sulfur dioxide. The main objective this Account overview latest major developments on heterocyclic systems, mainly covering thermo-, photo- electron-induced cyclization dioxide (SO2). We aim provide readership with a comprehensive understanding topic offer positive outlook promising future field. 1 Introduction 2 Thermal-Induced Cyclization 3 Photoinduced Radical 4 Electron-Induced 5 Conclusion

Language: Английский

Energy‐transfer Enabled Divergent Synthesis of Polycyclic γ‐Sultines

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: unknown

Published: July 14, 2024

A visible-light-initiated energy-transfer enabled radical cyclization for the divergent synthesis of polycyclic γ-sultine derivatives has been developed. The reaction provides an alternative and expeditious access to benzofused frameworks, analogues γ-lactones γ-sultones, features good functional group compatibility, mild conditions excellent diastereoselectivity. robustness application potential this method have also successfully displayed by two gram-scale reactions sultones. Mechanistic studies indicated transformations through a possible intramolecular homolytic substitution or hydrogen atom transfer process mainly.

Language: Английский