Risk factors associated with human Mpox infection: a systematic review and meta-analysis
BMJ Global Health,
Journal Year:
2025,
Volume and Issue:
10(2), P. e016937 - e016937
Published: Feb. 1, 2025
Background
Mpox
emerged
as
a
significant
global
public
health
concern
during
the
2022–2023
outbreak,
impacting
populations
in
both
endemic
and
non-endemic
countries.
This
study
reviews
synthesises
evidence
on
risk
factors
associated
with
human
transmission
across
these
regions.
Methods
A
systematic
search
of
peer-reviewed
original
studies
was
conducted
Scopus,
Embase,
Web
Science
PubMed
databases,
covering
publications
up
to
31
March
2024.
The
review
followed
Preferred
Reporting
Items
for
Systematic
Reviews
Meta-Analyses.
Two
authors
independently
screened
articles
by
title,
abstract
full
text.
Newcastle–Ottawa
Scale
used
assess
bias
included
articles.
Fixed-
or
random-effects
meta-analysis
when
at
least
two
reported
ORs
relative
risks,
95%
CIs.
Heterogeneity
assessed
using
I2
statistic.
registered
PROSPERO
(ID:
CRD42023459895
).
Results
identified
947
through
database
searches,
which
met
our
inclusion
criteria.
revealed
infection.
Interaction
infected
animals
(OR=5.61,
CI
2.83,
11.13),
HIV
infection
(OR=4.46,
3.27,
6.08),
other
sexually
transmitted
infections
(OR=1.76,
1.42,
2.19),
unprotected
sexual
activities
(OR=1.53,
1.13,
2.07),
contact
an
person
(OR=2.39,
1.87,
3.05),
identification
men
who
have
sex
(OR=2.18,
1.88,
2.51)
having
multiple
partners
(OR=1.61,
1.24,
2.09)
were
increased
risk.
Conversely,
smallpox
vaccination
significantly
reduced
(OR=0.24,
0.11,
0.55).
Conclusion
Identification
provides
insights
strategic
planning,
enabling
targeted
interventions
high-risk
groups
optimising
resource
allocation
strengthen
control
efforts.
Language: Английский
Risk Factors of Human Mpox (Monkeypox) Infection: A Systematic Review and Meta-Analysis
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 20, 2024
Abstract
Background
Mpox
(formerly
Monkeypox)
virus
has
affected
the
lives
of
thousands
individuals
both
in
endemic
and
non-endemic
countries.
Before
May
2022
outbreak,
infections
were
sporadically
Central
Western
Africa,
still
research
into
been
limited
lacking
epidemiological
data.
Thus,
identification
potential
risk
factors
to
better
understand
who
is
at
being
infected
critical
for
future
prevention
control.
Objective
To
synthesize
comprehensive
evidence
on
associated
with
human
transmission
countries
from
inception
March
31,
2024.
Methods
The
Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses
(PRISMA)
guidelines
followed
conducting
systematic
review.
Electronic
databases
searched.
Two
reviewers
sifted
articles
that
included
review:
firstly,
by
title
abstract,
secondly,
full
text.
We
used
Newcastle-Ottawa
Scale
(NOS)
assess
bias
articles.
Fixed
or
random
effects
meta-analysis
conducted
when
least
two
studies
reported
odds
ratios
(OR),
relative
risks
(RR),
95%
confidence
intervals
(CI).
Heterogeneity
was
assessed
using
I
2
statistic
sensitivity
analysis
also
done.
study
protocol
registered
under
PROSPERO
ID:
CRD42023459895
.
Results
947
identified
database
search
31
eligible
be
findings
showed
interaction
animals
(
OR
=
5.61,
CI
2.83,
11.13),
HIV
4.46,
3.27,
6.08),
other
STIs
1.76,
1.42,
2.91),
sexual
contact/activities
(OR
1.53,
1.13,
4.82),
contact
an
person
2.39,
95%CI
1.87,
3.05),
as
men
have
sex
(MSM)
2.18,
1.88,
2.51),
having
multiple
partners
1.61,
1.24,
2.09),
increased
contracting
Mpox.
However,
patients
vaccinated
against
smallpox
had
a
lower
infection
0.24,
0.11,
0.55).
Conclusion
This
first
Our
demonstrated
certain
Mpox,
whereas
vaccination
protective
role
could
facilitate
strategic
public
health
planning
targeted
intervention.
Key
messages
this
article
What
already
known
topic
(monkeypox)
zoonotic
infectious
disease
notable
global
importance
due
recent
outbreaks
Prior
travel
areas
animals,
close
lesions,
particularly
among
household
members.
adds
add
body
efforts
assist
intervention
revealed
strong
correlation
between
infection,
HVI,
STIs,
physical
contacts,
MSM.
While
may
factor
lesions
STIs.
How
might
affect
research,
practice
policy
results
review
provide
support
policymakers
based
factors.
Language: Английский
Will mpox disease caused by the human Mpox virus (MPXV) result in a pandemic-like situation similar to the COVID-19 pandemic
Venkataramana Kandi
No information about this author
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
21(1)
Published: Oct. 15, 2024
Abstract
The
threat
of
the
emergence
potential
pandemics
in
future
has
been
looming
ever
since
world
witnessed
worst-ever
public
health
catastrophe
following
coronavirus
disease
2019
(COVID-19)
pandemic
caused
by
novel
severe
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2).
COVID-19
affected
billions
people
killing
millions
throughout
world.
Now,
we
have
noticing
an
alarming
rise
cases
mpox
Mpox
virus
(MPXV).
Although
discovered
1958,
was
largely
confined
to
monkeys
before
causing
first
human
infection
1970.
MPXV
is
demonstrating
a
complex
transmission
behavior
as
noted
its
discovery
Denmark
imported
from
Singapore
(Asia)
and
later
spreading
humans
repeated
re-emergence.
African
nations
including
Democratic
Republic
Congo
(DRC)
reemerging
United
States
America
2003
affecting
several
who
had
history
contact
with
animals.
Following
scattered
reports
endemic
regions,
appears
remerged
after
approximately
two
decades
2022
involving
(USA)
European
countries.
across
globe
evidenced
60
countries
more
than
120
current
year.
It
therefore
essential
improve
understanding
MPXV,
epidemiology,
pathogenicity
virulence,
clinical
features,
control
preventive
measures
increase
preparedness
efficiently
tackle
any
emergency.
Language: Английский
How information exposure shape risk perceptions and vaccine intentions of mpox among Gay, Bisexual, and Men Who have Sex with Men in China: A Theory-based Multigroup Analysis (Preprint)
Published: Dec. 28, 2024
BACKGROUND
Exposure
to
information
related
mpox
may
be
different
perceptual
processes
in
relation
vaccination
intent.
OBJECTIVE
This
study
examined
the
specific
pathways
by
which
exposure
and
influence
intent
through
perceived
risk
of
contracting
among
GBMSM
Beijing
Hong
Kong.
METHODS
Data
were
obtained
from
a
cross-sectional
survey
mpox-unvaccinated
Kong
(n=470)
(n=519),
conducted
between
November
2023
March
2024.
Structural
equation
modeling
was
performed
estimate
direct
indirect
effects,
multigroup
structural
used
effect
measure
modification
city.
RESULTS
positive
significantly
enhanced
control
increased
intention
via
higher
for
following
six
months,
particularly
participants
Conversely,
negative
threat
perceptions,
but
did
not
consistently
raise
mpox.
Differences
notable,
with
those
showing
weaker
associations
mpox,
despite
levels
number
non-regular
sex
partners.
CONCLUSIONS
Positive
boosts
increasing
where
programs
are
accessible,
as
Tailored,
stigma-free
communication
is
crucial
improving
uptake,
especially
Mainland
China,
subsidized
vaccines
limited.
Language: Английский
How Information Exposure Shapes Risk Perceptions and Vaccination Intentions Among Gay, Bisexual, and Other Men Who Have Sex with Men in China: A Multigroup Analysis (Preprint)
JMIR Public Health and Surveillance,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 28, 2024
Language: Английский