Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162536 - 162536
Опубликована: Апрель 1, 2025
Язык: Английский
Advanced Science, Год журнала: 2025, Номер unknown
Опубликована: Фев. 14, 2025
Abstract Severe bone and cartilage defects caused by trauma are challenging to treat, often resulting in poor outcomes. An endogenous electric field (EnEF) is crucial for regeneration, making electrical materials a promising therapy. This review provides comprehensive overview of the role bioelectric signals cells, alongside recent advancements biomaterials, with particular emphasis on nanogenerators, piezoelectric materials, triboelectric scaffolds, zwitterionic hydrogels. It further investigates impact these biomaterials as well applications both exogenous stimulation (ES) mechanisms underlying ES‐induced cellular molecular responses. Finally, underscores future directions ES systems tissue engineering, emphasizing critical importance integrating structural integrity, mechanical properties, signal delivery into intelligent implantable scaffolds.
Язык: Английский
Процитировано
4
Advanced Science, Год журнала: 2025, Номер unknown
Опубликована: Фев. 8, 2025
Sonodynamic therapy (SDT) represents a promising approach for cancer treatment. Compared to photodynamic therapy, SDT offers increased penetration depth and higher precision. However, the practical application of is constrained by low water solubility, poor tumor specificity, metabolic susceptibility most sonosensitizers. Recent research has explored use piezoelectric materials as sonosensitizers in treatment inhibition bacterial growth. Upon ultrasound excitation, separation electron-hole (e--h+) pairs occurs within material. By improving crystal structure material or incorporating other nanoparticles prevent rapid recombination e--h+ pairs, accumulates charges conduction band valence band, achieving redox potential O2/·O2 -. This enables serve sonosensitizer, leading concept termed Sono-Piezo Dynamic Therapy (SPDT). review aims define SPDT, provide systematic overview historical development SDT, elucidate mechanisms which act Importantly, various will be discussed terms their feasibility, advantages, disadvantages sonosensitizers, offering new perspectives identifying
Язык: Английский
Процитировано
3
Med-X, Год журнала: 2025, Номер 3(1)
Опубликована: Март 4, 2025
Язык: Английский
Процитировано
2
Advanced Functional Materials, Год журнала: 2025, Номер unknown
Опубликована: Янв. 28, 2025
Abstract Stringent environmental policies and sustainability targets are driving the adoption of lightweight materials in high‐performance transportation defense sectors. Inspired by nature's unparalleled engineering, this work introduces butterfly‐inspired hybrid composites that emulate multifunctional performance natural architectures. Specifically, these reinforced with hierarchical fibrous assemblies comprised nano‐sized graphene nanoplatelets covalently bonded onto micro‐sized glass fibers, emulating architecture butterfly legs. Additionally, sandwich‐structured designed to mimic alternating rigid porous layered scales wings, featuring a foamed composite core sandwiched between solid skins, leading superior mechanical thermal management performance. Compared current industrial substitute for metallic structural components, tailorable achieve improvements up 32%, 36%, 116% specific tensile strength, flexural impact respectively, as well 66% insulation 62% performance, 38% weight reduction. These advancements stem from detailed structure‐property designs, spanning across multiple length‐scales, formulating fundamental understanding how tune meet stringent requirements. Ultimately, cost‐effective, industry‐ready produce lightweight, components showcase potential biomimicry advancing sustainable engineering solutions.
Язык: Английский
Процитировано
1
MRS Bulletin, Год журнала: 2025, Номер unknown
Опубликована: Фев. 26, 2025
Язык: Английский
Процитировано
1
International Journal of Electrochemical Science, Год журнала: 2024, Номер 19(10), С. 100793 - 100793
Опубликована: Сен. 11, 2024
Язык: Английский
Процитировано
5
Nano Energy, Год журнала: 2024, Номер 131, С. 110346 - 110346
Опубликована: Окт. 10, 2024
Язык: Английский
Процитировано
5
ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(30), С. 38852 - 38879
Опубликована: Июль 23, 2024
Biophysical and clinical medical studies have confirmed that biological tissue lesions trauma are related to the damage of an intrinsic electret (i.e., endogenous electric field), such as wound healing, embryonic development, occurrence various diseases, immune regulation, regeneration, cancer metastasis. As exogenous electrical signals, conductivity, piezoelectricity, ferroelectricity, pyroelectricity, bioelectroactives can regulate field, thus controlling function cells promoting repair regeneration tissues. Materials, once polarized, harness their inherent polarized static fields generate field through direct stimulation or indirect interactions facilitated by physical friction, ultrasound, mechanical stimulation. The interaction with microenvironment allows for regulation compensation signals in damaged microenvironments, leading repair. technique shows great promise applications regeneration. In this paper, generation change electroactive substances expounded, latest research progress its effects include bone repair, nerve drug penetration promotion, etc. Finally, opportunities challenges materials were summarized. Exploring development new mechanism regulating changes may provide insights innovative methods disease treatment applications.
Язык: Английский
Процитировано
4
Nano Energy, Год журнала: 2024, Номер unknown, С. 110367 - 110367
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
4
Опубликована: Ноя. 21, 2024
Emerging piezoelectric metamaterials hold immense promise for biomedical applications by merging the intrinsic electrical properties of piezoelectricity with precise architecture metamaterials. This review provides a comprehensive overview various materials- such as molecular crystals, ceramics, and polymers-known their exceptional performance biocompatibility. We explore advanced engineering approaches, including design, supramolecular packing, 3D assembly, which enable customization targeted applications. Particular attention is given to pivotal role metamaterial structuring in development 0D spheres, 1D fibers tubes, 2D films, scaffolds. Key applications, tissue engineering, drug delivery, wound healing, biosensing, are discussed through illustrative examples. Finally, article addresses critical challenges future directions, aiming drive further innovations biomaterials next-generation healthcare technologies.
Язык: Английский
Процитировано
4