Neuropsychiatric Burden of SARS-CoV-2: A Review of Its Physiopathology, Underlying Mechanisms, and Management Strategies DOI Creative Commons

Aliteia-Maria Pacnejer,

Anca Butucă, Carmen Maximiliana Dobrea

et al.

Viruses, Journal Year: 2024, Volume and Issue: 16(12), P. 1811 - 1811

Published: Nov. 21, 2024

The COVID-19 outbreak, caused by the SARS-CoV-2 virus, was linked to significant neurological and psychiatric manifestations. This review examines physiopathological mechanisms underlying these neuropsychiatric outcomes discusses current management strategies. Primarily a respiratory disease, frequently leads issues, including cephalalgia migraines, loss of sensory perception, cerebrovascular accidents, impairment such as encephalopathy. Lasting neuropsychological effects have also been recorded in individuals following infection. These include anxiety, depression, cognitive dysfunction, suggesting lasting impact on mental health. neuroinvasive potential inflammatory responses, role angiotensin-converting enzyme 2 (ACE2) neuroinflammation are critical factors In addition, highlights importance monitoring biomarkers assess Central Nervous System (CNS) involvement. Management strategies for conditions supportive therapy, antiepileptic drugs, antithrombotic psychotropic emphasizing need multidisciplinary approach. Understanding long-term implications is essential developing effective treatment protocols improving patient outcomes.

Language: Английский

Neuropsychiatric Burden of SARS-CoV-2: A Review of Its Physiopathology, Underlying Mechanisms, and Management Strategies DOI Creative Commons

Aliteia-Maria Pacnejer,

Anca Butucă, Carmen Maximiliana Dobrea

et al.

Viruses, Journal Year: 2024, Volume and Issue: 16(12), P. 1811 - 1811

Published: Nov. 21, 2024

The COVID-19 outbreak, caused by the SARS-CoV-2 virus, was linked to significant neurological and psychiatric manifestations. This review examines physiopathological mechanisms underlying these neuropsychiatric outcomes discusses current management strategies. Primarily a respiratory disease, frequently leads issues, including cephalalgia migraines, loss of sensory perception, cerebrovascular accidents, impairment such as encephalopathy. Lasting neuropsychological effects have also been recorded in individuals following infection. These include anxiety, depression, cognitive dysfunction, suggesting lasting impact on mental health. neuroinvasive potential inflammatory responses, role angiotensin-converting enzyme 2 (ACE2) neuroinflammation are critical factors In addition, highlights importance monitoring biomarkers assess Central Nervous System (CNS) involvement. Management strategies for conditions supportive therapy, antiepileptic drugs, antithrombotic psychotropic emphasizing need multidisciplinary approach. Understanding long-term implications is essential developing effective treatment protocols improving patient outcomes.

Language: Английский

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