This
case
report
and
comprehensive
literature
review
highlight
the
significance
of
advanced
molecular
diagnostic
techniques,
particularly
next-generation
sequencing
(NGS),
in
identification
treatment
rare
ALK
fusion
mutations
hepatocellular
carcinoma
(HCC).
Through
a
detailed
analysis
single
patient
case,
accompanied
by
existing
literature,
we
underscore
challenges
therapeutic
potential
associated
with
fusions
HCC.
Our
findings
demonstrate
superior
capability
NGS,
both
DNA-based
RNA-based,
detecting
these
mutations,
leading
to
targeted
approaches
inhibitors.
The
illustrates
practical
application
precision
oncology
HCC,
showcasing
significant
clinical
benefit
improved
outcomes
use
inhibitors
for
types.
study
not
only
contributes
body
knowledge
documenting
instance
HCC
but
also
advocates
integration
profiling
into
standard
practice
enhance
personalized
strategies
care.
Qeios,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 18, 2024
This
study
explores
the
nutritional
knowledge,
its
acquisition,
and
assessment
among
hospitalized
cancer
patients,
revealing
significant
gaps
influence
of
demographic
factors.
The
research
identifies
predominance
informal
unreliable
sources
for
information,
such
as
internet
searches
peer
advice,
highlighting
inadequacy
in
patient
education
provided
by
healthcare
professionals.
Additionally,
addresses
lack
validated
tools
evaluating
patients'
emphasizing
need
comprehensive
accessible
educational
resources
standardized
measurement
instruments.
findings
advocate
an
integrated
approach
involving
personalized
guidance
development
to
improve
knowledge
health
outcomes.
Qeios,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 18, 2024
Pediatric
differentiated
thyroid
cancer
(DTC)
presents
unique
challenges
distinct
from
its
adult
counterparts,
including
higher
rates
of
multifocality,
regional
lymph
node
involvement,
and
distant
metastases.
This
article
reviews
the
latest
advancements
controversies
in
surgical
management,
postoperative
care,
long-term
surveillance
pediatric
DTC,
emphasizing
importance
a
tailored
approach
based
on
individual
risk
assessments.
The
evolving
landscape
treatment
strategies
aims
to
balance
imperative
effective
control
with
need
mitigate
adverse
effects
ensure
quality
life.
review
also
highlights
critical
for
ongoing
research
multidisciplinary
collaboration
refine
optimize
management
protocols
this
vulnerable
population.
Qeios,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 18, 2024
This
article
explores
the
evolving
landscape
of
mobile
cancer
pain
management,
a
critical
aspect
healthcare
innovation
aimed
at
enhancing
patient
outcomes
and
accessibility
to
relief
measures.
Through
comprehensive
analysis,
study
examines
benefits,
limitations,
potential
strategies
for
overcoming
challenges
associated
with
implementing
health
technologies
in
management
cancer-related
pain.
The
discussion
includes
an
evaluation
effectiveness,
adherence,
technological
advancements
health,
alongside
assessment
barriers
hindering
widespread
adoption,
such
as
cultural
literacy,
resource
allocation,
security
concerns.
Pediatric
differentiated
thyroid
cancer
(DTC)
presents
unique
challenges
distinct
from
its
adult
counterparts,
including
higher
rates
of
multifocality,
regional
lymph
node
involvement,
and
distant
metastases.
This
article
reviews
the
latest
advancements
controversies
in
surgical
management,
postoperative
care,
long-term
surveillance
pediatric
DTC,
emphasizing
importance
a
tailored
approach
based
on
individual
risk
assessments.
The
evolving
landscape
treatment
strategies
aims
to
balance
imperative
effective
control
with
need
mitigate
adverse
effects
ensure
quality
life.
review
also
highlights
critical
for
ongoing
research
multidisciplinary
collaboration
refine
optimize
management
protocols
this
vulnerable
population.
Lung
cancer
is
one
of
the
cancers
with
highest
mortality
rates.
Non-small
cell
lung
(NSCLC)
accounts
for
85%
cases
and
often
diagnosed
at
an
advanced
stage
a
poor
prognosis.
Due
to
lack
effective
molecular
targets,
current
clinical
cure
rate
low,
recurrence
high.
Recent
studies
have
found
that
active
components
traditional
Chinese
medicine
herbal
formulas
can
inhibit
development
NSCLC
through
multiple
pathways
effectively
reducing
its
metastasis
rates,
improving
treatment
side
effects,
compensating
deficiencies
in
drug
resistance.
Although
treatments
such
as
surgery,
radiotherapy,
targeted
therapy,
immunotherapy
achieved
better
efficacy
treating
cancer,
they
still
problems
complications
severe
adverse
reactions.
In
recent
years,
numerous
basic
confirmed
good
effects
cancer.
Traditional
has
synergistic
regulatory
effect
components,
pathways,
channels.
The
monomeric
complex
mechanisms
action
determine
there
are
issues
unclear
related
prevention
by
medicine.
There
urgent
need
elucidate
intervening
from
perspective
modern
medicine,
levels
biology,
network
pharmacology,
etc.
This
article
systematically
summarizes
research
progress
on
regulation
above-mentioned
signaling
expression
key
protein
molecules
monomers
or
formulas,
aiming
clarify
progression
provide
ideas
theoretical
basis
in-depth
study
application
This
case
report
and
comprehensive
literature
review
highlight
the
significance
of
advanced
molecular
diagnostic
techniques,
particularly
next-generation
sequencing
(NGS),
in
identification
treatment
rare
ALK
fusion
mutations
hepatocellular
carcinoma
(HCC).
Through
a
detailed
analysis
single
patient
case,
accompanied
by
existing
literature,
we
underscore
challenges
therapeutic
potential
associated
with
fusions
HCC.
Our
findings
demonstrate
superior
capability
NGS,
both
DNA-based
RNA-based,
detecting
these
mutations,
leading
to
targeted
approaches
inhibitors.
The
illustrates
practical
application
precision
oncology
HCC,
showcasing
significant
clinical
benefit
improved
outcomes
use
inhibitors
for
types.
study
not
only
contributes
body
knowledge
documenting
instance
HCC
but
also
advocates
integration
profiling
into
standard
practice
enhance
personalized
strategies
care.