The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study

Diseases, Journal Year: 2025, Volume and Issue: 13(3), P. 77 - 77

Published: March 7, 2025

Healthcare workers (HCWs) are frequently exposed to a variety of chemical agents, which can result in the development allergic or irritant contact dermatitis. The present study aimed assess prevalence skin sensitization among HCWs who presented with symptoms dermatitis, considering both occupational and non-occupational risk factors. population comprised 127 attended routine health surveillance at Tor Vergata Teaching Hospital Rome between November 2023 May 2024. A structured dermatitis questionnaire patch testing were administered participants. Demographic lifestyle data, including information on occupation, night shift work, smoking habits, body mass index (BMI), collected. Patch test positivity was observed 31.5% participants, most common clinical presentation being erythematous-desquamative significantly higher likelihood nurses (57.1%), particularly for nickel sensitization, compared other groups. trend towards an association work observed, although this did not reach statistical significance. No significant associations found ages over 35 years, sex, BMI. These findings highlight elevated nurses, emphasizing need targeted interventions, exposure reduction strategies protective measures, mitigate hazards healthcare settings.

Language: Английский

Efficacy and Safety Assessment of Topical Omega Fatty Acid Product in Experimental Model of Irritant Contact Dermatitis: Randomized Controlled Trial

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(15), P. 6423 - 6423

Published: July 23, 2024

Contact dermatitis is a common inflammatory skin disease that often requires prescription therapy and associated with adverse reactions. Omega fatty acids have been recognized for their anti-inflammatory effect could serve as safer option in contact treatment. Therefore, the aim of this randomized controlled study, conducted at University Split School Medicine, was to evaluate efficacy safety omega containing topical products an experimental model irritant dermatitis. This study registered ClinicalTrials (NCT06189144) closed. The primary outcomes were levels transepidermal water loss, hydration, erythema, all measured using MPA6 device 25 healthy participants. A significant difference observed between hydration values intervention (45.7 ± 12.4) control groups (31.6 12.3) (p < 0.05) on final measurements (day 10). Moreover, higher erythema participants who smokers, compared non-smokers. No drug reactions during period. In conclusion, product use shows promise treatment dermatitis, further studies are needed larger sample patients.

Language: Английский

Assessment of Hypersensitivity to House Dust Mites in Selected Skin Diseases Using the Basophil Activation Test: A Preliminary Study

Medicina, Journal Year: 2024, Volume and Issue: 60(10), P. 1608 - 1608

Published: Oct. 1, 2024

: Allergy to dust mites (HDMs) plays an important role in atopic dermatitis (AD). However, the of this allergy other dermatoses is little known. The aim study was assess hypersensitivity HDMs patients with AD or hand disease using basophil activation test.

Language: Английский