A Borenium-Borane Composite for Exhaustive Reduction of Oxo-Chemicals

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Borenium ions have attracted significant attention in organic transformations due to their strong Lewis acidity. The reported borenium are often stabilized by sterically demanding substituents and coordination bonds. Herein, we synthesized a small steric borenium-equivalent NH3BH2OTf subjected it the exhaustive reduction of carboxylic functional group methyl group, which shows broad tolerance. This system can also undergo reductive deoxygenation reaction alcohols, ethers, other oxo-chemicals (>100 examples). mechanistic studies revealed that situ-generated NH3BH2OTf/[NH3BH2(sol)]OTf, rendering borenium-like properties, plays crucial role these interacting with O atom substrates activate carbonyl facilitating cleavage C–O bond. work has not only offered for but is great significance providing insight into application various reactions.

Language: Английский

Triborane (B₃H₇)-mediated regioselective substitution reactions of pyridine derivatives

Chemical Science, Journal Year: 2024, Volume and Issue: 15(34), P. 13923 - 13929

Published: Jan. 1, 2024

There exists an interplay between borane and a Lewis base in their adducts. However, studies on these adducts so far have mainly focused the different reactions of B-H bonds with limited attention given to influence chemistry base, except for BF

Language: Английский