Viruses, Journal Year: 2024, Volume and Issue: 16(10), P. 1521 - 1521
Published: Sept. 26, 2024
Viruses are responsible for many devastating rabbit diseases that impact their health and welfare put conservation economic revenue at risk [...]
Language: Английский
Journal of Veterinary Diagnostic Investigation, Journal Year: 2024, Volume and Issue: 36(5), P. 617 - 637
Published: June 19, 2024
Rabbit hemorrhagic disease virus 2/genotype GI.2 (RHDV2/GI.2; Caliciviridae, Lagovirus) causes a highly contagious with hepatic necrosis and disseminated intravascular coagulation in several Leporidae species. RHDV2 was first detected European rabbits ( Oryctolagus cuniculus) France 2010 has since spread widely. We gather here data on viral detections reported various countries affected species, discuss pathology, genetic differences, novel diagnostic aspects. been almost globally, cases Europe, Africa, Oceania, Asia, North America as of 2023. Since 2020, large scale outbreaks have occurred the United States Mexico and, at same time, for time previously unaffected countries, such China, Japan, Singapore, South among others. Detections notified domestic wild rabbits, hares jackrabbits Lepus spp.), species cottontail brush Sylvilagus pygmy Brachylagus idahoensis), red rock Pronolagus spp.). also few non-lagomorph Detection causing RHD spp. other than those genera is very novel. The global this fast-evolving RNA into unexploited geographic areas increases likelihood host range expansion new are exposed; animals may be infected by nonpathogenic caliciviruses that all which recombination occur.
Language: Английский
Citations
5
Viruses, Journal Year: 2024, Volume and Issue: 16(7), P. 1106 - 1106
Published: July 10, 2024
Rabbit hemorrhagic disease virus 2 (RHDV2) is a highly infectious, often fatal viral that affects both domestic and wild lagomorph species. In the United States (U.S.), first was detected in populations southwest March 2020 has continued to be native North American species over several years. The susceptibility of host exact mechanisms environmental transmission across U.S. landscape remain poorly understood. Our study aims increase understanding RHDV2 by providing history detection. We present summarize results from all RHDV2-suspect morbidity mortality samples submitted for diagnostic testing 2024. Samples were 916 lagomorphs eight 14 western states, which 313 (34.2%) tested positive RT-qPCR. Detections pygmy rabbits (Brachylagus idahoensis) riparian brush (Sylvilagus bachmani riparius) suggest risk threatened endangered warrants more attention. Continuing investigate events tracking detections time can help inform on epidemiology population trends.
Language: Английский
Citations
3
Transboundary and Emerging Diseases, Journal Year: 2023, Volume and Issue: 2023, P. 1 - 9
Published: June 19, 2023
Rabbit haemorrhagic disease virus (RHDV) GI.2 has caused significant declines in the abundance of wild European rabbits (Oryctolagus cuniculus), contributing to species being recently classified as “endangered” its native range. The epidemiology this is still poorly understood despite relevance for domestic and rabbits. During a longitudinal capture-mark-recapture (CMR) study Iberian rabbits, O. c. algirus, semiextensive breeding enclosure, an outbreak RHDV took place January-February 2022, allowing us estimate key epidemiological parameters natural outbreak. From April 2021 July 340 were captured 466 times individually identified, some vaccinated against myxoma (MYXV) and/or GI.2. Sera collected tested IgG specific MYXV GI.2, data analyzed using multievent CMR models. six weeks estimated 81.0% (CI95 77.1–84.3%) population died. Intensive aboveground searches could recover 189 carcasses (50.5% mortality, CI95 41.8–63.4%), with detected 6/7 tested. Apparent seroprevalence rose from 15.4% 8.0–27.5%) January 2022 87.9% 72.7–95.2%) February 2022. apparent mortality GI.2-seropositive during was null, while seronegative it 76.0% 53.8–90.3%). Among higher unvaccinated (100%) than (60.0 ± 16.6%) females males (52.0 17.1%). Infected burrows might explain medium-term persistence following Rabbits antibodies at cutoff seropositivity fully protected fatal infection. Females had fatality rate males, underscoring impact on dynamics endangered species.
Language: Английский
Citations
5
Viruses, Journal Year: 2024, Volume and Issue: 16(6), P. 927 - 927
Published: June 7, 2024
Shah and colleagues [...]
Language: Английский
Citations
1
Viruses, Journal Year: 2024, Volume and Issue: 16(10), P. 1521 - 1521
Published: Sept. 26, 2024
Viruses are responsible for many devastating rabbit diseases that impact their health and welfare put conservation economic revenue at risk [...]
Language: Английский
Citations
0