Supramolecular Assemblies with Aggregation-Induced Emission for in Situ Active Imaging-Guided Photodynamic Therapy of Cancer Cells DOI
Yu Xiang,

Zongze Duan,

Hai Yang

и другие.

Опубликована: Янв. 1, 2024

Язык: Английский

Biomedical applications of NIR-II organic small molecule fluorescent probes in different organs DOI
Lizhen Xu, Qian Zhang, Xin Wang

и другие.

Coordination Chemistry Reviews, Год журнала: 2024, Номер 519, С. 216122 - 216122

Опубликована: Авг. 6, 2024

Язык: Английский

Процитировано

15
Phototherapy: progress, challenges, and opportunities DOI
Xi Yuan,

Junliang Zhou,

Lin Yuan

и другие.

Science China Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 5, 2024

Язык: Английский

Процитировано

8
DNA tetrahedron nanomedicine for enhanced antitumor and antimetastatic effect through the amplification of mitochondrial oxidative stress DOI
Zixuan Chen,

Zhaoyan Tian,

Yafeng Wu

и другие.

Acta Biomaterialia, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Exceptional Near-Infrared II Organic Small Molecule Nanoagent for Photoacoustic/Photothermal Imaging-Guided Highly Efficient Therapy in Cancer DOI

Yidong Bin,

Lixian Huang,

Jiang‐Ke Qin

и другие.

Bioconjugate Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 12, 2025

Near-infrared II (NIR-II) photoacoustic (PA)/photothermal imaging-guided tumor therapy holds great promise in precision medicine for cancer treatment. This work reports on the synthesis and application of an organic small molecule nanoagent that has exceptional PA photothermal properties near-infrared region. BCy-TPE was constructed by linking NIR-II absorbing cyanine dye BCy-Cl with a twisted tetraphenylethene unit. The synthesized exhibited intense absorption peak at 1032 nm. After encapsulation into water-dispersible nanoparticles (NPs), NPs two peaks 880 1046 Notably, under 1064 nm laser excitation, deliver remarkable conversion efficiency 92%, together superior biocompatibility, photostability, PA/photothermal imaging capability. Moreover, after intravenous administration 4T1 tumor-bearing mice treatment safe-intensity (1.0 W cm-2 nm) irradiation, temperature increased rapidly to 52 °C within 1 min tumors are completely ablated single Overall, this offers novel strategy develop superb agents highly efficient cancer.

Язык: Английский

Процитировано

0
A Spiro‐Based NIR‐II Photosensitizer with Efficient ROS Generation and Thermal Conversion Performances for Imaging‐Guided Tumor Theranostics DOI Open Access

Y. W. Jin,

Kang Xu, Baoyi Ren

и другие.

Advanced Healthcare Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Abstract Organic photosensitizers (PSs) possessing NIR‐II emission and photodynamic/photothermal effect have received a great sense of attention for their cutting‐edge applications in imaging‐guided multimodal phototherapy. However, it is highly challenging to design efficient PSs with high luminescence phototherapy performance simultaneously. In this study, spiro‐functionalization strategy proposed alleviate aggregate‐caused quenching promote photodynamic therapy, the verified via spiro[fluorine‐9,9ʹ‐xanthene]‐modified PS (named SFX‐IC) an acceptor–donor–acceptor configuration. SFX‐IC‐based nanoparticles (NPs) display molar extinction coefficient 7.05 × 10 4 m ‒1 cm −1 at 645 nm due strong intramolecular charge‐transfer characteristics. As expected, as‐prepared NPs show fluorescence quantum yield 1.1%, thanks spiro‐configuration that suppressing excessively intermolecular π–π stacking. Furthermore, SFX‐IC not only efficiently generate 1 O 2 ∙− under 660 laser irradiation, but also possess good photothermal conversion efficiency 47.14%. Consequently, can be served as versatile phototheranostic agents fluorescence/photoacoustic phototherapy, manifesting spiro‐functionalized powerful tool construct emitting PSs.

Язык: Английский

Процитировано

0
Recent advances in nanomaterials for integrated phototherapy and immunotherapy DOI Creative Commons
Zhuqing Sun, Nannan Wang, Yelin Wu

и другие.

Coordination Chemistry Reviews, Год журнала: 2025, Номер 535, С. 216608 - 216608

Опубликована: Март 27, 2025

Язык: Английский

Процитировано

0
Regulated cell death mechanisms in mitochondria-targeted phototherapy DOI
Qihang Ding, Hyeonji Rha,

Changyu Yoon

и другие.

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113720 - 113720

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Redox-responsive self-assembled peptide hydrogel for mitochondrial-targeted anticancer drug delivery DOI
Leixia Mei,

Qing Mei,

Weimiao Dong

и другие.

Applied Materials Today, Год журнала: 2024, Номер 41, С. 102471 - 102471

Опубликована: Окт. 13, 2024

Язык: Английский

Процитировано

2
ATP-Responsive ZIF-based NIR Fluorescent Nanosystem for Enhanced Chemo-Photodynamic Therapy of Tumors DOI
Sisi Chen,

Xiao-Fan Xu,

Wei-Qun Deng

и другие.

Nanoscale, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

An ATP-responsive fluorescence nanosystem for chemo-photodynamic therapy is reported. The can avoid premature drug leakage and enhance local delivery.

Язык: Английский

Процитировано

1
Supramolecular assemblies with aggregation-induced emission for in situ active imaging-guided photodynamic therapy of cancer cells DOI
Yu Xiang,

Zongze Duan,

Hai Yang

и другие.

Talanta, Год журнала: 2024, Номер 280, С. 126722 - 126722

Опубликована: Авг. 22, 2024

Язык: Английский

Процитировано

0