Neuronal activation patterns during self-referential pain imagination DOI Creative Commons
Annabel Vetterlein, Thomas Plieger, Merlin Monzel

et al.

Neurobiology of Pain, Journal Year: 2024, Volume and Issue: 16, P. 100158 - 100158

Published: July 1, 2024

In clinical assessments and pain therapy, patients are asked to imagine themselves in pain. However, the underlying neuronal processes remain poorly understood. Prior research has focused on empathy for or reported small sample sizes. Thus, present study aimed promote neurobiological understanding of self-referential imagination. We hypothesised find activation contrast (pain vs. no pain) across pain-related areas expected two most prominent predictors chronic pain, sensitivity (PS) locus control (LoC), be moderators. an fMRI study, N = 82 participants completed a imagination task, which they were painful non-painful situations presented form pictures texts. After each trial, instructed give painfulness ratings. As laboratory measure PS, electrical thresholds assessed. A questionnaire was LoC. Across presentation modes we found activity contrasts previously regions, such as prefrontal, supplementary motor, primary somatosensory posterior parietal cortices, cerebellum. positive associations PS external LoC with ratings, negative correlation between internal Despite our hypotheses, neither nor significant BOLD-signal contrast. Though future studies needed draw further conclusions, results provide preliminary evidence potential imagination-perception overlap

Language: Английский

Neuronal activation patterns during self-referential pain imagination DOI Creative Commons
Annabel Vetterlein, Thomas Plieger, Merlin Monzel

et al.

Neurobiology of Pain, Journal Year: 2024, Volume and Issue: 16, P. 100158 - 100158

Published: July 1, 2024

In clinical assessments and pain therapy, patients are asked to imagine themselves in pain. However, the underlying neuronal processes remain poorly understood. Prior research has focused on empathy for or reported small sample sizes. Thus, present study aimed promote neurobiological understanding of self-referential imagination. We hypothesised find activation contrast (pain vs. no pain) across pain-related areas expected two most prominent predictors chronic pain, sensitivity (PS) locus control (LoC), be moderators. an fMRI study, N = 82 participants completed a imagination task, which they were painful non-painful situations presented form pictures texts. After each trial, instructed give painfulness ratings. As laboratory measure PS, electrical thresholds assessed. A questionnaire was LoC. Across presentation modes we found activity contrasts previously regions, such as prefrontal, supplementary motor, primary somatosensory posterior parietal cortices, cerebellum. positive associations PS external LoC with ratings, negative correlation between internal Despite our hypotheses, neither nor significant BOLD-signal contrast. Though future studies needed draw further conclusions, results provide preliminary evidence potential imagination-perception overlap

Language: Английский

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