Materials Horizons, Год журнала: 2024, Номер 11(22), С. 5564 - 5577
Опубликована: Янв. 1, 2024
We report the preparation of a small library copper-based metallenes, such as copperene, brassene, bronzene, cupronickelene and AlCuZn trimetallene,
Язык: Английский
Discover Materials, Год журнала: 2025, Номер 5(1)
Опубликована: Янв. 9, 2025
Achieving the ideal replacement for robust biological tissues requires biocompatible materials with a nuanced blend of characteristics, including organ specific toughness, durability, self-repairing capability, and well-defined structure. Hydrogels, structured high water containing 3D-crosslinked polymeric networks, present promising avenue in biomedical applications due to their close resemblance natural tissues. However, mechanical performance often falls short, limiting clinical applications. Recent research has been focused on developing hydrogel therapeutic advancements have spurred researchers develop hydrogels having acceptable toughness. While it is now possible tailor properties synthetic gels mimic those tissues, critical aspects such as biocompatibility crosslinking strategies are frequently neglected. This review scrutinizes structural techniques designed improve toughness hydrogels, focusing especially innovative efforts integrate these enhancements into natural-based hydrogels. By thoroughly examining methodologies, sheds light complexities strengthening will propose valuable insights development next-generation tissue substitutes.
Язык: Английский
Процитировано
7
Chemical Engineering Journal, Год журнала: 2024, Номер 495, С. 153314 - 153314
Опубликована: Июнь 19, 2024
Язык: Английский
Процитировано
12
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 271, С. 132357 - 132357
Опубликована: Май 19, 2024
Язык: Английский
Процитировано
11
Small, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 9, 2024
Bacterial infection and an excessive inflammatory response are two major factors that affect the healing of infected wounds. The zinc oxide/copper sulfide (ZnO-CuS) microspheres (MSs) developed in this work can kill bacteria resist inflammation. ZnO-CuS exhibits different enzyme-like activities depending on pH. In acidic environments, peroxidase-like (POD-like) activity convert hydrogen peroxide (H
Язык: Английский
Процитировано
9
Carbohydrate Polymers, Год журнала: 2024, Номер 342, С. 122403 - 122403
Опубликована: Июнь 19, 2024
Язык: Английский
Процитировано
4
Nano Letters, Год журнала: 2024, Номер 24(45), С. 14337 - 14345
Опубликована: Окт. 29, 2024
Nanomaterials with peroxidase-like activity and photothermal conversion efficiency have garnered significant attention for their ability to generate cytotoxic hydroxyl radicals provide synergistic therapeutic effects. Selecting nanozymes suitable properties carriers is crucial maximizing efficacy. While the mucin family known its mucoadhesive, glycosylated structures that enhance drug bioavailability targeting, potential in remains underexplored. Here, we utilize mucin-2 facilitate osmium nanoclusters (Os@Mucin), creating protein-corona-like nanozymes. This configuration bestows Os@Mucin excellent (769 U/mg) (22.83%, 808 nm). Mucin-2 promotes Os uptake by cells, allowing exhibit tumor environment-responsive activity, further enhanced under conditions targeted cytotoxicity
Язык: Английский
Процитировано
4
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159666 - 159666
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Biomaterials Science, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Wound healing is a complex and dynamic process often accompanied by bacterial infection, inflammation, excessive oxidative stress. Single-atom nanozymes with multi-enzymatic activities show significant potential for promoting the of infected wounds modulating their antibacterial anti-inflammatory properties in response to wound's physiological environment. In this study, we synthesized MN4 single-atom that intelligently respond pH value changes wound process. vitro experiments confirm effectiveness against Gram-negative bacteria, attributed elevated reactive oxygen species (ROS) accumulation within cells. Moreover, full-thickness skin wound-infected model demonstrates accelerate repair regeneration suppressing expression tumor necrosis factor-alpha (TNF-α), angiogenesis, enhancing collagen deposition. vivo biocompatibility further demonstrate favorable these nanozymes, highlighting clinical applications healing. These different microenvironments may be suitable addressing variable diseases.
Язык: Английский
Процитировано
0
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(31), С. 7519 - 7531
Опубликована: Янв. 1, 2024
A solvothermal method and the subsequent heat treatment process were developed to fabricate hollow ZnO particles with hierarchical pores on a large scale. The as-obtained hollow, porous microspheres tunable sizes, high specific surface areas, pH sensitivity, antibacterial properties, adsorption capacities showed significant advantages for drug delivery. Sprayable hydrogels containing curcumin nanoparticles (CNPs) prepared accelerate wound healing. water-dispersed CNPs promoted both migration of fibroblasts angiogenesis an aqueous solution Pluronic F127 (a temperature-sensitive phase-change hydrogel material) was shown be effective choice medical dressings. experimental data suggest that can loaded additional achieve continuous long-term therapeutic effects.
Язык: Английский
Процитировано
3
Microchimica Acta, Год журнала: 2024, Номер 191(8)
Опубликована: Июль 27, 2024
Язык: Английский
Процитировано
2