SARS-CoV-2 infection and complicated appendicitis in adults in Lima, Peru: a matched case-control study

BMC Surgery, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 16, 2025

Language: Английский

Acute Pancreatitis Induced by COVID-19 Vaccine: A Systematic Review

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: March 3, 2024

Acute pancreatitis, marked by sudden inflammation of the pancreas, presents a complex spectrum causative factors including gallstone obstruction, alcohol abuse, and viral infections. Recent studies have illuminated emergence vaccine-induced acute notably associated with COVID-19 vaccinations, presenting diverse mechanisms ranging from direct viral-mediated injury to autoimmune reactions. Understanding this link is pivotal for public health, yet challenges persist in identifying managing cases post-vaccination. Comprehensive literature reviews employing PRISMA (Preferred Reporting Items Systematic Reviews Meta-Analyses) statement outline potential pathways leading emphasizing need deeper investigations into underlying health conditions modifications vaccine components. Notably, rare occurrences pancreatitis extend beyond vaccines, reports also documenting associations measles, mumps, rubella (MMR), human papillomavirus (HPV), other vaccinations. Mechanistically, hypotheses such as molecular mimicry immunologic been proposed, necessitating ongoing vigilance exploration. Regulatory agencies play crucial role monitoring communicating safety concerns, transparency address risks maintain trust. these adverse events remain integral informed vaccination policies allay concerns surrounding safety.

Language: Английский

Exploring Acute Pancreatitis in Kidney Transplant Recipients: A Multicentre Retrospective Cohort Analysis of Incidence, Causes, and Clinical Outcomes

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(12), P. 3366 - 3366

Published: June 7, 2024

Background: The aim of this multicentre retrospective study is to determine the incidence, etiology, clinical characteristics, and outcomes kidney transplant recipients diagnosed treated for acute pancreatitis. Methods: We analyzed data from who received allografts between October 1973 December 2023 were Results: Of 2482 patients allografts, 10 (0.4%) (5 male) with pancreatitis, a mean age 48.6 years. Patients pancreatitis 3 weeks 24 years after transplantation. Possible etiologies included cholecystolithiasis, COVID-19, hypercalcemia, postprocedural, use cannabis, trimetoprim-sulphometoxasole, statins, sirolimus, tacrolimus obesity. There was no suspected etiology in two patients. aggressive hydration, pain alleviation antibiotics if indicated. Four developed complications. Local complications peripancreatic collections, pseudocyst, abscesses formation, while systemic occurred form Cytomegalovirus (CMV) reactivation urinary tract infection. All survived preserved allograft function. Conclusions: Acute rare. However, it may be linked significant morbidity mortality. While symptoms nonspecific brought on by variety viral non-infectious illnesses, as well adverse effects immunosuppressive medications, high degree awareness required.

Language: Английский