Advancements in the Detection and Treatment of Rare ALK Fusion Mutations in Hepatocellular Carcinoma: A Case Report and Literature Review DOI Open Access
Quanshu Yan

Qeios, Journal Year: 2024, Volume and Issue: 6(5)

Published: May 25, 2024

This case report and comprehensive literature review highlight the significance of advanced molecular diagnostic techniques, particularly next-generation sequencing (NGS), in identification treatment rare ALK fusion mutations hepatocellular carcinoma (HCC). Through a detailed analysis single patient case, accompanied by existing literature, we underscore challenges therapeutic potential associated with fusions HCC. Our findings demonstrate superior capability NGS, both DNA-based RNA-based, detecting these mutations, leading to targeted approaches inhibitors. The illustrates practical application precision oncology HCC, showcasing significant clinical benefit improved outcomes use inhibitors for types. study not only contributes body knowledge documenting instance HCC but also advocates integration profiling into standard practice enhance personalized strategies care.

Language: Английский

Assessment and Improvement of Nutritional Knowledge among Hospitalized Cancer Patients: Gaps, Sources, and Educational Strategies DOI Open Access

Qiu Yan

Qeios, Journal Year: 2024, Volume and Issue: unknown

Published: March 18, 2024

This study explores the nutritional knowledge, its acquisition, and assessment among hospitalized cancer patients, revealing significant gaps influence of demographic factors. The research identifies predominance informal unreliable sources for information, such as internet searches peer advice, highlighting inadequacy in patient education provided by healthcare professionals. Additionally, addresses lack validated tools evaluating patients' emphasizing need comprehensive accessible educational resources standardized measurement instruments. findings advocate an integrated approach involving personalized guidance development to improve knowledge health outcomes.

Language: Английский

Citations

0

Strategies for Management and Long-term Surveillance of Pediatric Differentiated Thyroid Cancer: Balancing Efficacy and Quality of Life DOI Open Access

Dahuang Tao

Qeios, Journal Year: 2024, Volume and Issue: unknown

Published: March 18, 2024

Pediatric differentiated thyroid cancer (DTC) presents unique challenges distinct from its adult counterparts, including higher rates of multifocality, regional lymph node involvement, and distant metastases. This article reviews the latest advancements controversies in surgical management, postoperative care, long-term surveillance pediatric DTC, emphasizing importance a tailored approach based on individual risk assessments. The evolving landscape treatment strategies aims to balance imperative effective control with need mitigate adverse effects ensure quality life. review also highlights critical for ongoing research multidisciplinary collaboration refine optimize management protocols this vulnerable population.

Language: Английский

Citations

0

Challenges and Opportunities in Mobile Health Technologies for Cancer Pain Management: An Integrative Review DOI Open Access

Dahuang Tao

Qeios, Journal Year: 2024, Volume and Issue: unknown

Published: March 18, 2024

This article explores the evolving landscape of mobile cancer pain management, a critical aspect healthcare innovation aimed at enhancing patient outcomes and accessibility to relief measures. Through comprehensive analysis, study examines benefits, limitations, potential strategies for overcoming challenges associated with implementing health technologies in management cancer-related pain. The discussion includes an evaluation effectiveness, adherence, technological advancements health, alongside assessment barriers hindering widespread adoption, such as cultural literacy, resource allocation, security concerns.

Language: Английский

Citations

0

Strategies for Management and Long-term Surveillance of Pediatric Differentiated Thyroid Cancer: Balancing Efficacy and Quality of Life DOI Open Access

Dahuang Tao

Qeios, Journal Year: 2024, Volume and Issue: 6(4)

Published: April 23, 2024

Pediatric differentiated thyroid cancer (DTC) presents unique challenges distinct from its adult counterparts, including higher rates of multifocality, regional lymph node involvement, and distant metastases. This article reviews the latest advancements controversies in surgical management, postoperative care, long-term surveillance pediatric DTC, emphasizing importance a tailored approach based on individual risk assessments. The evolving landscape treatment strategies aims to balance imperative effective control with need mitigate adverse effects ensure quality life. review also highlights critical for ongoing research multidisciplinary collaboration refine optimize management protocols this vulnerable population.

Language: Английский

Citations

0

The Application and Pathway Regulation of Traditional Chinese Medicine in Lung Cancer Treatment: An Exploratory Review DOI Open Access

Jinghan Huang

Qeios, Journal Year: 2024, Volume and Issue: 6(5)

Published: May 30, 2024

Lung cancer is one of the cancers with highest mortality rates. Non-small cell lung (NSCLC) accounts for 85% cases and often diagnosed at an advanced stage a poor prognosis. Due to lack effective molecular targets, current clinical cure rate low, recurrence high. Recent studies have found that active components traditional Chinese medicine herbal formulas can inhibit development NSCLC through multiple pathways effectively reducing its metastasis rates, improving treatment side effects, compensating deficiencies in drug resistance. Although treatments such as surgery, radiotherapy, targeted therapy, immunotherapy achieved better efficacy treating cancer, they still problems complications severe adverse reactions. In recent years, numerous basic confirmed good effects cancer. Traditional has synergistic regulatory effect components, pathways, channels. The monomeric complex mechanisms action determine there are issues unclear related prevention by medicine. There urgent need elucidate intervening from perspective modern medicine, levels biology, network pharmacology, etc. This article systematically summarizes research progress on regulation above-mentioned signaling expression key protein molecules monomers or formulas, aiming clarify progression provide ideas theoretical basis in-depth study application

Language: Английский

Citations

0

Advancements in the Detection and Treatment of Rare ALK Fusion Mutations in Hepatocellular Carcinoma: A Case Report and Literature Review DOI Open Access
Quanshu Yan

Qeios, Journal Year: 2024, Volume and Issue: 6(5)

Published: May 25, 2024

This case report and comprehensive literature review highlight the significance of advanced molecular diagnostic techniques, particularly next-generation sequencing (NGS), in identification treatment rare ALK fusion mutations hepatocellular carcinoma (HCC). Through a detailed analysis single patient case, accompanied by existing literature, we underscore challenges therapeutic potential associated with fusions HCC. Our findings demonstrate superior capability NGS, both DNA-based RNA-based, detecting these mutations, leading to targeted approaches inhibitors. The illustrates practical application precision oncology HCC, showcasing significant clinical benefit improved outcomes use inhibitors for types. study not only contributes body knowledge documenting instance HCC but also advocates integration profiling into standard practice enhance personalized strategies care.

Language: Английский

Citations

0