Individual differences in time-varying and stationary brain connectivity during movie watching from childhood to early adulthood: age, sex, and behavioral associations

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 2, 2023

Spatially remote brain regions exhibit dynamic functional interactions across various task conditions. While time-varying connectivity during movie watching shows sensitivity to content, stationary remains relatively stable videos. These findings suggest that and may represent different aspects of function. However, the relationship between individual differences in behavioral phenotypes elusive. To address this gap, we analyzed an open-access MRI dataset comprising participants aged 5 22 years, who watched two cartoon clips. We calculated regional activity, connectivity, examining associations with age, sex, assessments. Model comparison revealed was more sensitive age sex effects compared connectivity. The preferred models exhibited quadratic log or effects, indicative inverted-U shaped developmental patterns. In addition, females showed higher consistency activity than males. terms predictions, only demonstrated ability predict full-scale intelligence quotient. capture distinct phenotypes.

Language: Английский

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Development of human visual cortical function: A scoping review of task- and naturalistic-fMRI studies through the interactive specialization and maturational frameworks

Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 162, P. 105729 - 105729

Published: May 17, 2024

Overarching theories such as the interactive specialization and maturational frameworks have been proposed to describe human functional brain development. However, these not yet systematically examined across fMRI literature. Visual processing is one of most well-studied fields in neuroimaging, research this area has recently expanded include naturalistic paradigms that facilitate study younger age ranges, allowing for an in-depth critical appraisal childhood. To end, we conducted a scoping review 94 developmental visual studies, including both traditional experimental task multiple sub-domains (early processing, category-specific higher order processing). We found domains, many studies reported progressive development, but few regressive or emergent changes necessary fit frameworks. Our findings suggest need expansion clearer reporting changes, along with well-powered, longitudinal studies.

Language: Английский

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Memory in Infancy and Childhood

Oxford University Press eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1547 - 1575

Published: July 18, 2024

Abstract During the past five decades, there has been a tremendous effort to better understand nature of memory in infancy and early childhood. These findings are beginning address puzzle how it is possible build an impressive semantic during periods development when episodic memories for events unlikely be retained (infantile amnesia, ages 0–2 years) or fragile fragmentary (childhood 2–8 years). This chapter discusses three relevant issues: (a) nontrivial mnemonic capacities infants fit with facts infantile (b) contribution changes key component processes lifting childhood amnesia between 2 8 years, (c) what known about neural underpinnings memory. The highlights importance reciprocal relationship research on theories models mature systems—that is, current knowledge may constrain building viable models, contemporary provide guidance understanding development.

Language: Английский

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Boundaries in the eyes: measure event segmentation during naturalistic video watching using eye tracking

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 23, 2024

During naturalistic information processing, individuals spontaneously segment their continuous experiences into discrete events, a phenomenon known as event segmentation. Traditional methods for assessing this process, which include subjective reports and neuroimaging techniques, often disrupt real-time segmentation or are costly time intensive. Our study investigated the potential of measuring by recording analyzing eye movements while participants view videos. We collected movement data from healthy young adults they watched commercial films (N=104), online Science, Technology, Engineering, Mathematics (STEM) educational courses (N=44). analyzed changes in pupil size speed near boundaries employed inter-subject correlation analysis (ISC) hidden Markov models (HMM) to identify patterns indicative observed that both dynamically responded boundaries, exhibiting heightened sensitivity high-strength boundaries. analyses further revealed synchronized across participants. These can be effectively identified HMM, yielded higher within-event similarity values aligned with human-annotated Importantly, HMM-based metrics experimental manipulations predicted learning outcomes. This provided comprehensive computational framework using eye-tracking. With widespread accessibility low-cost eye-tracking devices, ability measure promises deepen our understanding process diverse real-world settings.

Language: Английский

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Cortical gradients during naturalistic processing are hierarchical and modality-specific

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2022, Volume and Issue: unknown

Published: Oct. 17, 2022

Abstract Understanding cortical topographic organization and how it supports complex perceptual cognitive processes is a fundamental question in neuroscience. Previous work has characterized functional gradients that demonstrate large-scale principles of organization. How these are modulated by rich ecological stimuli remains unknown. Here, we utilize naturalistic via movie-fMRI to assess macroscale We identify principal movie delineate separate hierarchies anchored sensorimotor, visual, auditory/language areas. At the opposite/heteromodal end perception-to-cognition axes, find more central role for frontoparietal network along with default network. Even across different stimuli, demonstrated good reliability, suggesting reflect brain state common conditions. The relative position areas within showed stronger numerous correlations behavioral scores compared resting gradients. Together, findings provide an ecologically valid representation underlying while active engaged multimodal, dynamic processing. Highlights Movie-fMRI reveals novel, granular hierarchical Top three A distinctive third gradient movie-watching regions Gradient reliability even Movie yield behavior

Language: Английский

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