Neochloris aquatica induces larval mortality, molting defects, and unstable flightless adults in the Asian tiger mosquito DOI
María Florencia Gil, María Florencia Tano de la Hoz, Marisol Fassolari

et al.

Journal of Invertebrate Pathology, Journal Year: 2023, Volume and Issue: 202, P. 108041 - 108041

Published: Dec. 11, 2023

Language: Английский

Valorization of Bioactive Metabolites from Trichodesmium erythraeum Bloom Biomass for Vector Borne Disease Control, Bactericidal and Anticancer Therapy DOI
Parthasarathy Surya, Seema Siddharthan, Saleh H. Salmen

et al.

Waste and Biomass Valorization, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

Language: Английский

Citations

0
An oral toxicity assessment of a mosquito larvicidal transgenic algae (Chlamydomonas reinhardtii) using adult Zebrafish and its embryos DOI Creative Commons
Fareeha Amjad, Hamza Khan,

Muhammad Islam Khan

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(6), P. e0303352 - e0303352

Published: June 13, 2024

Mosquito-borne diseases pose a global health threat, with pathogens like Malaria, Dengue fever, and others transmitted by mosquitoes. Our study focuses on evaluating the toxicity of genetically engineered mosquito larvicidal algae ( Chlamydomonas reinhardtii ) to non-target organisms, specifically Zebrafish. We conducted 90-day experiment, feeding Zebrafish different combinations commercial fish feed. Statistical analysis revealed no significant differences in mortality, allergenicity, or moribundity among groups. Hematology, molecular analysis, necropsy showed physiological differences. findings indicate that transgenic (TN72.cry11Ba) had adverse effects adult their larvae. This confirmed safety such as zebrafish.

Language: Английский

Citations

0
Valorization of bioactive metabolites from Trichodesmium erythraeum bloom biomass for vector borne disease control, bactericidal and anticancer therapy DOI Creative Commons
Parthasarathy Surya, Seema Siddharthan, Saleh H. Salmen

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 9, 2024

Abstract In the marine environment, algae are regarded as globally distributed entity. The excessive accumulation of nutrients such nitrogen or phosphorus causes an algal bloom, which is caused by rapid growth microscopic rather than macroscopic ones. Even though it has negative effects, its significance in terms biological usage was limited to experimental perspective. our study, we have utilized waste biomass Trichodesmium erythraeum valorize natural metabolites for vector control, bacterial inhibition and anticancer study. Among solvents, methanolic extract produced significant mosquitocidal action against A. stephensi, aegypti, C. quinquefasciatus. T. were found inhibit clinical pathogens including B. subtilis, P. mirabilis, S. aureus, E. coli K. pneumoniae. Further, methanol mediated effect assessed on non-small cell lung cancer lines. Moreover, displayed no impact non-target organism. FT-IR results suggested incidence alkanes (–C ≡ C–H: C–H stretch), nitrile (C N), (primary amines (N–H bend), aliphatic (C–N alkenes (= bend) nitro compounds (N–O asymmetric stretch). GCMS analysis listed series Hexadecanoic acid, Bicyclo [10.1.0] tridec-1-ene, Glycidol stearate, Tricyclo [20.8.0.0 (7, 16)] triacontane, 1(22), 7 (16)-diepoxy- Piperidine played vital role control bactericidal action. This study specifies obtained imply that might be useful essential medicinal applications.

Language: Английский

Citations

0
Toxicity of Macroalgae Extracts to Larvae of the Northern House Mosquito DOI Creative Commons
Ahmed Ali Rashed, Yasmin M. Heikal, ROBERT FINN

et al.

Life, Journal Year: 2024, Volume and Issue: 14(12), P. 1527 - 1527

Published: Nov. 21, 2024

The continuous use of synthetic insecticides to suppress mosquito larvae has detrimental impacts on the environment and human health. Finding novel target-specific bio-insecticides become crucial. Here, larvicidal genotoxic activities different extracts from Ulva lactuca Turbinaria ornata toward Culex pipiens were investigated. macroalgae thalli subjected various solvent extractions followed by phytochemical quantification, testing C. larvae, evaluation through comet assays, compound characterization gas chromatography–mass spectrometry. methylene chloride extract U. displayed highest toxicity with LC50 = 30.99 ppm, acetone T. ornata, 52.09 ppm after 72 h. exhibited maximum contents total alkaloids, flavonoids, terpenoids, phenols, tannins methanol extract, while phenols. caused significant DNA damage in larva body cells. Thus, showed promising potential as environmentally friendly larvicides against larvae.

Language: Английский

Citations

0
Neochloris aquatica induces larval mortality, molting defects, and unstable flightless adults in the Asian tiger mosquito DOI
María Florencia Gil, María Florencia Tano de la Hoz, Marisol Fassolari

et al.

Journal of Invertebrate Pathology, Journal Year: 2023, Volume and Issue: 202, P. 108041 - 108041

Published: Dec. 11, 2023

Language: Английский

Citations

0