Novel phytosterol with Antimicrobial Potential of Digera muricata Mart. from Chittorgarh Region, India DOI Creative Commons
Nalini Tomer, Anil Kumar Sharma, Mohammad Irfan Ali

et al.

Journal of Pure and Applied Microbiology, Journal Year: 2024, Volume and Issue: 18(3), P. 1648 - 1660

Published: July 22, 2024

Digera muricata Mart, a plant having therapeutic characteristics that has been utilised traditionally, belongs to the Amaranthaceae family, and promising source of specific natural products utilized as antioxidant, prophylactic, antimicrobial, anthelmintic, anti-diabetic, allelopathic agent. In present study, biologically active phytosterol was isolated from Mart. The compound characterized by 13C, 1H NMR, FTIR, HRMS. Characterization isolate done antimicrobial assay, molecular docking. potential (50 µl) against Streptococcus pyogenes found be maximum (ZOI-20.0 ± 1.0), followed agalactiae (ZOI-11.3±1.5), Candida albicans (ZOI- 09.0 Klebsiella pneumonia (ZOI-8.6 1.5) Escherichia coli 1.5). docking results indicate binds receptor 1AI9 at 32th 58th positions; 1KZN 76th position, 5L3J 46th (ASN) 136th (ARG) position; 7WIJ 419th 582th (ASP) 585th positions.

Language: Английский

Botanical specifications, ethnobotany, phytochemistry, and pharmacology of herb Digera muricata (L.) Mart: a systematic review DOI
Priyanka Sharma, Sakshi Saini, Jyoti Sharma

et al.

Phytochemistry Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Language: Английский

Citations

0
Evaluating the Anticancer Properties of Musa acuminata colla Ethanolic Extract through In vitro Analysis DOI Creative Commons
Anu Augustine, Geethalakshmi Sundararaman,

Prem Jose Vazhacharical

et al.

UTTAR PRADESH JOURNAL OF ZOOLOGY, Journal Year: 2024, Volume and Issue: 45(12), P. 231 - 240

Published: May 28, 2024

The study examined the possible anticancer properties of a colla pulp extract derived from Musa acuminata. It employed three different cancer cell lines, MDA-MB-231 (breast cancer), HCT-116 (colon and MG-63 (osteosarcoma). We evaluated antiproliferative using MTT test identified bioactive components through GC-MS analysis. analysis showed that ethanol contained several compounds could be useful in fight against cancer. These included palmitic acid, linoleic 5-hydroxymethylfurfural, 5-Methyl-2-ethylamino-2-thiazoline. remarkable cytotoxicity with IC50 values 250 µg/ml, 175 320 µg/ml for MDA-MB-231, HCT-116, respectively. Finally, it was determined banana contains significant number phenolic compounds, provitamin A, antioxidants. present suggests bananas have promising uses field research, treatment, prevention.

Language: Английский

Citations

0
Novel phytosterol with Antimicrobial Potential of Digera muricata Mart. from Chittorgarh Region, India DOI Creative Commons
Nalini Tomer, Anil Kumar Sharma, Mohammad Irfan Ali

et al.

Journal of Pure and Applied Microbiology, Journal Year: 2024, Volume and Issue: 18(3), P. 1648 - 1660

Published: July 22, 2024

Digera muricata Mart, a plant having therapeutic characteristics that has been utilised traditionally, belongs to the Amaranthaceae family, and promising source of specific natural products utilized as antioxidant, prophylactic, antimicrobial, anthelmintic, anti-diabetic, allelopathic agent. In present study, biologically active phytosterol was isolated from Mart. The compound characterized by 13C, 1H NMR, FTIR, HRMS. Characterization isolate done antimicrobial assay, molecular docking. potential (50 µl) against Streptococcus pyogenes found be maximum (ZOI-20.0 ± 1.0), followed agalactiae (ZOI-11.3±1.5), Candida albicans (ZOI- 09.0 Klebsiella pneumonia (ZOI-8.6 1.5) Escherichia coli 1.5). docking results indicate binds receptor 1AI9 at 32th 58th positions; 1KZN 76th position, 5L3J 46th (ASN) 136th (ARG) position; 7WIJ 419th 582th (ASP) 585th positions.

Language: Английский

Citations

0